In vitro and in silico inhibitory effects of synthetic and natural eugenol derivatives against the NorA efflux pump in Staphylococcus aureus.
Muniz DF, Dos Santos Barbosa CR, de Menezes IRA, de Sousa EO, Pereira RLS, Júnior JTC, Pereira PS, de Matos YMLS, da Costa RHS, de Morais Oliveira-Tintino CD, Coutinho HDM, Filho JMB, Ribeiro de Sousa G, Filho JR, Siqueira-Junior JP, Tintino SR.
Muniz DF, et al.
Food Chem. 2021 Feb 1;337:127776. doi: 10.1016/j.foodchem.2020.127776. Epub 2020 Aug 5.
Food Chem. 2021.
PMID: 32777574
When associated with norfloxacin against the SA 1199B strain, 4-allyl-2,6-dimethoxyphenol eugenol and isoeugenol caused significant reduction in the MIC of the antibiotic, demonstrating synergistic effects. Similar effects were observed when …
When associated with norfloxacin against the SA 1199B strain, 4-allyl-2,6-dimethoxyphenol eugenol and iso …