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Year Number of Results
1980 1
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2010 1
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2023 1
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21 results

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Page 1
PRKAA1 induces aberrant mitophagy in a PINK1/Parkin-dependent manner, contributing to fluoride-induced developmental neurotoxicity.
Tang Y, Zhang J, Hu Z, Xu W, Xu P, Ma Y, Xing H, Niu Q. Tang Y, et al. Ecotoxicol Environ Saf. 2023 Apr 15;255:114772. doi: 10.1016/j.ecoenv.2023.114772. Epub 2023 Mar 14. Ecotoxicol Environ Saf. 2023. PMID: 36924562 Free article.
Meanwhile, phosphoproteomics and western blot analysis showed that NaF treatment enhanced PRKAA1 phosphorylation. Remarkably, the application of both 3-methyladenosine (3-MA; autophagy inhibitor) and dorsomorphin (DM; AMPK inhibitor) suppressed NaF-induced neuronal …
Meanwhile, phosphoproteomics and western blot analysis showed that NaF treatment enhanced PRKAA1 phosphorylation. Remarkably, the applicatio …
miR-let-7f-1 regulates SPARC mediated cisplatin resistance in medulloblastoma cells.
Pannuru P, Dontula R, Khan AA, Herbert E, Ozer H, Chetty C, Lakka SS. Pannuru P, et al. Cell Signal. 2014 Oct;26(10):2193-201. doi: 10.1016/j.cellsig.2014.06.014. Epub 2014 Jul 8. Cell Signal. 2014. PMID: 25014664
We also demonstrate that the autophagy was involved in SPARC expression mediated resistance to cisplatin. Suppression of autophagy by either autophagy inhibitor, 3-methyladenosine (3MA) or Atg5 siRNA enhanced cisplatin sensitivity in SPARC expressed cells. ...
We also demonstrate that the autophagy was involved in SPARC expression mediated resistance to cisplatin. Suppression of autophagy by either …
Valproic acid sensitizes human glioma cells to gefitinib-induced autophagy.
Chang CY, Li JR, Wu CC, Ou YC, Chen WY, Kuan YH, Wang WY, Chen CJ. Chang CY, et al. IUBMB Life. 2015 Nov;67(11):869-79. doi: 10.1002/iub.1445. Epub 2015 Oct 21. IUBMB Life. 2015. PMID: 26488897 Free article.
The augmented consequences were accompanied by the formation of autophagic vacuoles, conversion of microtubule-associated protein-1 light chain 3-II (LC3-II), and degradation of p62. Autophagy inhibitor 3-methyladenosine and chloroquine and genetic silencing of LC3 …
The augmented consequences were accompanied by the formation of autophagic vacuoles, conversion of microtubule-associated protein-1 light ch …
Autophagy promotes aortic adventitial fibrosis via the IL-6/Jak1 signaling pathway in Takayasu's arteritis.
Chen R, Sun Y, Cui X, Ji Z, Kong X, Wu S, Huang Q, Dai X, Zhang S, Ma L, Jiang L. Chen R, et al. J Autoimmun. 2019 May;99:39-47. doi: 10.1016/j.jaut.2019.01.010. Epub 2019 Feb 11. J Autoimmun. 2019. PMID: 30765261
Different stages of autophagy were analyzed by the specific inhibitors, 3-methyladenosine (early stage), hydroxychloroquine sulfate (late stage), and bafilomycin A1 (late stage). ...
Different stages of autophagy were analyzed by the specific inhibitors, 3-methyladenosine (early stage), hydroxychloroquine su …
Oxymatrine Inhibits Homocysteine-Mediated Autophagy via MIF/mTOR Signaling in Human Umbilical Vein Endothelial Cells.
Zhang Y, Zhang Y, Tang J, Zhao S, Li C, Huang YP, Yi M. Zhang Y, et al. Cell Physiol Biochem. 2018;45(5):1893-1903. doi: 10.1159/000487912. Epub 2018 Feb 28. Cell Physiol Biochem. 2018. PMID: 29510402 Free article.
RESULTS: OMT inhibited autophagy, MIF, and mTOR in HUVECs during Hcy exposure, depending on the dose. siRNA-mediated MIF knockdown decreased Hcy-induced autophagy, while administration of 3-methyladenosine and rapamycin showed that they also induce autophagy. ...
RESULTS: OMT inhibited autophagy, MIF, and mTOR in HUVECs during Hcy exposure, depending on the dose. siRNA-mediated MIF knockdown decreased …
Urolithin A-activated autophagy but not mitophagy protects against ischemic neuronal injury by inhibiting ER stress in vitro and in vivo.
Ahsan A, Zheng YR, Wu XL, Tang WD, Liu MR, Ma SJ, Jiang L, Hu WW, Zhang XN, Chen Z. Ahsan A, et al. CNS Neurosci Ther. 2019 Sep;25(9):976-986. doi: 10.1111/cns.13136. Epub 2019 Apr 11. CNS Neurosci Ther. 2019. PMID: 30972969 Free PMC article.
Instead, Uro-A attenuated OGD/R-induced ER stress, which was abolished by 3-methyladenosine. Additionally, neuroprotection was reversed by ER stress inducer. ...
Instead, Uro-A attenuated OGD/R-induced ER stress, which was abolished by 3-methyladenosine. Additionally, neuroprotection was …
DNA damage regulated autophagy modulator 1 recovers the function of apoptosis-stimulating of p53 protein 2 on inducing apoptotic cell death in Huh7.5 cells.
Liu D, Li R, Guo X, Pang L, Zang Y, Liu K, Chen D. Liu D, et al. Oncol Lett. 2018 Jun;15(6):9333-9338. doi: 10.3892/ol.2018.8453. Epub 2018 Apr 10. Oncol Lett. 2018. PMID: 29844830 Free PMC article.
In the present study, ASPP2 overexpression failed to induce apoptotic cell death in the HCC Huh7.5 cell line, but promoted autophagy development by inhibiting AKT/mTOR pathway. Inhibition of autophagy using 3-methyladenosine recovered the function of ASPP2 on induci …
In the present study, ASPP2 overexpression failed to induce apoptotic cell death in the HCC Huh7.5 cell line, but promoted autophagy develop …
Autophagy contributes to gefitinib-induced glioma cell growth inhibition.
Chang CY, Kuan YH, Ou YC, Li JR, Wu CC, Pan PH, Chen WY, Huang HY, Chen CJ. Chang CY, et al. Exp Cell Res. 2014 Sep 10;327(1):102-12. doi: 10.1016/j.yexcr.2014.05.011. Epub 2014 May 27. Exp Cell Res. 2014. PMID: 24876095
The cytostatic consequences were accompanied by autophagy, as evidenced by monodansylcadaverine staining of acidic vesicle formation, conversion of microtubule-associated protein-1 light chain 3-II (LC3-II), degradation of p62, punctate pattern of GFP-LC3, and conversion of GFP-L …
The cytostatic consequences were accompanied by autophagy, as evidenced by monodansylcadaverine staining of acidic vesicle formation, conver …
21 results