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1967 1
1968 1
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Page 1
Characterization of the antihistamines tripelennamine, methapyrilene, and thenyldiamine and their N-oxides by thermospray mass spectrometry.
Korfmacher WA, Freeman JP, Hansen EB Jr, Holder CL, Getek TA. Korfmacher WA, et al. J Anal Toxicol. 1989 Mar-Apr;13(2):94-6. doi: 10.1093/jat/13.2.94. J Anal Toxicol. 1989. PMID: 2567368
This study describes an investigation of the thermospray (TS) mass spectrometric analysis of tripelennamine, methapyrilene, thenyldiamine, and their N-oxide derivatives. These compounds were analyzed by direct injection TS mass spectrometry in the column bypass mode and wi …
This study describes an investigation of the thermospray (TS) mass spectrometric analysis of tripelennamine, methapyrilene, thenyldiamine …
Carcinogenicity of methapyrilene hydrochloride, mepyramine hydrochloride, thenyldiamine hydrochloride, and pyribenzamine hydrochloride in Sprague-Dawley rats.
Habs M, Shubik P, Eisenbrand G. Habs M, et al. J Cancer Res Clin Oncol. 1986;111(1):71-4. doi: 10.1007/BF00402780. J Cancer Res Clin Oncol. 1986. PMID: 3949852
Four histamine antagonists, methapyrilene, thenyldiamine, mepyramine and pyribenzamine were tested for carcinogenicity in rats by continuous application in drinking water. ...
Four histamine antagonists, methapyrilene, thenyldiamine, mepyramine and pyribenzamine were tested for carcinogenicity in rats by con …
Fungal transformations of antihistamines: metabolism of methapyrilene, thenyldiamine and tripelennamine to N-oxide and N-demethylated derivatives.
Cerniglia CE, Hansen EB Jr, Lambert KJ, Korfmacher WA, Miller DW. Cerniglia CE, et al. Xenobiotica. 1988 Mar;18(3):301-12. doi: 10.3109/00498258809041666. Xenobiotica. 1988. PMID: 2898181
Strains of the fungus Cunninghamella elegans ATCC 9245 and 36112 were tested for their ability to transform the antihistamines methapyrilene (I), thenyldiamine (II) and tripelennamine (III). 2. Antihistamine metabolites were isolated by h.p.l.c., and identified by their 1H …
Strains of the fungus Cunninghamella elegans ATCC 9245 and 36112 were tested for their ability to transform the antihistamines methapyrilene …
Trace determination of the antihistamines tripelennamine hydrochloride, thenyldiamine hydrochloride, and chlorothen citrate in admixture in animal feed, human urine, and wastewater by high-pressure liquid chromatography and use of a fluorescence detector.
Thompson HC Jr, Holder CL, Althaus JR. Thompson HC Jr, et al. Talanta. 1983 Apr;30(4):251-60. doi: 10.1016/0039-9140(83)80058-7. Talanta. 1983. PMID: 18963353
Tripelennamine hydrochloride, thenyldiamine hydrochloride, and chlorothen citrate have been used as antihistamines and for the treatment of asthma and bronchitis. ...Extraction efficiencies and data concerning the stability of tripelennamine hydrochloride and thenyldiam …
Tripelennamine hydrochloride, thenyldiamine hydrochloride, and chlorothen citrate have been used as antihistamines and for the treatm …
S-adenosylmethionine, S-adenosylhomocysteine and DNA methylation levels in the liver of rats fed methapyrilene and analogs.
Hernandez L, Allen PT, Poirier LA, Lijinsky W. Hernandez L, et al. Carcinogenesis. 1989 Mar;10(3):557-62. doi: 10.1093/carcin/10.3.557. Carcinogenesis. 1989. PMID: 2924400
The antihistamine methapyrilene (hydrochloride) and four close structural analogs, methaphenilene, methafurylene, thenyldiamine and clorothen, were given to rats at a concentration of 0.1% in drinking water for 34 weeks. ...
The antihistamine methapyrilene (hydrochloride) and four close structural analogs, methaphenilene, methafurylene, thenyldiamine and c …
A comparison of the actions of different bronchodilators in asthma.
Freedman BJ, Meisner P, Hill GB. Freedman BJ, et al. Thorax. 1968 Nov;23(6):590-7. doi: 10.1136/thx.23.6.590. Thorax. 1968. PMID: 4388005 Free PMC article.
These contained one or more of the following: isoprenaline, orciprenaline, isoetharine, phenylephrine, atropine methonitrate, and thenyldiamine. The dose was a single discharge from the container. The response was assessed by calculating the mean percentage change in F.E.V …
These contained one or more of the following: isoprenaline, orciprenaline, isoetharine, phenylephrine, atropine methonitrate, and thenyld …
Aggregation of antihistamines in aqueous solution: effect of counterions on self-association of pyridine derivatives.
Attwood D, Udeala OK. Attwood D, et al. J Pharm Sci. 1976 Jul;65(7):1053-7. doi: 10.1002/jps.2600650724. J Pharm Sci. 1976. PMID: 8628
The effects of electrolytes on the self-association of the antihistaminic drugs, tripelennamine hydrochloride, thenyldiamine hydrochloride, pyrilamine maleate, pheniramine maleate, chlorpheniramine maleate, and brompheniramine maleate, in aqueous solution were examined by …
The effects of electrolytes on the self-association of the antihistaminic drugs, tripelennamine hydrochloride, thenyldiamine hydrochl …
Mutagenicity of amine drugs and their products of nitrosation.
Andrews AW, Lijinsky W, Snyder SW. Andrews AW, et al. Mutat Res. 1984 Feb;135(2):105-8. doi: 10.1016/0165-1218(84)90162-9. Mutat Res. 1984. PMID: 6363913
Dimethyldodecylamine-N-oxide after nitrosation was mutagenic with S9 activation to TA1535 indicating a response to the nitrosomethyldodecylamine formed. Allantoin, pyrilamine, chlorothen, methafurylene and thenyldiamine were not mutagenic alone or after nitrosation....
Dimethyldodecylamine-N-oxide after nitrosation was mutagenic with S9 activation to TA1535 indicating a response to the nitrosomethyldodecyla …
Glutathione and lipid peroxide levels in rat liver following administration of methapyrilene and analogs.
Hernandez L, Lijinsky W. Hernandez L, et al. Chem Biol Interact. 1989;69(2-3):217-24. doi: 10.1016/0009-2797(89)90079-3. Chem Biol Interact. 1989. PMID: 2564814
Fischer 344 rats were given single-dose and multiple-dose treatments with the anti-histamine methapyrilene (MP), which is carcinogenic in rats, and with two non-carcinogenic analogs, methafurylene (MF) and thenyldiamine (TD) and the effects on malonaldehyde (MDA) formation …
Fischer 344 rats were given single-dose and multiple-dose treatments with the anti-histamine methapyrilene (MP), which is carcinogenic in ra …
15 results