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1993 | 1 |
1995 | 1 |
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Pharmacological study of 14 beta-(thioglycolamido)-7,8-dihydro-N(cyclopropylmethyl)-normor phinone (N-CPM-TAMO).
J Pharmacol Exp Ther. 1993 Mar;264(3):1021-7.
J Pharmacol Exp Ther. 1993.
PMID: 7680715
The antagonism by N-CPM-TAMO lasted up to 48 hr, with a maximal effect at 24 hr after i.c.v. administration. ...These data indicate that N-CPM-TAMO is a mu-selective, long-term antagonist.(ABSTRACT TRUNCATED AT 250 WORDS)...
The antagonism by N-CPM-TAMO lasted up to 48 hr, with a maximal effect at 24 hr after i.c.v. administration. ...These d …
Preventing morphine antinociceptive tolerance by irreversible mu opioid antagonists before the onset of their antagonism.
Jiang Q, Seyed-Mozaffari A, Sebastian A, Archer S, Bidlack JM.
Jiang Q, et al.
J Pharmacol Exp Ther. 1995 May;273(2):680-8.
J Pharmacol Exp Ther. 1995.
PMID: 7752070
All opioids were given by i.c.v. administration. The irreversible antagonists, beta-FNA (20 nmol), N-CPM-TAMO (0.5 nmol) and N-CPM-MET-CAMO (1 nmol) did not produce any antagonism of morphine-induced analgesia until at least 8 hr after administration. Pretrea …
All opioids were given by i.c.v. administration. The irreversible antagonists, beta-FNA (20 nmol), N-CPM-TAMO (0.5 nmol …
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