Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1973 1
2000 2
2002 1
2003 1
2005 1
2006 3
2007 5
2008 6
2009 1
2010 3
2011 5
2012 7
2013 9
2014 10
2015 10
2016 8
2017 9
2018 14
2019 15
2020 16
2021 12
2022 14
2023 13
2024 2

Text availability

Article attribute

Article type

Publication date

Search Results

142 results

Results by year

Filters applied: . Clear all
Page 1
Structure Properties, Acquisition Protocols, and Biological Activities of Oleuropein Aglycone.
Xu F, Li Y, Zheng M, Xi X, Zhang X, Han C. Xu F, et al. Front Chem. 2018 Aug 13;6:239. doi: 10.3389/fchem.2018.00239. eCollection 2018. Front Chem. 2018. PMID: 30151359 Free PMC article. Review.
This paper summarizes the structure properties, acquisition protocols, and biological activities of oleuropein aglycone. There are three hydrolytic methods used to obtain oleuropein aglycone from oleuropein-enzymatic hydrolysis, acid hydrolysis, and ac …
This paper summarizes the structure properties, acquisition protocols, and biological activities of oleuropein aglycone. There …
Potential Therapeutic Effects of Oleuropein Aglycone in Alzheimer's Disease.
Martorell M, Forman K, Castro N, Capó X, Tejada S, Sureda A. Martorell M, et al. Curr Pharm Biotechnol. 2016;17(11):994-1001. doi: 10.2174/1389201017666160725120656. Curr Pharm Biotechnol. 2016. PMID: 27455905 Review.
In the current work, available literature on oleuropein aglycone effects as antioxidant and inhibitor of amyloid deposits in AD is reviewed. Moreover, we discuss the chemistry, food sources and bioavailability of oleuropein aglycone....
In the current work, available literature on oleuropein aglycone effects as antioxidant and inhibitor of amyloid deposits in A …
Benefit of Oleuropein Aglycone for Alzheimer's Disease by Promoting Autophagy.
Cordero JG, García-Escudero R, Avila J, Gargini R, García-Escudero V. Cordero JG, et al. Oxid Med Cell Longev. 2018 Feb 20;2018:5010741. doi: 10.1155/2018/5010741. eCollection 2018. Oxid Med Cell Longev. 2018. PMID: 29675133 Free PMC article. Review.
The benefits of the Mediterranean diet on Alzheimer's disease and cognitive impairment are well known, attributing this effect to several polyphenols, such as oleuropein aglycone (OLE), present in extra virgin olive oil. OLE is able to induce autophagy, achieving a …
The benefits of the Mediterranean diet on Alzheimer's disease and cognitive impairment are well known, attributing this effect to several po …
Oleuropein aglycone and polyphenols from olive mill waste water ameliorate cognitive deficits and neuropathology.
Pantano D, Luccarini I, Nardiello P, Servili M, Stefani M, Casamenti F. Pantano D, et al. Br J Clin Pharmacol. 2017 Jan;83(1):54-62. doi: 10.1111/bcp.12993. Epub 2016 May 21. Br J Clin Pharmacol. 2017. PMID: 27131215 Free PMC article. Review.
AIM: In TgCRND8 (Tg) mice we checked the dose-response effect of diet supplementation with oleuropein aglycone (OLE) at 12.5 or 0.5 mg kg(-1) of diet. We also studied the effects of dietary intake of the mix of polyphenols present in olive mill waste water administe …
AIM: In TgCRND8 (Tg) mice we checked the dose-response effect of diet supplementation with oleuropein aglycone (OLE) at 12.5 o …
Oleuropein: Chemistry, extraction techniques and nutraceutical perspectives-An update.
