Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2007 1
2010 1
2012 1
2013 1
2024 0

Text availability

Article attribute

Article type

Publication date

Search Results

3 results

Results by year

Filters applied: . Clear all
Page 1
In vitro metabolism of the 5-hydroxytryptamine1B receptor antagonist elzasonan.
Kamel A, Colizza K, Obach RS. Kamel A, et al. Xenobiotica. 2013 Apr;43(4):368-78. doi: 10.3109/00498254.2012.723150. Epub 2012 Oct 3. Xenobiotica. 2013. PMID: 23030680
The metabolism of elzasonan has been examined in vitro using hepatic microsomes from human and recombinant heterologously expressed P450 enzymes (rCYP). Metabolism occurs primarily via oxidative N-demethylation to form M4 and oxidation reactions to form elzasonan N- …
The metabolism of elzasonan has been examined in vitro using hepatic microsomes from human and recombinant heterologously expressed P …
Metabolism, pharmacokinetics, and excretion of the 5-hydroxytryptamine1b receptor antagonist elzasonan in humans.
Kamel A, Obach RS, Colizza K, Wang W, O'Connell TN, Coelho RV Jr, Kelley RM, Schildknegt K. Kamel A, et al. Drug Metab Dispos. 2010 Nov;38(11):1984-99. doi: 10.1124/dmd.110.034595. Epub 2010 Jul 28. Drug Metab Dispos. 2010. PMID: 20668248
The metabolism, pharmacokinetics, and excretion of a potent and selective 5-hydroxytryptamine(1B) receptor antagonist elzasonan have been studied in six healthy male human subjects after oral administration of a single 10-mg dose of [(14)C]elzasonan. Total recovery …
The metabolism, pharmacokinetics, and excretion of a potent and selective 5-hydroxytryptamine(1B) receptor antagonist elzasonan have …
Assessing the onset of antidepressant-induced sexual dysfunction using interactive voice response technology.
Dunn JA, Arakawa R, Greist JH, Clayton AH. Dunn JA, et al. J Clin Psychiatry. 2007 Apr;68(4):525-32. doi: 10.4088/jcp.v68n0406. J Clin Psychiatry. 2007. PMID: 17474807 Clinical Trial.
METHOD: Sexually active, healthy male volunteers (N = 99; mean age of 31 years) were randomly assigned to 3 weeks of double-blind, parallel-group treatment with paroxetine (20 mg/day); CP-448,187 (3 mg/day); or placebo. Patients completed both paper-and-penci …
METHOD: Sexually active, healthy male volunteers (N = 99; mean age of 31 years) were randomly assigned to 3 weeks of double-blind, parallel- …