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Rifalazil(Kaneka corp).
Pregnolato M. Pregnolato M. IDrugs. 1998 Sep;1(5):599-604. IDrugs. 1998. PMID: 18465600
In preclinical in vitro studies, rifalazil was 30-fold more potent than rifampin against M tuberculosis and MAC, and has shown efficacy in animal models of tuberculosis and in disseminated MAC infections that have been predictive of clinical efficacy with other antibiotics [22416 …
In preclinical in vitro studies, rifalazil was 30-fold more potent than rifampin against M tuberculosis and MAC, and has shown efficacy in a …
High-performance liquid chromatographic determination of 3'-hydroxy-5'-(4-isobutyl-1-piperazinyl)benzoxazinorifamycin (KRM-1648) and its deacetyl metabolite in plasma, whole blood, urine and tissue samples in rats.
Hosoe K, Konishi E, Hidaka T, Yamane T, Yamashita K, Ohashi T. Hosoe K, et al. J Chromatogr B Biomed Appl. 1994 Mar 4;653(2):177-86. doi: 10.1016/0378-4347(93)e0431-o. J Chromatogr B Biomed Appl. 1994. PMID: 8205245
A reversed-phase high-performance liquid chromatographic method was developed for the determination of 3'-hydroxy-5'-(4-isobutyl-1-piperazinyl)benzoxazinorifamycin (KRM-1648, I), a new rifamycin derivative, and its 25-deacetyl metabolite (KRM-1671, II) in plasma, wh …
A reversed-phase high-performance liquid chromatographic method was developed for the determination of 3'-hydroxy-5'-(4-isobutyl-1-piperazin …