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Page 1
Arachidin-1, a Prenylated Stilbenoid from Peanut, Induces Apoptosis in Triple-Negative Breast Cancer Cells.
Mohammadhosseinpour S, Ho LC, Fang L, Xu J, Medina-Bolivar F. Mohammadhosseinpour S, et al. Int J Mol Sci. 2022 Jan 20;23(3):1139. doi: 10.3390/ijms23031139. Int J Mol Sci. 2022. PMID: 35163062 Free PMC article.
The goal of this study was to assess cytotoxicity and apoptosis mechanisms of prenylated stilbenoids in TNBC cells. The prenylated stilbenoids arachidin-1 (A-1) and arachidin-3 (A-3) are analogs of resveratrol (RES) produced in peanut upon biotic stress. ...
The goal of this study was to assess cytotoxicity and apoptosis mechanisms of prenylated stilbenoids in TNBC cells. The prenylated stilbenoi …
Arachidin-1, a Prenylated Stilbenoid from Peanut, Enhances the Anticancer Effects of Paclitaxel in Triple-Negative Breast Cancer Cells.
Mohammadhosseinpour S, Weaver A, Sudhakaran M, Ho LC, Le T, Doseff AI, Medina-Bolivar F. Mohammadhosseinpour S, et al. Cancers (Basel). 2023 Jan 7;15(2):399. doi: 10.3390/cancers15020399. Cancers (Basel). 2023. PMID: 36672351 Free PMC article.
To this end, the cytotoxic effects of the prenylated stilbenoids arachidin-1 (A-1) and arachidin-3 (A-3), and non-prenylated resveratrol (RES) were evaluated in human TNBC cell lines as potential adjuvants for paclitaxel (Pac). ...
To this end, the cytotoxic effects of the prenylated stilbenoids arachidin-1 (A-1) and arachidin-3 (A-3), and non-prenylated r …
Induction of the Prenylated Stilbenoids Arachidin-1 and Arachidin-3 and Their Semi-Preparative Separation and Purification from Hairy Root Cultures of Peanut (Arachis hypogaea L.).
Sharma AR, Gajurel G, Ahmed I, Roedel K, Medina-Bolivar F. Sharma AR, et al. Molecules. 2022 Sep 19;27(18):6118. doi: 10.3390/molecules27186118. Molecules. 2022. PMID: 36144847 Free PMC article.
Prenylated stilbenoids such as arachidin-1 and arachidin-3 are stilbene derivatives that exhibit multiple pharmacological activities. ...Similarly, cyclodextrin combined with methyl jasmonate selectively enhanced arachidin-3 yield (178.2 6.8 mg/L), which was 5.5-fol …
Prenylated stilbenoids such as arachidin-1 and arachidin-3 are stilbene derivatives that exhibit multiple pharmacological acti …
Peanut arachidin-1 enhances Nrf2-mediated protective mechanisms against TNF-alpha-induced ICAM-1 expression and NF-kappaB activation in endothelial cells.
Chen LG, Zhang YQ, Wu ZZ, Hsieh CW, Chu CS, Wung BS. Chen LG, et al. Int J Mol Med. 2018 Jan;41(1):541-547. doi: 10.3892/ijmm.2017.3238. Epub 2017 Nov 7. Int J Mol Med. 2018. PMID: 29115410
Arachidin-1 [trans-4-(3-methyl-1-butenyl)-3,5,3',4'-tetrahydroxystilbene] is a polyphenol produced by peanut kernels during germination. ...Following arachidin-1 pretreatment, the H2O2-induced generation of reactive oxygen species was reduced. ...
Arachidin-1 [trans-4-(3-methyl-1-butenyl)-3,5,3',4'-tetrahydroxystilbene] is a polyphenol produced by peanut kernels during ge …
Purification of resveratrol, arachidin-1, and arachidin-3 from hairy root cultures of peanut (Arachis hypogaea) and determination of their antioxidant activity and cytotoxicity.
Abbott JA, Medina-Bolivar F, Martin EM, Engelberth AS, Villagarcia H, Clausen EC, Carrier DJ. Abbott JA, et al. Biotechnol Prog. 2010 Sep-Oct;26(5):1344-51. doi: 10.1002/btpr.454. Biotechnol Prog. 2010. PMID: 20623593
Antioxidant stilbenoids, such as resveratrol, arachidin-1, and arachidin-3, have demonstrated beneficial effects on human health. ...In a single run of CPC, resveratrol, arachidin-1, and arachidin-3 were separated to a purity of 97.1%, 97.0%, and 91.8% …
Antioxidant stilbenoids, such as resveratrol, arachidin-1, and arachidin-3, have demonstrated beneficial effects on human heal …
Arachidin-1, a peanut stilbenoid, induces programmed cell death in human leukemia HL-60 cells.
