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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1949 1
1950 1
1951 1
1953 2
1954 1
1957 1
1958 1
1962 6
1963 1
1965 2
1966 3
1968 5
1969 2
1970 3
1971 2
1972 6
1973 11
1974 11
1975 24
1976 21
1977 17
1978 20
1979 21
1980 38
1981 40
1982 45
1983 51
1984 57
1985 38
1986 40
1987 56
1988 53
1989 57
1990 44
1991 33
1992 33
1993 61
1994 47
1995 54
1996 52
1997 63
1998 52
1999 43
2000 64
2001 40
2002 57
2003 45
2004 44
2005 51
2006 61
2007 51
2008 62
2009 71
2010 82
2011 176
2012 185
2013 269
2014 306
2015 310
2016 364
2017 334
2018 301
2019 349
2020 318
2021 379
2022 359
2023 305
2024 82

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5,330 results

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Page 1
Bisulfite-free direct detection of 5-methylcytosine and 5-hydroxymethylcytosine at base resolution.
Liu Y, Siejka-Zielińska P, Velikova G, Bi Y, Yuan F, Tomkova M, Bai C, Chen L, Schuster-Böckler B, Song CX. Liu Y, et al. Nat Biotechnol. 2019 Apr;37(4):424-429. doi: 10.1038/s41587-019-0041-2. Epub 2019 Feb 25. Nat Biotechnol. 2019. PMID: 30804537
Bisulfite sequencing has been the gold standard for mapping DNA modifications including 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC) for decades(1-4). ...
Bisulfite sequencing has been the gold standard for mapping DNA modifications including 5-methylcytosine (5mC) and 5-hydroxyme …
The role of RNA m5C modification in cancer metastasis.
Zhang Q, Liu F, Chen W, Miao H, Liang H, Liao Z, Zhang Z, Zhang B. Zhang Q, et al. Int J Biol Sci. 2021 Aug 2;17(13):3369-3380. doi: 10.7150/ijbs.61439. eCollection 2021. Int J Biol Sci. 2021. PMID: 34512153 Free PMC article. Review.
As an inevitable component of the epigenetic regulatory network, 5-methylcytosine is associated with multifarious cellular processes and systemic diseases, including cell migration and cancer metastasis. ...
As an inevitable component of the epigenetic regulatory network, 5-methylcytosine is associated with multifarious cellular pro …
The DNA methylation landscape in cancer.
Skvortsova K, Stirzaker C, Taberlay P. Skvortsova K, et al. Essays Biochem. 2019 Dec 20;63(6):797-811. doi: 10.1042/EBC20190037. Essays Biochem. 2019. PMID: 31845735 Free PMC article. Review.
TET enzymes, TDG and the dynamics of DNA demethylation.
Kohli RM, Zhang Y. Kohli RM, et al. Nature. 2013 Oct 24;502(7472):472-9. doi: 10.1038/nature12750. Nature. 2013. PMID: 24153300 Free PMC article. Review.
The transformative discovery that ten-eleven translocation (TET) family enzymes can oxidize 5-methylcytosine has greatly advanced our understanding of DNA demethylation. 5-Hydroxymethylcytosine is a key nexus in demethylation that can either be passively depleted th …
The transformative discovery that ten-eleven translocation (TET) family enzymes can oxidize 5-methylcytosine has greatly advan …
Translating the epitranscriptome.
Hoernes TP, Erlacher MD. Hoernes TP, et al. Wiley Interdiscip Rev RNA. 2017 Jan;8(1):e1375. doi: 10.1002/wrna.1375. Epub 2016 Jun 27. Wiley Interdiscip Rev RNA. 2017. PMID: 27345446 Free PMC article. Review.
Thus far, N(6) -methyladenosine (m(6) A), pseudouridine (psi), 5-methylcytosine (m(5) C) and N(1) -methyladenosine (m(1) A) were identified in eukaryal, and to some extent in prokaryal mRNAs. ...
Thus far, N(6) -methyladenosine (m(6) A), pseudouridine (psi), 5-methylcytosine (m(5) C) and N(1) -methyladenosine (m(1) A) we …
The role of 5-hydroxymethylcytosine in melanoma.
Li FJ, Li LM, Zhang RH, Xu C, Zhou P, Long J, Hu G, Jiang MJ. Li FJ, et al. Melanoma Res. 2017 Jun;27(3):175-179. doi: 10.1097/CMR.0000000000000349. Melanoma Res. 2017. PMID: 28225433 Review.
The epigenetic mark 5-hydroxymethylcytosine (5-hmC) has attracted interest since 2009, when it was shown that ten-eleven translocation proteins can enzymatically convert 5-methylcytosine into 5-hmC, a key intermediate of DNA demethylation. ...
The epigenetic mark 5-hydroxymethylcytosine (5-hmC) has attracted interest since 2009, when it was shown that ten-eleven translocation prote …
5-methylcytosine and its derivatives.
Yuan BF. Yuan BF. Adv Clin Chem. 2014;67:151-87. doi: 10.1016/bs.acc.2014.09.003. Epub 2014 Nov 4. Adv Clin Chem. 2014. PMID: 25735861 Review.
DNA methylation, consisting of the addition of a methyl group at the fifth position of cytosine (5-methylcytosine, 5-mC) in a CpG dinucleotide, is a well-recognized epigenetic mark with important functions in cellular development and pathogenesis. ...
DNA methylation, consisting of the addition of a methyl group at the fifth position of cytosine (5-methylcytosine, 5-mC) in a …
The metabolism of 5-methylcytosine residues in DNA.
Murín R, Abdalla M, Murínová N, Hatok J, Dobrota D. Murín R, et al. Physiol Res. 2018 Jul 17;67(3):383-389. doi: 10.33549/physiolres.933550. Epub 2018 Mar 12. Physiol Res. 2018. PMID: 29527909 Free article. Review.
The fundamental biochemical processes of 5-methylcytosine (5-mC) synthesis, maintenance, conversion and removal determine the time and spatial pattern of DNA methylation. ...
The fundamental biochemical processes of 5-methylcytosine (5-mC) synthesis, maintenance, conversion and removal determine the …
Purification of TET Proteins.
Huang Z, Yu J, Johnson J, Jin SG, Pfeifer GP. Huang Z, et al. Methods Mol Biol. 2021;2272:225-237. doi: 10.1007/978-1-0716-1294-1_13. Methods Mol Biol. 2021. PMID: 34009617
The 5-methylcytosine (5mC) oxidation pathway mediated by TET proteins involves step-wise oxidation of 5mC to 5-hydroxymethylcytosine (5hmC), 5-formylcytosine (5fC), and 5-carboxylcytosine (5caC). 5fC and 5caC can be removed from DNA by base excision repair and the c …
The 5-methylcytosine (5mC) oxidation pathway mediated by TET proteins involves step-wise oxidation of 5mC to 5-hydroxymethylcy …
5,330 results