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79 results

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Page 1
Maclurin Exhibits Antioxidant and Anti-Tyrosinase Activities, Suppressing Melanogenesis.
Moon KM, Yang JH, Lee MK, Kwon EB, Baek J, Hwang T, Kim JI, Lee B. Moon KM, et al. Antioxidants (Basel). 2022 Jun 14;11(6):1164. doi: 10.3390/antiox11061164. Antioxidants (Basel). 2022. PMID: 35740060 Free PMC article.
Maclurin is rich in some edible fruits such as Morus alba (white mulberry) and Garcinia mangostana. ...Together, our study suggests that maclurin may be applied as an anti-melanogenic agent....
Maclurin is rich in some edible fruits such as Morus alba (white mulberry) and Garcinia mangostana. ...Together, our study suggests t
Maclurin exerts anti-cancer effects in human osteosarcoma cells via prooxidative activity and modulations of PARP, p38, and ERK signaling.
Lee YJ, Lee SY. Lee YJ, et al. IUBMB Life. 2021 Aug;73(8):1060-1072. doi: 10.1002/iub.2506. Epub 2021 May 28. IUBMB Life. 2021. PMID: 34003554 Free article.
Maclurin is known for its dual-sided effect on reactive oxygen species (ROS). ...Maclurin also inhibits the migration of U2OS human osteosarcoma cells. ...
Maclurin is known for its dual-sided effect on reactive oxygen species (ROS). ...Maclurin also inhibits the migration of U2OS
Maclurin Promotes the Chondrogenic Differentiation of Bone Marrow Mesenchymal Stem Cells by Regulating miR-203a-3p/Smad1.
Kong J, Zhou X, Lu J, Han Q, Ouyang X, Chen D, Liu A. Kong J, et al. Cell Reprogram. 2022 Feb;24(1):9-20. doi: 10.1089/cell.2021.0122. Cell Reprogram. 2022. PMID: 35180001
We obtained BMSCs from the bone marrow of Sprague Dawley rats. Cell Counting Kit-8 assays showed that maclurin (25 mug/mL) treatment was not toxic to BMSCs, and compared with untreated controls, maclurin upregulated Sox9 and Col2a expression. Quantitative-PCR reveal …
We obtained BMSCs from the bone marrow of Sprague Dawley rats. Cell Counting Kit-8 assays showed that maclurin (25 mug/mL) treatment …
Maclurin exerts anti-cancer effects on PC3 human prostate cancer cells via activation of p38 and inhibitions of JNK, FAK, AKT, and c-Myc signaling pathways.
Lee YJ, Jung O, Lee J, Son J, Cho JY, Ryou C, Lee SY. Lee YJ, et al. Nutr Res. 2018 Oct;58:62-71. doi: 10.1016/j.nutres.2018.07.003. Epub 2018 Jul 8. Nutr Res. 2018. PMID: 30340816
Maclurin is a phenolic compound extracted from purple mangosteen and mulberry twigs. ...In the apoptosis assay, maclurin significantly induced apoptosis of PC3 cells. Maclurin also showed significant anti-metastatic effects. ...
Maclurin is a phenolic compound extracted from purple mangosteen and mulberry twigs. ...In the apoptosis assay, maclurin signi
Maclurin inhibits caspase-11 non-canonical inflammasome in macrophages and ameliorates acute lethal sepsis in mice.
Joon Lee D, Yeol Lee S, Yi YS. Joon Lee D, et al. Int Immunopharmacol. 2024 Mar 10;129:111615. doi: 10.1016/j.intimp.2024.111615. Epub 2024 Feb 7. Int Immunopharmacol. 2024. PMID: 38330799
The regulatory role of maclurin, however, has never been demonstrated. This study investigated in vitro and in vivo anti-inflammatory roles of maclurin and the underlying mechanism in caspase-11 non-canonical inflammasome-stimulated inflammatory responses in macroph …
The regulatory role of maclurin, however, has never been demonstrated. This study investigated in vitro and in vivo anti-inflammatory …
Protective Effects of Maclurin against Benzo[a]pyrene via Aryl Hydrocarbon Receptor and Nuclear Factor Erythroid 2-Related Factor 2 Targeting.
Kim J, Park SH, Yang S, Oh SW, Kwon K, Park SJ, Yu E, Kim H, Park JY, Choi S, Yang S, Song M, Cho JY, Lee J. Kim J, et al. Antioxidants (Basel). 2021 Jul 26;10(8):1189. doi: 10.3390/antiox10081189. Antioxidants (Basel). 2021. PMID: 34439437 Free PMC article.
The B[a]P-induced dissociation of AHR from AHR-interacting protein (AIP) was suppressed by maclurin. Maclurin also inhibited the production of intracellular reactive oxygen species (ROS) induced by B[a]P. In addition, the antioxidant property of maclurin itse …
The B[a]P-induced dissociation of AHR from AHR-interacting protein (AIP) was suppressed by maclurin. Maclurin also inhibited t …
Maclurin protects against hydroxyl radical-induced damages to mesenchymal stem cells: antioxidant evaluation and mechanistic insight.
Li X, Gao Y, Li F, Liang A, Xu Z, Bai Y, Mai W, Han L, Chen D. Li X, et al. Chem Biol Interact. 2014 Aug 5;219:221-8. doi: 10.1016/j.cbi.2014.06.014. Epub 2014 Jun 25. Chem Biol Interact. 2014. PMID: 24973644
Maclurin, an exceptional member of phytophenol family, was found to effectively protect against mesenchymal stem cells (MSCs) oxidative damage induced by hydroxyl radical (OH) at 62.1-310.5 muM. ...Therefore, we concluded that: (i) maclurin can effectively protect a
Maclurin, an exceptional member of phytophenol family, was found to effectively protect against mesenchymal stem cells (MSCs) oxidati
Melanogenic Effects of Maclurin Are Mediated through the Activation of cAMP/PKA/CREB and p38 MAPK/CREB Signaling Pathways.
Hwang YS, Oh SW, Park SH, Lee J, Yoo JA, Kwon K, Park SJ, Kim J, Yu E, Cho JY, Lee J. Hwang YS, et al. Oxid Med Cell Longev. 2019 Dec 22;2019:9827519. doi: 10.1155/2019/9827519. eCollection 2019. Oxid Med Cell Longev. 2019. PMID: 31949887 Free PMC article.
Abnormal biology of melanocytes is closely associated with depigmented skin disorders such as vitiligo. In this study, we examined the effects of maclurin on melanogenesis and cytoprotection. Maclurin enhanced cellular tyrosinase activity as well as cellular melanin …
Abnormal biology of melanocytes is closely associated with depigmented skin disorders such as vitiligo. In this study, we examined the effec …
Maclurin suppresses migration and invasion of human non-small-cell lung cancer cells via anti-oxidative activity and inhibition of the Src/FAK-ERK-beta-catenin pathway.
Ku MJ, Kim JH, Lee J, Cho JY, Chun T, Lee SY. Ku MJ, et al. Mol Cell Biochem. 2015 Apr;402(1-2):243-52. doi: 10.1007/s11010-015-2331-4. Epub 2015 Jan 29. Mol Cell Biochem. 2015. PMID: 25630491
Maclurin suppresses intracellular ROS level in A549 human non-small-cell lung cancer cells. Also, maclurin down-regulates Src and ERK, which are well known to be regulated with redox state. ...
Maclurin suppresses intracellular ROS level in A549 human non-small-cell lung cancer cells. Also, maclurin down-regulates Src
79 results