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1963 1
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Page 1
TLC determination of griseofulvin in plasma and 6-demethylgriseofulvin in urine.
Garceau Y, Brisson J, Davis I, DeAngelis RL, Hasegawa J. Garceau Y, et al. J Pharm Sci. 1980 May;69(5):561-3. doi: 10.1002/jps.2600690523. J Pharm Sci. 1980. PMID: 7381744
For griseofulvin, the quantitation limit is 20 ng/ml of plasma and the recovery is 100%; for 6-demethylgriseofulvin, the limit is 1 microgram/ml of urine and the recovery is 90%. The methods were used to determine the plasma levels of griseofulvin and the amount of …
For griseofulvin, the quantitation limit is 20 ng/ml of plasma and the recovery is 100%; for 6-demethylgriseofulvin, the limit …
Human plasma and skin blister fluid levels of griseofulvin after its repeated administration.
Schäfer-Korting M, Korting HC, Mutschler E. Schäfer-Korting M, et al. Eur J Clin Pharmacol. 1985;29(3):351-4. doi: 10.1007/BF00544093. Eur J Clin Pharmacol. 1985. PMID: 4076331
The drug was determined in plasma, suction blister fluid (SBF) and cantharides blister fluid (CBF) following the last dose. Urinary excretion of the main metabolites 6-demethylgriseofulvin (6-DMG) and its glucuronic acid conjugate was also measured. ...
The drug was determined in plasma, suction blister fluid (SBF) and cantharides blister fluid (CBF) following the last dose. Urinary excretio …
Human plasma and skin blister fluid levels of griseofulvin following a single oral dose.
Schäfer-Korting M, Korting HC, Mutschler E. Schäfer-Korting M, et al. Eur J Clin Pharmacol. 1985;29(1):109-13. doi: 10.1007/BF00547378. Eur J Clin Pharmacol. 1985. PMID: 4054199
Griseofulvin and 6-demethylgriseofulvin (6-DMG) in plasma, suction blister fluid (SBF) and cantharides blister fluid (CBF) and urinary excretion of 6-DMG, were evaluated following administration of single oral doses of an ultramicrosize and a microsize formulation o …
Griseofulvin and 6-demethylgriseofulvin (6-DMG) in plasma, suction blister fluid (SBF) and cantharides blister fluid (CBF) and …
Metabolite profiling using liquid chromatography/quadrupole time-of-flight mass spectrometry for the identification of a suitable marker and target matrix of griseofulvin use in bovines.
Tarbin JA, Fussell RJ. Tarbin JA, et al. Rapid Commun Mass Spectrom. 2013 Jun 30;27(12):1287-93. doi: 10.1002/rcm.6574. Rapid Commun Mass Spectrom. 2013. PMID: 23681805
Data from fragmentation experiments enabled a tentative assignment of the structures of the two compounds as 4-demethylgriseofulvin and 6-demethylgriseofulvin. These assignments were confirmed by matching the product ion spectra of incurred residues to those of cust …
Data from fragmentation experiments enabled a tentative assignment of the structures of the two compounds as 4-demethylgriseofulvin and 6
Determination of 6-demethylgriseofulvin in urine.
Rowland M, Riegelman S. Rowland M, et al. J Pharm Sci. 1973 Dec;62(12):2030-2. doi: 10.1002/jps.2600621230. J Pharm Sci. 1973. PMID: 4762179 No abstract available.
High-pressure liquid chromatographic assay for griseofulvin in plasma.
Meyer MC, Raghow G. Meyer MC, et al. J Pharm Sci. 1979 Sep;68(9):1127-30. doi: 10.1002/jps.2600680918. J Pharm Sci. 1979. PMID: 501535
The method was compared to two fluorometric assay methods and was more specific for griseofulvin. Assay of 6-demethylgriseofulvin isolated from human urine demonstrated that this material was not responsible for the interferences apparent in the fluorometric procedu …
The method was compared to two fluorometric assay methods and was more specific for griseofulvin. Assay of 6-demethylgriseofulvin
The in vitro liberation and the bioavailability of different brands of griseofulvin in plasma and urine in man.
Terhaag B, Le Petit G, Pachaly C, Feller K. Terhaag B, et al. Int J Clin Pharmacol Ther Toxicol. 1985 Sep;23(9):475-9. Int J Clin Pharmacol Ther Toxicol. 1985. PMID: 4055158
Contradictory results of the bioavailability are found by determining the amount of 6-Demethylgriseofulvin eliminated in urine. The elimination of this main metabolite after dosing with L is lower (0.18 +/- 0.02 mmol) than those of the other two brands, which do not …
Contradictory results of the bioavailability are found by determining the amount of 6-Demethylgriseofulvin eliminated in urine …
Liquid-solid chromatographic determination of 6-demethylgriseofulvin in urine.
Papp E, Magyar K, Schwarz HJ. Papp E, et al. J Pharm Sci. 1976 Mar;65(3):441-3. doi: 10.1002/jps.2600650335. J Pharm Sci. 1976. PMID: 4603
A specific and quantitative liquid-solid chromatographic method for the determination of 6-demethylgriseofulvin in human urine is reported. The method consists of extraction into an organic solvent, addition of internal standard, and analysis by liquid-solid chromat …
A specific and quantitative liquid-solid chromatographic method for the determination of 6-demethylgriseofulvin in human urine …
Chromatographic analysis of griseofulvin and metabolites in biological fluids.
Zia H, Proveaux WJ, O'Donnell JP, Ma JK. Zia H, et al. J Chromatogr. 1980 Jan 11;181(1):77-84. doi: 10.1016/s0378-4347(00)81271-2. J Chromatogr. 1980. PMID: 7364918
The described method allows one to quantitatively determine griseofulvin, 6-demethylgriseofulvin, and griseofulvic acid, a newly identified metabolite in man, in urine and plasma samples. ...
The described method allows one to quantitatively determine griseofulvin, 6-demethylgriseofulvin, and griseofulvic acid, a new …
15 results