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1971 1
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759 results

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Page 1
The effect of 5,8,11,14-eicosatetraynoic acid on lipid metabolism.
Tobias LD, Hamilton JG. Tobias LD, et al. Lipids. 1979 Feb;14(2):181-93. doi: 10.1007/BF02533870. Lipids. 1979. PMID: 106197 Review.
The purpose of this presentation is to review the current state of knowledge regarding 5,8,11,14-eicosatetraynoic acid (ETYA, Ro 3-1428) and its effects on lipid metabolism. ...
The purpose of this presentation is to review the current state of knowledge regarding 5,8,11,14-eicosatetray …
Evidence for inhibition of leukotriene A4 synthesis by 5,8,11,14-eicosatetraynoic acid in guinea pig polymorphonuclear leukocytes.
Bokoch GM, Reed PW. Bokoch GM, et al. J Biol Chem. 1981 May 10;256(9):4156-9. J Biol Chem. 1981. PMID: 6260789 Free article.
The sensitivity of the 5-lipoxygenase to inhibition by 5,8,11,14-eicosatetraynoic acid (ETYA) is species- and/or tissue-dependent. Guinea pig peritoneal polymorphonuclear leukocytes prelabeled with [3H]arachidonic acid and stimulat …
The sensitivity of the 5-lipoxygenase to inhibition by 5,8,11,14-eicosatetraynoic acid (ETYA) is s …
Inhibition of U937 eicosanoid and DNA synthesis by 5,8,11,14-eicosatetraynoic acid, an inhibitor of arachidonic acid metabolism and its partial reversal by leukotriene C4.
Ondrey F, Harris JE, Anderson KM. Ondrey F, et al. Cancer Res. 1989 Mar 1;49(5):1138-42. Cancer Res. 1989. PMID: 2492901
When replicating U937 cells were incubated with up to 80 microM concentrations of the in vitro inhibitor of eicosanoid biosynthesis, 5,8,11,14-eicosatetraynoic acid (ETYA), DNA synthesis measured by labeling with [3H]thymidine was inhibit …
When replicating U937 cells were incubated with up to 80 microM concentrations of the in vitro inhibitor of eicosanoid biosynthesis, 5 …
Spontaneous chemiluminescence of ETYA (5,8,11,14-eicosatetraynoic acid) is inhibited by catalase or peroxidase.
Anderson KM, Petrik D, Mullane K, Harris JE. Anderson KM, et al. Prostaglandins Leukot Essent Fatty Acids. 1994 Oct;51(4):271-5. doi: 10.1016/0952-3278(94)90191-0. Prostaglandins Leukot Essent Fatty Acids. 1994. PMID: 7846095
5,8,11,14-eicosatetraynoic acid (ETYA), an isomorphic competitive analogue of arachidonic acid, spontaneously generates a chemiluminescence signal detected with a liquid scintillation spectrometer operated at ambient temperature in …
5,8,11,14-eicosatetraynoic acid (ETYA), an isomorphic competitive analogue of arachidonic acid …
5, 8, 11, 14-eicosatetraynoic acid suppresses CCL2/MCP-1 expression in IFN-gamma-stimulated astrocytes by increasing MAPK phosphatase-1 mRNA stability.
Lee JH, Kim H, Woo JH, Joe EH, Jou I. Lee JH, et al. J Neuroinflammation. 2012 Feb 18;9:34. doi: 10.1186/1742-2094-9-34. J Neuroinflammation. 2012. PMID: 22339770 Free PMC article.
BACKGROUND: The peroxisome proliferator-activated receptor (PPAR)-alpha activator, 5,8,11,14-eicosatetraynoic acid (ETYA), is an arachidonic acid analog. ...
BACKGROUND: The peroxisome proliferator-activated receptor (PPAR)-alpha activator, 5,8,11,14-eicosatetraynoic …
Inhibition of 12-O-tetradecanoylphorbol-13-acetate-accelerated phospholipid metabolism by 5,8,11,14-eicosatetraynoic acid.
