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1973 1
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24 results

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Page 1
Effect of 4-phenyl-1,2,3,4-tetrahydroisoquinoline on ambulation induced by injection of methamphetamine into the nucleus accumbens in rats.
Tateyama M, Ohta S, Nagao T, Hirobe M, Ono H. Tateyama M, et al. Neuropharmacology. 1993 Mar;32(3):243-8. doi: 10.1016/0028-3908(93)90107-e. Neuropharmacology. 1993. PMID: 8474620
4-Phenyl-1,2,3,4-tetrahydroisoquinoline (4-PTIQ) has previously been shown to have antagonistic properties to methamphetamine in the spinal cord. ...
4-Phenyl-1,2,3,4-tetrahydroisoquinoline (4-PTIQ) has previously been shown to have antagoni …
Pretreatment with nomifensine or nomifensine analogue 4-phenyl-1,2,3,4-tetrahydroisoquinoline augments methamphetamine-induced stereotypical behavior in mice.
Kitanaka J, Kitanaka N, Hall FS, Uhl GR, Asano H, Chatani R, Hayata S, Yokoyama H, Tanaka KI, Nishiyama N, Takemura M. Kitanaka J, et al. Brain Res. 2012 Feb 23;1439:15-26. doi: 10.1016/j.brainres.2011.12.043. Epub 2011 Dec 31. Brain Res. 2012. PMID: 22265332 Free PMC article.
By contrast, the deaminated and demethylated nomifensine analogue 4-phenyl-1,2,3,4-tetrahydroisoquinoline (PTIQ) is reported to have amphetamine-antagonistic properties, as demonstrated by inhibition of methamphetamine (METH)-induc …
By contrast, the deaminated and demethylated nomifensine analogue 4-phenyl-1,2,3,4-tetrahydrois …
4-Hydroxy-2-methyl-4-phenyl-1,2,3,4-tetrahydroisoquinoline (PI-OH): a new potentiator of sympathomimetic amines on the rat anococcygeus muscle.
Ishida Y, Koga N, Nanbu T, Kihara M, Kobayashi S. Ishida Y, et al. Br J Pharmacol. 1988 May;94(1):19-26. doi: 10.1111/j.1476-5381.1988.tb11495.x. Br J Pharmacol. 1988. PMID: 3401637 Free PMC article.
1. The potentiating effects of racemic 4-hydroxy-2-methyl-4-phenyl-1,2,3,4-tetrahydroisoquinoline (PI-OH), cocaine, desipramine and nomifensine on the concentration-response curves of the rat anococcygeus muscle to noradrenaline (N …
1. The potentiating effects of racemic 4-hydroxy-2-methyl-4-phenyl-1,2,3,4-tetrahydroisoquinoli …
Synthesis and pharmacological evaluation of new 1-hydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines as norepinephrine potentiators.
Ikeuchi M, Ikuta M, Hariki M, Ikeuchi M, Maruyama S, Nakase M, Sakamoto K, Yoshioka Y, Yamauchi A, Kihara M. Ikeuchi M, et al. Chem Pharm Bull (Tokyo). 2009 May;57(5):443-5. doi: 10.1248/cpb.57.443. Chem Pharm Bull (Tokyo). 2009. PMID: 19420772 Free article.
4-Hydroxy-2-methyl-4-phenyl-1,2,3,4-tetrahydroisoquinoline (PI-OH) (1a) and its derivatives form a new class of compounds which possess norepinephrine (NE) potentiating activity. ...
4-Hydroxy-2-methyl-4-phenyl-1,2,3,4-tetrahydroisoquinoline (PI-OH) (1a) and its derivatives …
Resolution and absolute stereochemistry of 6,7-dimethoxy-4-phenyl- 1,2,3,4-tetrahydroisoquinoline. The crystal structure of the R-hydrochloride salt form.
Mondeshka D, Angelova I, Stensland B, Werner PE, Ivanov C. Mondeshka D, et al. Acta Chem Scand (Cph). 1992 Jan;46(1):54-9. doi: 10.3891/acta.chem.scand.46-0054. Acta Chem Scand (Cph). 1992. PMID: 1599795
Stereospecific multistep synthesis and resolution of 6,7-dimethoxy-4- phenyl-1,2,3,4-tetrahydroisoquinoline (3) has been achieved from its racemic base. ...
Stereospecific multistep synthesis and resolution of 6,7-dimethoxy-4- phenyl-1,2,3,4-tetrahydro …
Synthesis and pharmacological evaluation of phenolic 2-methyl-4-phenyl-1,2,3,4-tetrahydroisoquinolin-4-ols as a new norepinephrine potentiator.
Kihara M, Ikeuchi M, Kobayashi Y, Nagao Y, Hashizume M, Moritoki H. Kihara M, et al. Drug Des Discov. 1994 Apr;11(3):175-83. Drug Des Discov. 1994. PMID: 7548633
2-Methyl-4-phenyl-1,2,3,4-tetrahydroisoquinoline-4-ol(PI-OH) (2a) and its derivatives form a new class of compounds possessing norepinephrine (NE) potentiating activity. ...
2-Methyl-4-phenyl-1,2,3,4-tetrahydroisoquinoline-4-ol(PI-OH) (2a) and its derivatives form …
Diastereoselective protonation of lactam enolates derived from (R)-phenylglycinol. A novel asymmetric route to 4-phenyl-1,2,3, 4-tetrahydroisoquinolines.
Philippe N, Levacher V, Dupas G, Quéguiner G, Bourguignon J. Philippe N, et al. Org Lett. 2000 Jul 27;2(15):2185-7. doi: 10.1021/ol0057939. Org Lett. 2000. PMID: 10930239
This diastereoselective protonation has been applied to the asymmetric synthesis of (4S)-N-methyl-4-phenyl-1,2,3,4-tetrahydroisoquinoline 9 obtained in up to 97% ee....
This diastereoselective protonation has been applied to the asymmetric synthesis of (4S)-N-methyl-4-phenyl-1,2, …
24 results