Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1991 1
1995 2
2024 0

Text availability

Article attribute

Article type

Publication date

Search Results

3 results

Results by year

Filters applied: . Clear all
Page 1
Minimal cardiac electrophysiological activity of alprenoxime, a site-activated ocular beta-blocker, in dogs.
Polgar P, Bodor N. Polgar P, et al. Life Sci. 1995;56(14):1207-13. doi: 10.1016/0024-3205(95)00060-j. Life Sci. 1995. PMID: 7475898
No changes greater than 6% from baseline were detected with alprenoxime infusion. Similarly, no beta-antagonist cardiac activity could be detected in isoproterenol stimulated dogs after alprenoxime. The results demonstrate that alprenoxime has no significant …
No changes greater than 6% from baseline were detected with alprenoxime infusion. Similarly, no beta-antagonist cardiac activity coul …
Improved delivery through biological membranes. LVI. Pharmacological evaluation of alprenoxime--a new potential antiglaucoma agent.
Bodor N, Elkoussi A. Bodor N, et al. Pharm Res. 1991 Nov;8(11):1389-95. doi: 10.1023/a:1015849123020. Pharm Res. 1991. PMID: 1798675
A new site-specific chemical delivery system (CDS) for alprenolol was designed and investigated as a potential novel antiglaucoma agent. The effect of this compound, alprenoxime (AO), on the intraocular pressure (IOP) of rabbits was evaluated after its uni- and bilateral a …
A new site-specific chemical delivery system (CDS) for alprenolol was designed and investigated as a potential novel antiglaucoma agent. The …
Sequential bioactivation of methoxime analogs of beta-adrenergic antagonists in the eye.
Bodor N, Prokai L, Wu WM, Somogyi G, Farag H. Bodor N, et al. J Ocul Pharmacol Ther. 1995 Fall;11(3):305-18. doi: 10.1089/jop.1995.11.305. J Ocul Pharmacol Ther. 1995. PMID: 8590263
The corresponding ketoxime analogs of the various beta-blockers were successfully applied and one of them, Alprenoxime, was tested in humans. The main problem with these compounds, however, is formulation stability: Alprenoxime has a t90 of only 2-3 months. ...
The corresponding ketoxime analogs of the various beta-blockers were successfully applied and one of them, Alprenoxime, was tested in …