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Year Number of Results
1990 1
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2,374 results

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Page 1
PML nuclear bodies.
Lallemand-Breitenbach V, de Thé H. Lallemand-Breitenbach V, et al. Cold Spring Harb Perspect Biol. 2010 May;2(5):a000661. doi: 10.1101/cshperspect.a000661. Epub 2010 Apr 21. Cold Spring Harb Perspect Biol. 2010. PMID: 20452955 Free PMC article. Review.
PML nuclear bodies are matrix-associated domains that recruit an astonishing variety of seemingly unrelated proteins. ...Functionally, PML bodies may sequester, modify or degrade partner proteins, but in many ways, PML bodies still constitute an enigma....
PML nuclear bodies are matrix-associated domains that recruit an astonishing variety of seemingly unrelated proteins. ...Functionally …
Promyelocytic leukemia protein (PML) and stem cells: from cancer to pluripotency.
Vogiatzoglou AP, Moretto F, Makkou M, Papamatheakis J, Kretsovali A. Vogiatzoglou AP, et al. Int J Dev Biol. 2022;66(1-2-3):85-95. doi: 10.1387/ijdb.210154av. Int J Dev Biol. 2022. PMID: 34881785 Free article. Review.
The promyelocytic leukemia protein (PML) is the core organizer of cognate nuclear bodies (PML-NBs). ...Although PML was originally recognized as a tumor-suppressive factor, more recent studies have revealed a "double-faced" agent role for PML. . …
The promyelocytic leukemia protein (PML) is the core organizer of cognate nuclear bodies (PML-NBs). ...Although PML was …
Chromosomal abnormalities and oncogenes.
Mitani K. Mitani K. Int J Hematol. 1996 Feb;63(2):81-93. doi: 10.1016/0925-5710(96)00440-9. Int J Hematol. 1996. PMID: 8867720 Review.
The alterations of transcription factor genes by chromosomal translocations play an important role in leukemogenesis and lymphomagenesis. ...These findings provide new insight into the molecular mechanism in leukemogenesis by the chimeric transcription fac …
The alterations of transcription factor genes by chromosomal translocations play an important role in leukemogenesis and lymph …
SOX2 downregulation of PML increases HCMV gene expression and growth of glioma cells.
Wen L, Wang XZ, Qiu Y, Zhou YP, Zhang QY, Cheng S, Sun JY, Jiang XJ, Rayner S, Britt WJ, Chen J, Hu F, Li FC, Luo MH, Cheng H. Wen L, et al. PLoS Pathog. 2023 Apr 14;19(4):e1011316. doi: 10.1371/journal.ppat.1011316. eCollection 2023 Apr. PLoS Pathog. 2023. PMID: 37058447 Free PMC article.
Our studies demonstrated that SOX2 downregulated promyelocytic leukemia (PML) and Sp100 and consequently facilitated viral gene expression by decreasing the amount of PML nuclear bodies in HCMV-infected glioma cells. ...These studies argue that HCMV gene expression …
Our studies demonstrated that SOX2 downregulated promyelocytic leukemia (PML) and Sp100 and consequently facilitated viral gene expre …
PML control of cytokine signaling.
Maarifi G, Chelbi-Alix MK, Nisole S. Maarifi G, et al. Cytokine Growth Factor Rev. 2014 Oct;25(5):551-61. doi: 10.1016/j.cytogfr.2014.04.008. Epub 2014 May 9. Cytokine Growth Factor Rev. 2014. PMID: 24861946 Review.
The involvement of PML in various cell processes, including cell death, senescence or antiviral defense underlines the multiple functions of PML due to its ability to interact with various partners either in the cytoplasm or in the nucleus. The importance of paracri …
The involvement of PML in various cell processes, including cell death, senescence or antiviral defense underlines the multiple funct …
Regulation of apoptosis by PML and the PML-NBs.
Bernardi R, Papa A, Pandolfi PP. Bernardi R, et al. Oncogene. 2008 Oct 20;27(48):6299-312. doi: 10.1038/onc.2008.305. Oncogene. 2008. PMID: 18931695 Review.
PML is essential for the proper assembly of a nuclear macromolecular structure called the PML nuclear body (PML-NB). PML and PML-NBs are functionally promiscuous and have been associated with the regulation of several cellular functions. ...
PML is essential for the proper assembly of a nuclear macromolecular structure called the PML nuclear body (PML-NB). …
PML links aberrant cytokine signaling and oncogenic stress to cellular senescence.
Bourdeau V, Baudry D, Ferbeyre G. Bourdeau V, et al. Front Biosci (Landmark Ed). 2009 Jan 1;14(2):475-85. doi: 10.2741/3256. Front Biosci (Landmark Ed). 2009. PMID: 19273079 Free article. Review.
The mechanism of PML-induction during senescence is complex and includes increased PML gene transcription by p53 or transcription factors of the interferon/Jak/Stat pathway. ...We think that the discovery of factors acting upstream or dow …
The mechanism of PML-induction during senescence is complex and includes increased PML gene transcription by p53 or …
Novel treatment of acute promyelocytic leukemia: As₂O₃, retinoic acid and retinoid pharmacology.
Zhu G. Zhu G. Curr Pharm Biotechnol. 2013;14(9):849-58. doi: 10.2174/1389201015666140113095812. Curr Pharm Biotechnol. 2013. PMID: 24433507 Review.
PML protein relocalizes into the wild-type nuclear body (PML-NB) configuration or/and wild-type RARa upregulated. ...Here, like v-erbA, PML/RARa is a (strong) transcriptional repressor of the RA receptor (RAR) complex, and PML/RARa fusion receptor gene …
PML protein relocalizes into the wild-type nuclear body (PML-NB) configuration or/and wild-type RARa upregulated. ...Here, lik …
Cytoplasmic PML: from molecular regulation to biological functions.
Jin G, Gao Y, Lin HK. Jin G, et al. J Cell Biochem. 2014 May;115(5):812-8. doi: 10.1002/jcb.24727. J Cell Biochem. 2014. PMID: 24288198 Review.
The tumor suppressor promyelocytic leukemia protein (PML) is predominantly localized in the nucleus, where it is essential for the formation and stabilization of the PML nuclear bodies (PML-NBs). PML-NBs are involved in the regulation of numerous cellu …
The tumor suppressor promyelocytic leukemia protein (PML) is predominantly localized in the nucleus, where it is essential for the fo …
PAX5 fusion genes in acute lymphoblastic leukemia: A literature review.
Fouad FM, Eid JI. Fouad FM, et al. Medicine (Baltimore). 2023 May 19;102(20):e33836. doi: 10.1097/MD.0000000000033836. Medicine (Baltimore). 2023. PMID: 37335685 Free PMC article. Review.
The interaction between PAX5 and FOXP1 negatively suppresses the Pax5 gene in B-ALL patients. Additionally, ELN and PML genes have been found to fuse with PAX5, leading to adverse effects on B-cell differentiation. ELN-PAX5 interaction results in the decreased expression o …
The interaction between PAX5 and FOXP1 negatively suppresses the Pax5 gene in B-ALL patients. Additionally, ELN and PML genes have be …
2,374 results