Huang CP, Au LC, Chiou RY, Chung PC, Chen SY, Tang WC, Chang CL, Fang WH, Lin SB. Huang CP, et al. J Agric Food Chem. 2010 Dec 8;58(23):12123-9. doi: 10.1021/jf102993j. Epub 2010 Nov 10. J Agric Food Chem. 2010. PMID: 21067217
The stilbenoids, arachidin-1 (Ara-1), arachidin-3, isopentadienylresveratrol, and resveratrol, have been isolated from germinating peanut kernels and characterized as antioxidant and anti-inflammatory agents. ...
The stilbenoids, arachidin-1 (Ara-1), arachidin-3, isopentadienylresveratrol, and resveratrol, have been isolated from germina …
Effect of peanut stilbenoids, arachidin-1 and arachidin-3, on Streptococcus mutans growth and acid production.
Reed KB, Pruitt E, Hansa Raj KC, Sharma AR, Medina-Bolivar F, Shields RC. Reed KB, et al. Nat Prod Res. 2024 Jan 15:1-9. doi: 10.1080/14786419.2024.2302316. Online ahead of print. Nat Prod Res. 2024. PMID: 38225899
Here we sought to determine if the addition of a prenyl group to the stilbene backbone increased anti-S. mutans activities. Two prenylated stilbenes, arachidin-1 and arachidin-3, were produced using a peanut hairy root production system. Compared to resveratrol and …
Here we sought to determine if the addition of a prenyl group to the stilbene backbone increased anti-S. mutans activities. Two prenylated s …
Production and antimicrobial activity of trans-resveratrol, trans-arachidin-1 and trans-arachidin-3 from elicited peanut hairy root cultures in shake flasks compared with bioreactors.
Eungsuwan N, Chayjarung P, Pankam J, Pilaisangsuree V, Wongshaya P, Kongbangkerd A, Sriphannam C, Limmongkon A. Eungsuwan N, et al. J Biotechnol. 2021 Jan 20;326:28-36. doi: 10.1016/j.jbiotec.2020.12.006. Epub 2020 Dec 28. J Biotechnol. 2021. PMID: 33359213
Enhanced production of stilbene compounds such as trans-resveratrol, trans-arachidin-1 and trans-arachidin-3 was achieved using an elicitor treatment procedure. ...The highest ABTS and FRAP antioxidant activity, and levels of total phenolic compounds, trans-arach …
Enhanced production of stilbene compounds such as trans-resveratrol, trans-arachidin-1 and trans-arachidin-3 was achieved usin …
Enhanced Production of Resveratrol, Piceatannol, Arachidin-1, and Arachidin-3 in Hairy Root Cultures of Peanut Co-treated with Methyl Jasmonate and Cyclodextrin.
Yang T, Fang L, Nopo-Olazabal C, Condori J, Nopo-Olazabal L, Balmaceda C, Medina-Bolivar F. Yang T, et al. J Agric Food Chem. 2015 Apr 22;63(15):3942-50. doi: 10.1021/jf5050266. Epub 2015 Apr 10. J Agric Food Chem. 2015. PMID: 25837778
Peanut (Arachis hypogaea) produces stilbenoids upon exposure to abiotic and biotic stresses. Among these compounds, the prenylated stilbenoids arachidin-1 and arachidin-3 have shown diverse biological activities with potential applications in human health. ...The av …
Peanut (Arachis hypogaea) produces stilbenoids upon exposure to abiotic and biotic stresses. Among these compounds, the prenylated stilbenoi …
Biosynthesis enhancement and antioxidant and anti-inflammatory activities of peanut (Arachis hypogaea L.) arachidin-1, arachidin-3, and isopentadienylresveratrol.
Chang JC, Lai YH, Djoko B, Wu PL, Liu CD, Liu YW, Chiou RY. Chang JC, et al. J Agric Food Chem. 2006 Dec 27;54(26):10281-7. doi: 10.1021/jf0620766. J Agric Food Chem. 2006. PMID: 17177571
When peanut kernels (Tainan 14, a Spanish cultivar) were imbibed, incubated 3 days for germination, sliced, incubated with artificial aeration, periodically sampled, lyophilized, extracted with methanol, and subjected to reverse-phase HPLC analysis, four major fractionations were …
When peanut kernels (Tainan 14, a Spanish cultivar) were imbibed, incubated 3 days for germination, sliced, incubated with artificial aerati …
26 results