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2002 1
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Page 1
Fiber-like Action of d-Fagomine on the Gut Microbiota and Body Weight of Healthy Rats.
Ramos-Romero S, Ponomarenko J, Amézqueta S, Hereu M, Miralles-Pérez B, Romeu M, Méndez L, Medina I, Torres JL. Ramos-Romero S, et al. Nutrients. 2022 Nov 3;14(21):4656. doi: 10.3390/nu14214656. Nutrients. 2022. PMID: 36364917 Free PMC article.
The goal of this work is to explore if the changes induced by d-fagomine in the gut microbiota are compatible with its effect on body weight and inflammation markers in rats. Methods: Sprague Dawley rats were fed a standard diet supplemented with d-fagomine (or not, …
The goal of this work is to explore if the changes induced by d-fagomine in the gut microbiota are compatible with its effect on body …
The Buckwheat Iminosugar d-Fagomine Attenuates Sucrose-Induced Steatosis and Hypertension in Rats.
Ramos-Romero S, Hereu M, Atienza L, Amézqueta S, Casas J, Muñoz S, Medina I, Miralles-Pérez B, Romeu M, Torres JL. Ramos-Romero S, et al. Mol Nutr Food Res. 2020 Jan;64(1):e1900564. doi: 10.1002/mnfr.201900564. Epub 2019 Nov 22. Mol Nutr Food Res. 2020. PMID: 31657510 Free article.
SCOPE: This study examines the long-term functional effects of d-fagomine on sucrose-induced factors of metabolic dysfunctions and explores possible molecular mechanisms behind its action. METHODS AND RESULTS: Wistar Kyoto rats are fed a 35% sucrose solution with d-fago
SCOPE: This study examines the long-term functional effects of d-fagomine on sucrose-induced factors of metabolic dysfunctions and ex …
Functional Effects of the Buckwheat Iminosugar d-Fagomine on Rats with Diet-Induced Prediabetes.
Ramos-Romero S, Hereu M, Atienza L, Casas J, Taltavull N, Romeu M, Amézqueta S, Dasilva G, Medina I, Torres JL. Ramos-Romero S, et al. Mol Nutr Food Res. 2018 Aug;62(16):e1800373. doi: 10.1002/mnfr.201800373. Epub 2018 Aug 1. Mol Nutr Food Res. 2018. PMID: 29979820 Free article.
CONCLUSION: d-Fagomine delays the development of a fat-induced prediabetic state in rats by reducing low-grade inflammation. We suggest that the anti-inflammatory effect of d-fagomine may be linked to a reduction in fat-induced overpopulation of minor gut bacteria.. …
CONCLUSION: d-Fagomine delays the development of a fat-induced prediabetic state in rats by reducing low-grade inflammation. We sugge …
Effect of (D)-fagomine on excreted Enterobacteria and weight gain in rats fed a high-fat high-sucrose diet.
Ramos-Romero S, Molinar-Toribio E, Gómez L, Pérez-Jiménez J, Casado M, Clapés P, Piña B, Torres JL. Ramos-Romero S, et al. Obesity (Silver Spring). 2014 Apr;22(4):976-9. doi: 10.1002/oby.20640. Epub 2013 Dec 4. Obesity (Silver Spring). 2014. PMID: 24124117 Free article.
The levels of Enterobacteriales and E. coli of the rats given HFHS with d-fagomine were similar to those of the rats fed a standard diet. Compared to the standard group, rats fed HFHS with d-fagomine gained significantly less weight (15.3%) than those fed HFHS (20.9 …
The levels of Enterobacteriales and E. coli of the rats given HFHS with d-fagomine were similar to those of the rats fed a standard d …
Fate of d-Fagomine after Oral Administration to Rats.
Amézqueta S, Ramos-Romero S, Martínez-Guimet C, Moreno A, Hereu M, Torres JL. Amézqueta S, et al. J Agric Food Chem. 2017 Jun 7;65(22):4414-4420. doi: 10.1021/acs.jafc.7b01026. Epub 2017 May 22. J Agric Food Chem. 2017. PMID: 28489364
This paper evaluates the excretion and metabolism of orally administered d-fagomine in rats and compares outcomes with the fate of 1-deoxynojirimycin. d-Fagomine and 1-deoxynojirimycin show similar absorption and excretion kinetics. d-Fagomine is partly absor …
This paper evaluates the excretion and metabolism of orally administered d-fagomine in rats and compares outcomes with the fate of 1- …
The presence of D-fagomine in the human diet from buckwheat-based foodstuffs.
