Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1986 1
1988 1
1990 3
1991 3
1992 3
1993 1
1994 3
1995 1
2001 2
2002 2
2004 1
2005 1
2006 3
2009 1
2013 1
2014 1
2024 0

Text availability

Article attribute

Article type

Publication date

Search Results

28 results

Results by year

Filters applied: . Clear all
Page 1
Cold instability of aponeocarzinostatin and its stabilization by labile chromophore.
Jayachithra K, Kumar TK, Lu TJ, Yu C, Chin DH. Jayachithra K, et al. Biophys J. 2005 Jun;88(6):4252-61. doi: 10.1529/biophysj.104.051722. Epub 2005 Apr 8. Biophys J. 2005. PMID: 15821162 Free PMC article.
The conformational stability of aponeocarzinostatin, an all-beta-sheet protein with 113 amino-acid residues, is investigated by thermal-induced equilibrium unfolding between pH 2.0 and 10.0 with and without urea. At room temperature, the protein is stable in a pH range of …
The conformational stability of aponeocarzinostatin, an all-beta-sheet protein with 113 amino-acid residues, is investigated by therm …
A superior drug carrier--aponeocarzinostatin in partially unfolded state fully protects the labile antitumor enediyne.
Shanmuganathan A, Kumar TK, Huang CM, Yu C, Chin DH. Shanmuganathan A, et al. J Biomed Sci. 2009 May 23;16(1):48. doi: 10.1186/1423-0127-16-48. J Biomed Sci. 2009. PMID: 19463188 Free PMC article.
METHODS: We characterized an intermediate in the equilibrium unfolding pathway of aponeocarzinostatin, using a variety of biophysical techniques including 1-anilino-8-napthalene sulfonate binding studies, size-exclusion fast protein liquid chromatography, intrinsic tryptop …
METHODS: We characterized an intermediate in the equilibrium unfolding pathway of aponeocarzinostatin, using a variety of biophysical …
Sequential 1H NMR assignment of the complex of aponeocarzinostatin with ethidium bromide and investigation of protein-drug interactions in the chromophore binding site.
Mohanty S, Sieker LC, Drobny GP. Mohanty S, et al. Biochemistry. 1994 Sep 6;33(35):10579-90. doi: 10.1021/bi00201a003. Biochemistry. 1994. PMID: 8075058
Two-dimensional 1H NMR spectroscopy has been used to investigate the binding site, binding interactions, and the conformation of a 1:1 complex of aponeocarzinostatin (apo-NCS) with ethidium bromide in solution. The protein component in the complex has been sequence-specifi …
Two-dimensional 1H NMR spectroscopy has been used to investigate the binding site, binding interactions, and the conformation of a 1:1 compl …
CO2.- radical induced cleavage of disulfide bonds in proteins. A gamma-ray and pulse radiolysis mechanistic investigation.
Favaudon V, Tourbez H, Houée-Levin C, Lhoste JM. Favaudon V, et al. Biochemistry. 1990 Dec 11;29(49):10978-89. doi: 10.1021/bi00501a016. Biochemistry. 1990. PMID: 2125498
Disulfide bond reduction by the CO2.- radical was investigated in aponeocarzinostatin, aporiboflavin-binding protein, and bovine immunoglobulin. ...
Disulfide bond reduction by the CO2.- radical was investigated in aponeocarzinostatin, aporiboflavin-binding protein, and bovine immu …
A new model for ligand release. Role of side chain in gating the enediyne antibiotic.
Hariharan P, Liang W, Chou SH, Chin DH. Hariharan P, et al. J Biol Chem. 2006 Jun 9;281(23):16025-33. doi: 10.1074/jbc.M600841200. Epub 2006 Mar 27. J Biol Chem. 2006. PMID: 16567802 Free article.
We report, herein, that subtle changes in the side chains of specific amino acid residues are adequate to gate the release of chromophore. A recombinant wild type aponeocarzinostatin and its variants mutated around the opening of the chromophore binding cleft are employed …
We report, herein, that subtle changes in the side chains of specific amino acid residues are adequate to gate the release of chromophore. A …
Aponeocarzinostatin--a superior drug carrier exhibiting unusually high endurance against denaturants.
Sudhahar CG, Chin DH. Sudhahar CG, et al. Bioorg Med Chem. 2006 May 15;14(10):3543-52. doi: 10.1016/j.bmc.2006.01.012. Epub 2006 Feb 3. Bioorg Med Chem. 2006. PMID: 16458518
To simulate conceivably offensive environment in biological contexts, such as cell membrane, we studied structural endurance of aponeocarzinostatin against several denaturants by circular dichroism and nuclear magnetic resonance spectroscopy. For comparison, we also examin …
To simulate conceivably offensive environment in biological contexts, such as cell membrane, we studied structural endurance of aponeocar …
Synthetic ligands for apo-neocarzinostatin.
Caddick S, Muskett FW, Stoneman RG, Woolfson DN. Caddick S, et al. J Am Chem Soc. 2006 Apr 5;128(13):4204-5. doi: 10.1021/ja058419i. J Am Chem Soc. 2006. PMID: 16568976
28 results