Wertz PW, Mueller GC. Wertz PW, et al. Cancer Res. 1980 Mar;40(3):776-81. Cancer Res. 1980. PMID: 7008936
This action is prevented by high concentrations of the cyclooxygenase inhibitor, indomethacin (1 to 3 mM), suggesting a possible involvement of lipid oxidation in the response. The acetylenic analog of arachidonic acid, 5,8,11,14-eicosatetray …
This action is prevented by high concentrations of the cyclooxygenase inhibitor, indomethacin (1 to 3 mM), suggesting a possible involvement …
Inhibition of neutrophil phospholipase A2 by p-bromophenylacyl bromide, nordihydroguaiaretic acid, 5,8,11,14-eicosatetraynoic acid and quercetin.
Lanni C, Becker EL. Lanni C, et al. Int Arch Allergy Appl Immunol. 1985;76(3):214-7. doi: 10.1159/000233694. Int Arch Allergy Appl Immunol. 1985. PMID: 3972457
The lipoxygenase and/or cyclooxygenase inhibitors nordihydroguaiaretic acid (NDGA), 4,8,11,14-eicosatetraynoic acid (ETYA) and the bioflavonoid, quercetin, also inhibit phospholipase A2 (phosphatidase 2-acyl hydrolase; EC 3.1.1.4) activity of neutrophil ac …
The lipoxygenase and/or cyclooxygenase inhibitors nordihydroguaiaretic acid (NDGA), 4,8,11,14-eicosatetraynoic acid (ET …
Arachidonic acid metabolism and modulation of in vitro anaphylaxis by 5,8,11,14-eicosatetraynoic acid and 9a,12a-octadecadiynoic acid.
Hitchcock M, Kokolis NA. Hitchcock M, et al. Br J Pharmacol. 1981 Apr;72(4):689-95. doi: 10.1111/j.1476-5381.1981.tb09150.x. Br J Pharmacol. 1981. PMID: 6793116 Free PMC article.
1. 5,8,11,14-Eicosatetraynoic acid (ETYA) inhibited the antigen-induced contractions of tracheal spirals obtained from actively sensitized guinea-pigs. ...Under these conditions there may be redirection of the metabolism of arachidonic …
1. 5,8,11,14-Eicosatetraynoic acid (ETYA) inhibited the antigen-induced contractions of tracheal s …
5,8,11,14-eicosatetraynoic acid inhibits PC3 DNA synthesis and cellular proliferation, in part due to its 5'-lipoxygenase activity.
Anderson KM, Harris JE. Anderson KM, et al. Clin Physiol Biochem. 1990;8(6):308-13. Clin Physiol Biochem. 1990. PMID: 2132166
5,8,11,14-eicosatetraynoic acid (ETYA), a competitive analogue of arachidonic acid reversibly inhibited human prostate PC3 DNA synthesis at 4 h. ...
5,8,11,14-eicosatetraynoic acid (ETYA), a competitive analogue of arachidonic acid reversib …
Incorporation of 5,8,11,14-eicosatetraynoic acid (ETYA) into cell lipids: competition with arachidonic acid for esterification.
Taylor AS, Morrison AR, Russell JH. Taylor AS, et al. Prostaglandins. 1985 Mar;29(3):449-58. doi: 10.1016/0090-6980(85)90102-9. Prostaglandins. 1985. PMID: 3923563
5,8,11,14-eicosatetraynoic acid (ETYA), a widely used inhibitor of cyclooxygenase and lipoxygenase, inhibited the incorporation of 14C-arachidonic acid into cell lipids of the murine thymoma EL4 whereas oleic acid had no eff …
5,8,11,14-eicosatetraynoic acid (ETYA), a widely used inhibitor of cyclooxygenase and lipoxygenase …
759 results