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From alkyl halides to alkyltrifluoromethyls using bromine trifluoride.
Hagooly A, Ben-David I, Rozen S. Hagooly A, et al. J Org Chem. 2002 Nov 29;67(24):8430-4. doi: 10.1021/jo026128b. J Org Chem. 2002. PMID: 12444621
Under the right conditions, bromine trifluoride can be a useful tool for generating new types of reactions and compounds. ...
Under the right conditions, bromine trifluoride can be a useful tool for generating new types of reactions and compounds. ...
Synthesis of difluoroaryldioxoles using BrF3.
Hagooly Y, Welch MJ, Rozen S. Hagooly Y, et al. Org Biomol Chem. 2011 Feb 7;9(3):902-5. doi: 10.1039/c0ob00571a. Epub 2010 Dec 3. Org Biomol Chem. 2011. PMID: 21127811
The latter were reacted for a short time with commercially available bromine trifluoride, producing potentially biologically important difluoroaryldioxoles in moderate to high yields....
The latter were reacted for a short time with commercially available bromine trifluoride, producing potentially biologically i …
Eighteenth Interim Report of the Committee onAcute Exposure Guideline Levels.
National Research Council (US) Committee on Acute Exposure Guideline Levels. National Research Council (US) Committee on Acute Exposure Guideline Levels. Washington (DC): National Academies Press (US); 2010. Washington (DC): National Academies Press (US); 2010. PMID: 25032395 Free Books & Documents. Review.
It summarizes the committee's conclusions and recommendations for improving NAC's AEGL documents for 25 chemicals: allyl alcohol, bis-chloromethyl ether, chloromethyl methyl ether, bromine pentafluoride, bromine trifluoride, chlorine pentafluoride, carbon tetrachlor …
It summarizes the committee's conclusions and recommendations for improving NAC's AEGL documents for 25 chemicals: allyl alcohol, bis-chloro …
The Interhalogen Cations [Br2 F5 ]+ and [Br3 F8 ].
Ivlev SI, Karttunen AJ, Buchner MR, Conrad M, Kraus F. Ivlev SI, et al. Angew Chem Int Ed Engl. 2018 Oct 26;57(44):14640-14644. doi: 10.1002/anie.201803708. Epub 2018 May 30. Angew Chem Int Ed Engl. 2018. PMID: 29719105
Toward the synthesis of the rare N-(trifluoromethyl)amides and the N-(difluoromethylene)-N-(trifluoromethyl)amines [RN(CF3)CF2R'] using BrF3.
Hagooly Y, Gatenyo J, Hagooly A, Rozen S. Hagooly Y, et al. J Org Chem. 2009 Nov 20;74(22):8578-82. doi: 10.1021/jo901560b. J Org Chem. 2009. PMID: 19835360
The starting materials are the easily available isothiocyanates, and the fluorinating reagent is the commercially available bromine trifluoride. The reaction is performed under mild conditions, and the fluorinated amides and amines are produced in moderate to high y …
The starting materials are the easily available isothiocyanates, and the fluorinating reagent is the commercially available bromine
Attaching the fluorine atom to organic molecules using BrF3 and other reagents directly derived from F2.
Rozen S. Rozen S. Acc Chem Res. 2005 Oct;38(10):803-12. doi: 10.1021/ar040270c. Acc Chem Res. 2005. PMID: 16231876
., AcOF). All three categories are represented in this Account. Bromine trifluoride, although commercially available, can be readily made from the elements and is a very good source for naked nucleophilic fluoride ions. ...
., AcOF). All three categories are represented in this Account. Bromine trifluoride, although commercially available, can be r …
From azides to nitriles. A novel fast transformation made possible by BrF3.
Sasson R, Rozen S. Sasson R, et al. Org Lett. 2005 May 26;7(11):2177-9. doi: 10.1021/ol050523h. Org Lett. 2005. PMID: 15901163
Various alkyl and aryl azides, readily obtained from halides or alcohols, were transformed into the corresponding nitriles using bromine trifluoride in moderate to good yields. The reaction is general and gives positive results with aliphatic, aromatic, cyclic, and …
Various alkyl and aryl azides, readily obtained from halides or alcohols, were transformed into the corresponding nitriles using bromine
14 results