Autophagy deficiency abolishes liver mitochondrial DNA segregation.
Tostes K, Dos Santos AC, Alves LO, Bechara LRG, Marascalchi R, Macabelli CH, Grejo MP, Festuccia WT, Gottlieb RA, Ferreira JCB, Chiaratti MR.
Tostes K, et al.
Autophagy. 2022 Oct;18(10):2397-2408. doi: 10.1080/15548627.2022.2038501. Epub 2022 Feb 27.
Autophagy. 2022.
PMID: 35220898
Free PMC article.
Considering that NZB/BINJ and C57BL/6N mtDNAs have a level of divergence comparable to that between human Eurasian and African mtDNAs, these findings have potential implications for humans, including the safe use of mitochondrial replacement therapy.Abbreviations: Apob: apolipopr …
Considering that NZB/BINJ and C57BL/6N mtDNAs have a level of divergence comparable to that between human Eurasian and African mtDNAs, these …