Amézqueta S, Galán E, Vila-Fernández I, Pumarola S, Carrascal M, Abian J, Ribas-Barba L, Serra-Majem L, Torres JL. Amézqueta S, et al. Food Chem. 2013 Feb 15;136(3-4):1316-21. doi: 10.1016/j.foodchem.2012.09.038. Epub 2012 Sep 18. Food Chem. 2013. PMID: 23194529
Buckwheat (Fagopyrum esculentum Moench) groats contain the iminosugar D-fagomine as a minor component that might contribute to the alleged health benefits of this pseudo-cereal. ...The estimated total intake of D-fagomine resulting from a diet that includes such foo …
Buckwheat (Fagopyrum esculentum Moench) groats contain the iminosugar D-fagomine as a minor component that might contribute to the al …
D-Fagomine lowers postprandial blood glucose and modulates bacterial adhesion.
Gómez L, Molinar-Toribio E, Calvo-Torras MÁ, Adelantado C, Juan ME, Planas JM, Cañas X, Lozano C, Pumarola S, Clapés P, Torres JL. Gómez L, et al. Br J Nutr. 2012 Jun;107(12):1739-46. doi: 10.1017/S0007114511005009. Epub 2011 Oct 3. Br J Nutr. 2012. PMID: 22017795
D-Fagomine is an iminosugar originally isolated from seeds of buckwheat (Fagopyrum sculentum Moench), present in the human diet and now available as a pure crystalline product. ...D-Fagomine did not show any effect on bacterial cell viability. Based on all this evid …
D-Fagomine is an iminosugar originally isolated from seeds of buckwheat (Fagopyrum sculentum Moench), present in the human diet and n …
D-Fagomine attenuates metabolic alterations induced by a high-energy-dense diet in rats.
Molinar-Toribio E, Pérez-Jiménez J, Ramos-Romero S, Gómez L, Taltavull N, Nogués MR, Adeva A, Jáuregui O, Joglar J, Clapés P, Torres JL. Molinar-Toribio E, et al. Food Funct. 2015 Aug;6(8):2614-9. doi: 10.1039/c5fo00591d. Epub 2015 Jul 1. Food Funct. 2015. PMID: 26130374
This suggests that supplementation with d-fagomine for longer periods may delay the onset of other factors related to metabolic syndrome. Here we evaluate the effects of d-fagomine dietary supplementation on relevant metabolic hormones and lipid peroxidation. ...
This suggests that supplementation with d-fagomine for longer periods may delay the onset of other factors related to metabolic syndr …
Metabolism, transformation and dynamic changes of alkaloids in silkworm during feeding mulberry leaves.
Zhang L, Bai Y, Su S, Ouyang Z, Liu L, Pan G, Qian D, Duan J. Zhang L, et al. Nat Prod Res. 2019 Apr;33(8):1182-1190. doi: 10.1080/14786419.2018.1465422. Epub 2018 Jun 4. Nat Prod Res. 2019. PMID: 29862842
Metabolism, transformation and dynamic changes of DNJ, 2-O-alpha-D-Gal-DNJ, fagomine, isofagomine and 4-O-beta-d-Glc-fagomine from mulberry leaves in silkworms at different instars were observed. ...The experimental results indicated that DNJ and its derivatives tur …
Metabolism, transformation and dynamic changes of DNJ, 2-O-alpha-D-Gal-DNJ, fagomine, isofagomine and 4-O-beta-d-Glc-fagomine
d-Fagomine Attenuates High Glucose-Induced Endothelial Cell Oxidative Damage by Upregulating the Expression of PGC-1alpha.
Chun-Fang, Zhang BB, Lin-Han, Gao CF, Min-Wang. Chun-Fang, et al. J Agric Food Chem. 2018 Mar 21;66(11):2758-2764. doi: 10.1021/acs.jafc.7b05942. Epub 2018 Feb 28. J Agric Food Chem. 2018. PMID: 29489344
d-Fagomine, an analogue of 1-deoxynojirimycin (DNJ), has been shown to have hypoglycemic activity. ...Our results showed that d-fagomine reduced intracellular reactive oxygen species (ROS) production and malondialdehyde (MDA) levels. ...
d-Fagomine, an analogue of 1-deoxynojirimycin (DNJ), has been shown to have hypoglycemic activity. ...Our results showed that d-fa
80 results