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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1944 1
1945 27
1946 81
1947 108
1948 132
1949 79
1950 144
1951 155
1952 110
1953 111
1954 96
1955 116
1956 84
1957 103
1958 110
1959 82
1960 55
1961 82
1962 98
1963 212
1964 330
1965 221
1966 235
1967 281
1968 292
1969 372
1970 354
1971 354
1972 423
1973 421
1974 476
1975 424
1976 467
1977 614
1978 550
1979 612
1980 698
1981 621
1982 644
1983 612
1984 724
1985 752
1986 804
1987 690
1988 681
1989 683
1990 770
1991 778
1992 778
1993 766
1994 798
1995 802
1996 828
1997 819
1998 812
1999 887
2000 875
2001 844
2002 873
2003 990
2004 1079
2005 1264
2006 1349
2007 1447
2008 1519
2009 1762
2010 2202
2011 2551
2012 2879
2013 3080
2014 3126
2015 3297
2016 3236
2017 3232
2018 3098
2019 3074
2020 3311
2021 3151
2022 3093
2023 2512
2024 533

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70,597 results

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Page 1
Secosteroids of marine origin.
Sica D, Musumeci D. Sica D, et al. Steroids. 2004 Oct-Nov;69(11-12):743-56. doi: 10.1016/j.steroids.2004.09.001. Steroids. 2004. PMID: 15579326 Review.
This review describes the isolation from marine organisms of all secosteroids reported in the literature from 1972 to 2004. Secosteroids are highly oxidized metabolites with bond cleavage in the rings of the steroid tetracyclic nucleus. All secosteroids are g …
This review describes the isolation from marine organisms of all secosteroids reported in the literature from 1972 to 2004. Secost
Novel non-calcemic secosteroids that are produced by human epidermal keratinocytes protect against solar radiation.
Slominski AT, Janjetovic Z, Kim TK, Wasilewski P, Rosas S, Hanna S, Sayre RM, Dowdy JC, Li W, Tuckey RC. Slominski AT, et al. J Steroid Biochem Mol Biol. 2015 Apr;148:52-63. doi: 10.1016/j.jsbmb.2015.01.014. Epub 2015 Jan 21. J Steroid Biochem Mol Biol. 2015. PMID: 25617667 Free PMC article. Review.
The secosteroids attenuated ROS, H2O2 and NO production by UVB-irradiated keratinocytes and melanocytes, with an efficacy similar to 1,25(OH)2D3, while 25(OH)D3 had lower efficacy. ...In conclusion, novel secosteroids that can be produced by the action of CYP11A1 in …
The secosteroids attenuated ROS, H2O2 and NO production by UVB-irradiated keratinocytes and melanocytes, with an efficacy similar to …
Vitamin D and Vitamin D-Binding Protein in Health and Disease.
Delrue C, Speeckaert MM. Delrue C, et al. Int J Mol Sci. 2023 Feb 28;24(5):4642. doi: 10.3390/ijms24054642. Int J Mol Sci. 2023. PMID: 36902073 Free PMC article.
Vitamin D is a fat-soluble secosteroid that exists in two forms: vitamin D(2) and vitamin D(3) [...]....
Vitamin D is a fat-soluble secosteroid that exists in two forms: vitamin D(2) and vitamin D(3) [...]....
Nutrigenomics of Vitamin D.
Carlberg C. Carlberg C. Nutrients. 2019 Mar 21;11(3):676. doi: 10.3390/nu11030676. Nutrients. 2019. PMID: 30901909 Free PMC article. Review.
Vitamin D3 represents a master example of nutrigenomics, since via its metabolite 1alpha,25-dihydroxyvitamin D3, which binds with high-affinity to the vitamin D receptor, the secosteroid directly affects the epigenome and transcriptome at thousands of loci within the human …
Vitamin D3 represents a master example of nutrigenomics, since via its metabolite 1alpha,25-dihydroxyvitamin D3, which binds with high-affin …
Immunosuppressive 9,10-Secosteroids from the Gorgonian Verrucella umbraculum Collected in the South China Sea.
