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Large-scale synthesis of the bifunctional chelating agent 2-(p-nitrobenzyl)-1,4,7,10-tetraazacyclododecane-N,N',N'',N'''-tetr aacetic acid, and the determination of its enantiomeric purity by chiral chromatography.
Renn O, Meares CF. Renn O, et al. Bioconjug Chem. 1992 Nov-Dec;3(6):563-9. doi: 10.1021/bc00018a017. Bioconjug Chem. 1992. PMID: 1463787
Chelators that can hold radiometals like 111In, 67Ga, and 90Y with high stability under these conditions are essential for radiotherapy or immunoscintigraphy. 2-(p-Nitrobenzyl)-1,4,7,10-tetraazacyclododecane- N,N',N'',N'''-tetraacetic acid (nitrobenzyl-DOTA) is one of the …
Chelators that can hold radiometals like 111In, 67Ga, and 90Y with high stability under these conditions are essential for radiotherapy or i …