Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1997 11
1998 31
1999 35
2000 38
2001 39
2002 46
2003 30
2004 30
2005 24
2006 40
2007 33
2008 34
2009 25
2010 19
2011 15
2012 20
2013 21
2014 14
2015 13
2016 13
2017 17
2018 11
2019 7
2020 18
2021 3
2022 4
2023 2
2024 1

Text availability

Article attribute

Article type

Publication date

Search Results

546 results

Results by year

Filters applied: . Clear all
Page 1
From MIF-1 to endomorphin: the Tyr-MIF-1 family of peptides.
Pan W, Kastin AJ. Pan W, et al. Peptides. 2007 Dec;28(12):2411-34. doi: 10.1016/j.peptides.2007.10.006. Epub 2007 Oct 18. Peptides. 2007. PMID: 17988762 Review.
Tyr-W-MIF-1 (Tyr-Pro-Trp-Gly-NH(2)) is an even more selective ligand for the mu receptor, leading to the discovery of two more Tyr-Pro tetrapeptides that have the highest specificity and affinity for this site. These are the endomorphins: endomorphin-1 is Tyr-Pro-Tr …
Tyr-W-MIF-1 (Tyr-Pro-Trp-Gly-NH(2)) is an even more selective ligand for the mu receptor, leading to the discovery of two more Tyr-Pro tetra …
The antinociceptive properties of endomorphin-1 and endomorphin-2 in the mouse.
Tseng LF. Tseng LF. Jpn J Pharmacol. 2002 Jul;89(3):216-20. doi: 10.1254/jjp.89.216. Jpn J Pharmacol. 2002. PMID: 12184724 Free article. Review.
Two highly selective mu-opioid receptor agonists, endomorphin-1 (EM-1) and endomorphin-2 (EM-2), have been identified and postulated to be endogenous mu-opioid receptor ligands. ...
Two highly selective mu-opioid receptor agonists, endomorphin-1 (EM-1) and endomorphin-2 (EM-2), have been identified and post …
Endomorphin-induced motivational effect: differential mechanism of endomorphin-1 and endomorphin-2.
Narita M, Ozaki S, Suzuki T. Narita M, et al. Jpn J Pharmacol. 2002 Jul;89(3):224-8. doi: 10.1254/jjp.89.224. Jpn J Pharmacol. 2002. PMID: 12184726 Free article. Review.
The newly discovered endogenous mu-opioid receptor (MOP-R) ligands endomorphin-1 (EM-1) and -2 (EM-2) exhibit the highest specificity and affinity for the MOP-R of any endogenous substance so far described in the mammalian nervous system. ...
The newly discovered endogenous mu-opioid receptor (MOP-R) ligands endomorphin-1 (EM-1) and -2 (EM-2) exhibit the highest spec …
Differential antinociceptive effects induced by intrathecally-administered endomorphin-1 and endomorphin-2 in mice.
Sakurada S, Hayashi T, Yuhki M. Sakurada S, et al. Jpn J Pharmacol. 2002 Jul;89(3):221-3. doi: 10.1254/jjp.89.221. Jpn J Pharmacol. 2002. PMID: 12184725 Free article. Review.
Two highly selective mu-opioid receptor (MOP-R) agonists, endomorphin-1 (EM-1) and endomorphin-2 (EM-2), have been identified and postulated to be endogenous ligands for MOP-R. ...
Two highly selective mu-opioid receptor (MOP-R) agonists, endomorphin-1 (EM-1) and endomorphin-2 (EM-2), have been identified …
Original endomorphin-1 analogues exhibit good analgesic effects.
Wu Y, Zhao X, Gan Y, Zhang X, Wei H, Wang L, Liang X, Gao X, Liu Y, Hu J, Wang Y. Wu Y, et al. Bioorg Med Chem Lett. 2017 Apr 1;27(7):1557-1560. doi: 10.1016/j.bmcl.2017.02.034. Epub 2017 Feb 20. Bioorg Med Chem Lett. 2017. PMID: 28256374
A new class of endomorphin-1 analogues was synthesized by combining successful chemical modifications including N-terminal guanidino modification, Phe(4) was chlorinated, D-Ala-Gly Substituted L-Pro(2). ...
A new class of endomorphin-1 analogues was synthesized by combining successful chemical modifications including N-terminal gua …
Strategies to Improve Bioavailability and In Vivo Efficacy of the Endogenous Opioid Peptides Endomorphin-1 and Endomorphin-2.
De Marco R, Janecka A. De Marco R, et al. Curr Top Med Chem. 2015;16(2):141-55. doi: 10.2174/1568026615666150817103635. Curr Top Med Chem. 2015. PMID: 26279081 Review.
For these reasons, there is currently renewed interest in the design and assay of modified versions of the potent endogenous opioid peptides endomorphin-1 and endomorphin-2. This review presents a selection of the strategies directed at preparing highly stable pepti …
For these reasons, there is currently renewed interest in the design and assay of modified versions of the potent endogenous opioid peptides …
Micelle-associated endomorphin-1 has ability to bind copper in the oxidation state either Cu(II) or Cu(I).
Kuwana Y, Ashizawa Y, Ajima M, Nomura T, Kakeno M, Hirai S, Miura T. Kuwana Y, et al. Arch Biochem Biophys. 2022 Sep 30;727:109305. doi: 10.1016/j.abb.2022.109305. Epub 2022 May 31. Arch Biochem Biophys. 2022. PMID: 35660411
In the present study, interactions of the endogenous opioid peptide endomorphin-1 (EM1, Tyr-Pro-Trp-Phe-NH(2)) with ionic copper were investigated. ...
In the present study, interactions of the endogenous opioid peptide endomorphin-1 (EM1, Tyr-Pro-Trp-Phe-NH(2)) with ionic copp …
The antinociceptive effects of endomorphin-1 and endomorphin-2 in diabetic mice.
Kamei J, Zushida K, Ohsawa M, Nagase H. Kamei J, et al. Eur J Pharmacol. 2000 Mar 10;391(1-2):91-6. doi: 10.1016/s0014-2999(00)00049-2. Eur J Pharmacol. 2000. PMID: 10720639
However, these micro-opioid receptor antagonists had no significant effect on the antinociceptive effect of endomorphin-1 in diabetic mice. The antinociception induced by endomorphin-1 in diabetic mice was significantly reduced by naltrindole and 7-ben …
However, these micro-opioid receptor antagonists had no significant effect on the antinociceptive effect of endomorphin-1 in d …
The antitussive effects of endomorphin-1 and endomorphin-2 in mice.
Kamei J, Morita K, Saitoh A, Nagase H. Kamei J, et al. Eur J Pharmacol. 2003 Apr 25;467(1-3):219-22. doi: 10.1016/s0014-2999(03)01634-0. Eur J Pharmacol. 2003. PMID: 12706478
The antitussive effects of endomorphin-1 and endomorphin-2, endogenous mu-opioid receptor agonists, on capsaicin-induced coughs were examined in mice. Endomorphin-2, at doses of 3, 10 and 30 microg, i.c.v., dose-dependently inhibited the number of capsaicin-induced …
The antitussive effects of endomorphin-1 and endomorphin-2, endogenous mu-opioid receptor agonists, on capsaicin-induced cough …
546 results