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Table representation of search results timeline featuring number of search results per year.
Year | Number of Results |
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2014 | 1 |
2017 | 1 |
2018 | 1 |
2022 | 1 |
2024 | 0 |
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Discovery of the CCR1 antagonist, BMS-817399, for the treatment of rheumatoid arthritis.
J Med Chem. 2014 Sep 25;57(18):7550-64. doi: 10.1021/jm5003167. Epub 2014 Sep 3.
J Med Chem. 2014.
PMID: 25101488
Modulation of PXR transactivation has revealed the selective and orally bioavailable CCR1 antagonist BMS-817399 (29), which entered clinical trials for the treatment of rheumatoid arthritis....
Modulation of PXR transactivation has revealed the selective and orally bioavailable CCR1 antagonist BMS-817399 (29), which en …
Moisture-Induced Amorphous Phase Separation of Amorphous Solid Dispersions: Molecular Mechanism, Microstructure, and Its Impact on Dissolution Performance.
Chen H, Pui Y, Liu C, Chen Z, Su CC, Hageman M, Hussain M, Haskell R, Stefanski K, Foster K, Gudmundsson O, Qian F.
Chen H, et al.
J Pharm Sci. 2018 Jan;107(1):317-326. doi: 10.1016/j.xphs.2017.10.028. Epub 2017 Oct 26.
J Pharm Sci. 2018.
PMID: 29107047
The objective of this study was to investigate: (1) the phase behavior of amorphous solid dispersions composed of a poorly water-soluble drug with extremely low crystallization propensity, BMS-817399, and PVP, following exposure to different relative humidity (RH), …
The objective of this study was to investigate: (1) the phase behavior of amorphous solid dispersions composed of a poorly water-soluble dru …
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Identification of potential drug targets for vascular dementia and carotid plaques by analyzing underlying molecular signatures shared by them.
Shu J, Ren Y, Tan W, Wei W, Zhang L, Chang J.
Shu J, et al.
Front Aging Neurosci. 2022 Oct 3;14:967146. doi: 10.3389/fnagi.2022.967146. eCollection 2022.
Front Aging Neurosci. 2022.
PMID: 36262886
Free PMC article.
The drug-gene interaction analysis showed that four drugs (avacopan, CCX354, BMS-817399, and ASK-8007) could be potential drugs for VaD and carotid atherosclerotic plaques treatment. ...
The drug-gene interaction analysis showed that four drugs (avacopan, CCX354, BMS-817399, and ASK-8007) could be potential drug …
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