Li J, Sun YL, Tang H, Su L, Zheng GL, Zhang W. Li J, et al. J Nat Prod. 2021 May 28;84(5):1671-1675. doi: 10.1021/acs.jnatprod.1c00200. Epub 2021 May 9. J Nat Prod. 2021. PMID: 33966392
Four new 9,10-secosteroids, verrucellols A-D (1-4), together with 12 known derivatives (5-16) were isolated from the gorgonian Verrucella umbraculum collected in the South China Sea. ...These compounds exhibited significant suppressive effects on CD4(+) T lymphocyte cell d …
Four new 9,10-secosteroids, verrucellols A-D (1-4), together with 12 known derivatives (5-16) were isolated from the gorgonian Verruc …
Ubiquitin-Proteasome Modulating Dolabellanes and Secosteroids from Soft Coral Clavularia flava.
Chiu CY, Ling XH, Wang SK, Duh CY. Chiu CY, et al. Mar Drugs. 2020 Jan 3;18(1):39. doi: 10.3390/md18010039. Mar Drugs. 2020. PMID: 31947850 Free PMC article.
Chemical structure elucidation revealed they are dolabellane- and secosteroid-based compounds including a new dolabellane, clavinflol C (1), three known dolabellanes, stolonidiol (2), stolonidiol-17-acetate (3), and clavinflol B (4) as well as two new secosteroids, …
Chemical structure elucidation revealed they are dolabellane- and secosteroid-based compounds including a new dolabellane, clavinflol …
Secosteroids and norcembranoids from the soft coral Sinularia nanolobata.
Tseng YJ, Wang SK, Duh CY. Tseng YJ, et al. Mar Drugs. 2013 Aug 27;11(9):3288-96. doi: 10.3390/md11093288. Mar Drugs. 2013. PMID: 23985899 Free PMC article.
Two new 9,11-secosteroids, 22alpha-acetoxy-24-methylene-3beta,6alpha,11-trihydroxy-9, 11-seco-cholest-7-en-9-one (1) and 11-acetoxy-24-methylene-1beta,3beta,6alpha-trihydroxy-9, 11-seco-cholest-7-en-9-one (2), as well as two known norcembranoids, 5-epi-sinuleptolide (3) an …
Two new 9,11-secosteroids, 22alpha-acetoxy-24-methylene-3beta,6alpha,11-trihydroxy-9, 11-seco-cholest-7-en-9-one (1) and 11-acetoxy-2 …
Total Synthesis of Aplysiasecosterols A and B, Two Marine 9,11-Secosteroids.
Ohyoshi T, Iizumi H, Hosono S, Tano H, Kigoshi H. Ohyoshi T, et al. Org Lett. 2023 Jun 30;25(25):4725-4729. doi: 10.1021/acs.orglett.3c01692. Epub 2023 Jun 14. Org Lett. 2023. PMID: 37314938
This late-stage convergent synthesis, which has rarely been reported in secosteroid synthesis, can be adapted to many 9,11-secosteroids....
This late-stage convergent synthesis, which has rarely been reported in secosteroid synthesis, can be adapted to many 9,11-secoste
Calcifediol: Mechanisms of Action.
Donati S, Palmini G, Aurilia C, Falsetti I, Marini F, Giusti F, Iantomasi T, Brandi ML. Donati S, et al. Nutrients. 2023 Oct 17;15(20):4409. doi: 10.3390/nu15204409. Nutrients. 2023. PMID: 37892484 Free PMC article. Review.
Due to its essential role in calcium and phosphate homeostasis, the secosteroid hormone calcitriol has received growing attention over the last few years. ...
Due to its essential role in calcium and phosphate homeostasis, the secosteroid hormone calcitriol has received growing attention ove …
70,597 results
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