Diphenylarsinic Acid Induced Activation of Cultured Rat Cerebellar Astrocytes: Phosphorylation of Mitogen-Activated Protein Kinases, Upregulation of Transcription Factors, and Release of Brain-Active Cytokines.
Negishi T, Matsumoto M, Kojima M, Asai R, Kanehira T, Sakaguchi F, Takahata K, Arakaki R, Aoyama Y, Yoshida H, Yoshida K, Yukawa K, Tashiro T, Hirano S.
Negishi T, et al.
Toxicol Sci. 2016 Mar;150(1):74-83. doi: 10.1093/toxsci/kfv310. Epub 2015 Dec 8.
Toxicol Sci. 2016.
PMID: 26645585
Diphenylarsinic acid (DPAA) was detected as the primary compound responsible for the arsenic poisoning that occurred in Kamisu, Ibaraki, Japan, where people using water from a well that was contaminated with a high level of arsenic developed neurological (mostly cer …
Diphenylarsinic acid (DPAA) was detected as the primary compound responsible for the arsenic poisoning that occurred in Kamisu …