Khalil AA, Rahman MM, Rauf A, Islam MR, Manna SJ, Khan AA, Ullah S, Akhtar MN, Aljohani ASM, Abdulmonem WA, Simal-Gandara J. Khalil AA, et al. Crit Rev Food Sci Nutr. 2023 Jun 5:1-22. doi: 10.1080/10408398.2023.2218495. Online ahead of print. Crit Rev Food Sci Nutr. 2023. PMID: 37272499 Review.
Various parts of olive tree are rich source of diverse bioactive compounds such as Apigenin, elenolic acid, Hydroxytyrosol, Ligstroside, Oleoside, Oleuropein, Oleuropein aglycone, Tyrosol, etc. Among these, oleuropein, a secoiridoid is predominantly found in olive l …
Various parts of olive tree are rich source of diverse bioactive compounds such as Apigenin, elenolic acid, Hydroxytyrosol, Ligstroside, Ole …
Oleuropein aglycone: A polyphenol with different targets against amyloid toxicity.
Leri M, Oropesa-Nuñez R, Canale C, Raimondi S, Giorgetti S, Bruzzone E, Bellotti V, Stefani M, Bucciantini M. Leri M, et al. Biochim Biophys Acta Gen Subj. 2018 Jun;1862(6):1432-1442. doi: 10.1016/j.bbagen.2018.03.023. Epub 2018 Mar 21. Biochim Biophys Acta Gen Subj. 2018. PMID: 29571746 Free article.
Oleuropein aglycone and hydroxytyrosol interfere differently with toxic Abeta(1-42) aggregation.
Leri M, Natalello A, Bruzzone E, Stefani M, Bucciantini M. Leri M, et al. Food Chem Toxicol. 2019 Jul;129:1-12. doi: 10.1016/j.fct.2019.04.015. Epub 2019 Apr 14. Food Chem Toxicol. 2019. PMID: 30995514
Oleuropein aglycone (OleA), the most abundant polyphenol in extra virgin olive oil (EVOO), and Hydroxythyrosol (HT), the OleA main metabolite, have attracted our interest due to their multitarget effects, including the interference with amyloid aggregation path. ...
Oleuropein aglycone (OleA), the most abundant polyphenol in extra virgin olive oil (EVOO), and Hydroxythyrosol (HT), the OleA …
Anti-Inflammatory Effects of Olive Leaf Extract and Its Bioactive Compounds Oleacin and Oleuropein-Aglycone on Senescent Endothelial and Small Airway Epithelial Cells.
Silvestrini A, Giordani C, Bonacci S, Giuliani A, Ramini D, Matacchione G, Sabbatinelli J, Di Valerio S, Pacetti D, Procopio AD, Procopio A, Rippo MR. Silvestrini A, et al. Antioxidants (Basel). 2023 Jul 28;12(8):1509. doi: 10.3390/antiox12081509. Antioxidants (Basel). 2023. PMID: 37627504 Free PMC article.
Here, we wanted to assess the valuable benefits of two less-studied OLE components-3,4-DHPEA-EDA (Oleacin, OC) and 3,4-DHPEA-EA (Oleuropein-Aglycone, OA)-directly purified from OLE using a cost-effective and environmentally sustainable method, in line with the princ …
Here, we wanted to assess the valuable benefits of two less-studied OLE components-3,4-DHPEA-EDA (Oleacin, OC) and 3,4-DHPEA-EA (Oleurope …
Oleuropein Aglycone: A Possible Drug against Degenerative Conditions. In Vivo Evidence of its Effectiveness against Alzheimer's Disease.
Casamenti F, Grossi C, Rigacci S, Pantano D, Luccarini I, Stefani M. Casamenti F, et al. J Alzheimers Dis. 2015;45(3):679-88. doi: 10.3233/JAD-142850. J Alzheimers Dis. 2015. PMID: 25649656 Review.
The present review summarizes the findings on the beneficial effects against neurodegeneration and other peripheral inflammatory and degenerative diseases of oleuropein aglycone (OLE), a natural phenol abundant in the extra virgin olive oil. ...
The present review summarizes the findings on the beneficial effects against neurodegeneration and other peripheral inflammatory and degener …
142 results