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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1992 3
1993 2
1994 4
1995 6
1996 5
1997 11
1998 9
1999 17
2000 26
2001 33
2002 37
2003 28
2004 42
2005 56
2006 62
2007 41
2008 83
2009 87
2010 99
2011 99
2012 105
2013 109
2014 102
2015 114
2016 85
2017 99
2018 89
2019 100
2020 94
2021 81
2022 52
2023 46
2024 9

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1,611 results

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Page 1
Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse.
Hingorani SR, Petricoin EF, Maitra A, Rajapakse V, King C, Jacobetz MA, Ross S, Conrads TP, Veenstra TD, Hitt BA, Kawaguchi Y, Johann D, Liotta LA, Crawford HC, Putt ME, Jacks T, Wright CV, Hruban RH, Lowy AM, Tuveson DA. Hingorani SR, et al. Cancer Cell. 2003 Dec;4(6):437-50. doi: 10.1016/s1535-6108(03)00309-x. Cancer Cell. 2003. PMID: 14706336 Free article.
Low HES-1 and positive DLL4 expression predicts poor prognosis of colorectal cancers.
Kim G, Jung J, Kim JW, Kim JY. Kim G, et al. Pathology. 2023 Feb;55(1):52-57. doi: 10.1016/j.pathol.2022.07.008. Epub 2022 Sep 8. Pathology. 2023. PMID: 36167746
Hairy and enhancer of split-1 (HES-1) is a downstream transcription factor and delta-like 4 (DLL4) is a ligand of the Notch signalling pathway. HES-1 and DLL4 expression are known to have an association with the progression and metastasis of cancers. . …
Hairy and enhancer of split-1 (HES-1) is a downstream transcription factor and delta-like 4 (DLL4) is a ligand of the Notch si …
Notch Signaling Pathway Expression in the Skin of Leprosy Patients: Association With Skin and Neural Damage.
Serrano-Coll H, Ospina JP, Salazar-Peláez L, Cardona-Castro N. Serrano-Coll H, et al. Front Immunol. 2020 Mar 19;11:368. doi: 10.3389/fimmu.2020.00368. eCollection 2020. Front Immunol. 2020. PMID: 32265900 Free PMC article.
In these samples, gene expressions of cellular components associated with the Notch signaling pathway, Hes-1, Hey-1, Runx-1 Jagged-1, Notch-1, and Numb, were evaluated using q-PCR, and protein expression was evaluated using immunohistochemistry of Runx-1 and …
In these samples, gene expressions of cellular components associated with the Notch signaling pathway, Hes-1, Hey-1, Runx-1 Ja …
Cigarette smoke upregulates Notch-1 signaling pathway and promotes lung adenocarcinoma progression.
Chiappara G, Di Vincenzo S, Sangiorgi C, Di Sano C, D'Anna C, Zito G, Cipollina C, Vitulo P, Bertani A, Pace E. Chiappara G, et al. Toxicol Lett. 2022 Feb 1;355:31-40. doi: 10.1016/j.toxlet.2021.11.002. Epub 2021 Nov 5. Toxicol Lett. 2022. PMID: 34748854
A549 were exposed to cigarette smoke extracts (2.5 % and 5 % CSE for 6, 24 and 48 h) and the expression of Notch-1, Jagged-1 and Hes-1 was evaluated by Real-Time PCR and Western Blot (nuclear fractions). ...Smokers lung parenchyma exhibited higher expression of Notc …
A549 were exposed to cigarette smoke extracts (2.5 % and 5 % CSE for 6, 24 and 48 h) and the expression of Notch-1, Jagged-1 and Hes- …
Sirt3 promotes the autophagy of HK-2 human proximal tubular epithelial cells via the inhibition of Notch-1/Hes-1 signaling.
Wang Y, Chang J, Wang ZQ, Li Y. Wang Y, et al. Mol Med Rep. 2021 Sep;24(3):634. doi: 10.3892/mmr.2021.12273. Epub 2021 Jul 19. Mol Med Rep. 2021. PMID: 34278469 Free PMC article.
Moreover, Sirt3 reversed the HG-induced inhibition of the Notch-1/Hes-1 signaling pathway. However, this autophagy-promoting effect of Sirt3 was counteracted by the Notch-1/Hes-1 pathway activator. On the whole, the present study demonstrated that Sirt …
Moreover, Sirt3 reversed the HG-induced inhibition of the Notch-1/Hes-1 signaling pathway. However, this autophagy-promoting e …
HES1 in immunity and cancer.
Rani A, Greenlaw R, Smith RA, Galustian C. Rani A, et al. Cytokine Growth Factor Rev. 2016 Aug;30:113-7. doi: 10.1016/j.cytogfr.2016.03.010. Epub 2016 Mar 19. Cytokine Growth Factor Rev. 2016. PMID: 27066918 Review.
Hairy and enhancer of split homolog-1 (HES1) is a part of an extensive family of basic helix-loop-helix (bHLH) proteins and plays a crucial role in the control and regulation of cell cycle, proliferation, cell differentiation, survival and apoptosis in neuronal, endocrine, …
Hairy and enhancer of split homolog-1 (HES1) is a part of an extensive family of basic helix-loop-helix (bHLH) proteins and plays a c …
Curcumin-mediated regulation of Notch1/hairy and enhancer of split-1/survivin: molecular targeting in cholangiocarcinoma.
Koprowski S, Sokolowski K, Kunnimalaiyaan S, Gamblin TC, Kunnimalaiyaan M. Koprowski S, et al. J Surg Res. 2015 Oct;198(2):434-40. doi: 10.1016/j.jss.2015.03.029. Epub 2015 Mar 19. J Surg Res. 2015. PMID: 25890434 Review.
Cell lysates were further analyzed via Western blotting for Notch1/HES-1/survivin pathway expression, cell cycle progression, and survival. ...To our knowledge, this is the first report showing reduction in HES-1 expression via protein analysis …
Cell lysates were further analyzed via Western blotting for Notch1/HES-1/survivin pathway expression, cell cycle progression, …
The Notch signaling cascade in neuroblastoma: role of the basic helix-loop-helix proteins HASH-1 and HES-1.
Axelson H. Axelson H. Cancer Lett. 2004 Feb 20;204(2):171-8. doi: 10.1016/S0304-3835(03)00453-1. Cancer Lett. 2004. PMID: 15013216 Review.
One important negative regulator of MASH-1 expression is the bHLH factor hairy and Enhancer of split homolog-1 (HES-1), which in turn is under positive control of the Notch signaling cascade. ...In this review, the role of the Notch-signaling cascade in neuroblastom …
One important negative regulator of MASH-1 expression is the bHLH factor hairy and Enhancer of split homolog-1 (HES-1), which …
1,611 results