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1978 1
1979 1
1980 3
1981 2
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1983 1
1984 1
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1987 5
1988 1
1989 1
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1991 2
1992 1
1993 2
1994 3
1995 1
1996 3
2001 1
2002 3
2004 1
2005 2
2006 3
2007 2
2008 1
2009 4
2010 5
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2013 4
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2016 5
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2020 9
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2023 4
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108 results

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Page 1
2-Amino-1,3,4-thiadiazole as a potential scaffold for promising antimicrobial agents.
Serban G, Stanasel O, Serban E, Bota S. Serban G, et al. Drug Des Devel Ther. 2018 May 31;12:1545-1566. doi: 10.2147/DDDT.S155958. eCollection 2018. Drug Des Devel Ther. 2018. PMID: 29910602 Free PMC article. Review.
The aim of this review was to highlight the main antimicrobial properties exhibited by derivatives possessing 2-amino-1,3,4-thiadiazole moiety. Many of the reported 2-amino-1,3,4-thiadiazole deriv …
The aim of this review was to highlight the main antimicrobial properties exhibited by derivatives possessing 2-amino-1 …
Synthetic Compounds with 2-Amino-1,3,4-Thiadiazole Moiety Against Viral Infections.
Serban G. Serban G. Molecules. 2020 Feb 19;25(4):942. doi: 10.3390/molecules25040942. Molecules. 2020. PMID: 32093125 Free PMC article. Review.
This review provides an overview of the various synthetic compounds containing the 2-amino-1,3,4-thiadiazole moiety that has been evaluated for antiviral activity against several viral strains and could be considered possible prototypes f …
This review provides an overview of the various synthetic compounds containing the 2-amino-1,3,4-thiad …
2-Amino-5-methyl-1,3,4-thiadiazole and 2-amino-5-ethyl-1,3,4-thiadiazole.
Lynch DE. Lynch DE. Acta Crystallogr C. 2001 Oct;57(Pt 10):1201-3. doi: 10.1107/s0108270101011817. Epub 2001 Oct 12. Acta Crystallogr C. 2001. PMID: 11600785
The structures of 2-amino-5-methyl-1,3,4-thiadiazole, C(3)H(5)N(3)S, and 2-amino-5-ethyl-1,3,4-thiadiazole, C(4)H(7)N(3)S, have been determined for comparison with unsubstituted 2-amino-1,3,4-thiadiazole. Despite their different space gro …
The structures of 2-amino-5-methyl-1,3,4-thiadiazole, C(3)H(5)N(3)S, and 2-amino-5-ethyl-1,3,4-thiadiazole, C(4)H(7)N(3)S, have been determi …
A comparison between observed and DFT calculations on structure of 5-(4-chlorophenyl)-2-amino-1,3,4-thiadiazole.
Kerru N, Gummidi L, Bhaskaruni SVHS, Maddila SN, Singh P, Jonnalagadda SB. Kerru N, et al. Sci Rep. 2019 Dec 17;9(1):19280. doi: 10.1038/s41598-019-55793-5. Sci Rep. 2019. PMID: 31848439 Free PMC article.
The crystal and molecular structure of 5-(4-chlorophenyl)-2-amino-1,3,4-thiadiazole 3 was reported, which was characterized by various spectroscopic techniques (FT-IR, NMR and HRMS) and single-crystal X-ray diffraction. ...
The crystal and molecular structure of 5-(4-chlorophenyl)-2-amino-1,3,4-thiadiazole 3 was reported …
Antiparasitic Behavior of Trifluoromethylated Pyrazole 2-Amino-1,3,4-thiadiazole Hybrids and Their Analogues: Synthesis and Structure-Activity Relationship.
Camargo JDNA, Pianoski KE, Dos Santos MG, Lazarin-Bidóia D, Volpato H, Moura S, Nakamura CV, Rosa FA. Camargo JDNA, et al. Front Pharmacol. 2020 Oct 7;11:591570. doi: 10.3389/fphar.2020.591570. eCollection 2020. Front Pharmacol. 2020. PMID: 33117181 Free PMC article.
A series of trifluoromethylated pyrazole thiosemicarbazone, trifluromethylated pyrazole isothiosemicarbazone, and trifluoromethylated pyrazole 2-amino-1,3,4-thiadiazole hybrids were synthesized and evaluated in vitro against the promastig …
A series of trifluoromethylated pyrazole thiosemicarbazone, trifluromethylated pyrazole isothiosemicarbazone, and trifluoromethylated pyrazo …
A Novel Approach to the Synthesis of 1,3,4-Thiadiazole-2-amine Derivatives.
Kokovina TS, Gadomsky SY, Terentiev AA, Sanina NA. Kokovina TS, et al. Molecules. 2021 Aug 25;26(17):5159. doi: 10.3390/molecules26175159. Molecules. 2021. PMID: 34500593 Free PMC article.
It was found that, in the presence of PPE, the reaction between the thiosemicarbazide and carboxylic acid proceeds in one-pot through three steps with the formation of corresponding 2-amino-1,3,4-thiadiazole. Using the developed approach …
It was found that, in the presence of PPE, the reaction between the thiosemicarbazide and carboxylic acid proceeds in one-pot through three …
Aminothiadiazoles.
Hill DL. Hill DL. Cancer Chemother Pharmacol. 1980;4(4):215-20. doi: 10.1007/BF00255264. Cancer Chemother Pharmacol. 1980. PMID: 7002341 Review.
2-Amino-1,3,4-thiadiazole (ATDA) and some of its analogs have antitumor, uricogenic, and teratogenic activity. ...
2-Amino-1,3,4-thiadiazole (ATDA) and some of its analogs have antitumor, uricogenic, and teratogen …
Synthesis of a Series of Novel 2-Amino-5-substituted 1,3,4-oxadiazole and 1,3,4-thiadiazole Derivatives as Potential Anticancer, Antifungal and Antibacterial Agents.
Pham EC, Truong TN, Dong NH, Vo DD, Hong Do TT. Pham EC, et al. Med Chem. 2022;18(5):558-573. doi: 10.2174/1573406417666210803170637. Med Chem. 2022. PMID: 34344293
OBJECTIVE: The objective of the present study was to prepare the 5-substituted 2-amino-1,3,4- oxadiazole and 2-amino-1,3,4-thiadiazole derivatives and evaluate their potential anticancer, antibacterial and antifungal activities. ...
OBJECTIVE: The objective of the present study was to prepare the 5-substituted 2-amino-1,3,4- oxadiazole and 2-amino-1, …
108 results