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1985 2
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291 results

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Page 1
The effect of sarafloxacin on Cu/ZnSOD structure and activity.
Cao Z, Liu R, Dong Z, Yang X, Chen Y. Cao Z, et al. Spectrochim Acta A Mol Biomol Spectrosc. 2015 Feb 5;136 Pt B:601-6. doi: 10.1016/j.saa.2014.09.073. Epub 2014 Oct 13. Spectrochim Acta A Mol Biomol Spectrosc. 2015. PMID: 25448960
The effect of sarafloxacin to Cu/ZnSOD was evaluated via investigating the change in Cu/ZnSOD structure and the structure basis activity upon sarafloxacin binding. Multi-spectroscopic methods, isothermal titration microcalorimetry (ITC) and molecular docking method …
The effect of sarafloxacin to Cu/ZnSOD was evaluated via investigating the change in Cu/ZnSOD structure and the structure basis activ …
Pharmacokinetic and pharmacodynamic modeling of sarafloxacin against avian pathogenic Escherichia coli in Muscovy ducks.
Yu Y, Zhou YF, Sun J, Shi W, Liao XP, Liu YH. Yu Y, et al. BMC Vet Res. 2017 Feb 10;13(1):47. doi: 10.1186/s12917-017-0964-0. BMC Vet Res. 2017. PMID: 28183350 Free PMC article.
CONCLUSIONS: Sarafloxacin administered at a 10 mg/kg dose may be insufficient for treatment of E. coli O78 infections with an MIC equally to or over 0.125 mug/ml. Furthermore, higher doses of sarafloxacin are required to minimize antimicrobial resistance considering …
CONCLUSIONS: Sarafloxacin administered at a 10 mg/kg dose may be insufficient for treatment of E. coli O78 infections with an MIC equ …
Rapid and Simple Determination of Sarafloxacin and Difloxacin in Beef by Capillary Electrophoresis Coupled with Solid-Phase Extraction.
Wang Q, Zhao R, Cui Y, Liu C, Liang L, Yan S. Wang Q, et al. J Anal Methods Chem. 2018 Feb 20;2018:1981436. doi: 10.1155/2018/1981436. eCollection 2018. J Anal Methods Chem. 2018. PMID: 29675283 Free PMC article.
The linear range of the method was 1-20 mug/mL with LOD 0.8 mug/mL for sarafloxacin and 0.5-20 mug/mL with LOD 0.3 mug/mL for difloxacin. The RSDs for the peak area of 8 mug/mL sarafloxacin were 4.8% (intraday) and 7.8% (interday), respectively. The proposed method …
The linear range of the method was 1-20 mug/mL with LOD 0.8 mug/mL for sarafloxacin and 0.5-20 mug/mL with LOD 0.3 mug/mL for difloxa …
Pharmacokinetics of sarafloxacin in allogynogenetic silver crucian carp, Carassius auratus gibelio.
Fang X, Zhou J, Liu X. Fang X, et al. Fish Physiol Biochem. 2016 Feb;42(1):335-41. doi: 10.1007/s10695-015-0141-y. Epub 2015 Nov 12. Fish Physiol Biochem. 2016. PMID: 26563280
The plasma concentrations of sarafloxacin were determined by high-performance liquid chromatography. ...The volume of distribution, V(d(area)), was estimated to be 5.95 L/kg, indicating good tissue penetration of sarafloxacin in the fish. Area under the concentratio …
The plasma concentrations of sarafloxacin were determined by high-performance liquid chromatography. ...The volume of distribution, V …
Effects of sarafloxacin hydrochloride on human enteric bacteria under simulated human gut conditions.
McConville ML, Dijkstra JW, Stamm JM, van Saene JJ, Nouws JF. McConville ML, et al. Vet Q. 1995 Mar;17(1):1-5. doi: 10.1080/01652176.1995.9694519. Vet Q. 1995. PMID: 7610549
The survival of bacteria in the simulation model and any subsequent change in the sensitivity of isolates to sarafloxacin were measured. The inhibitory level of sarafloxacin for the tested bacteria was strain dependent. It appeared that in broth culture Escherichia …
The survival of bacteria in the simulation model and any subsequent change in the sensitivity of isolates to sarafloxacin were measur …
L-leucine increases the sensitivity of drug-resistant Salmonella to sarafloxacin by stimulating central carbon metabolism and increasing intracellular reactive oxygen species level.
Yang H, Zhou Y, Luo Q, Zhu C, Fang B. Yang H, et al. Front Microbiol. 2023 May 12;14:1186841. doi: 10.3389/fmicb.2023.1186841. eCollection 2023. Front Microbiol. 2023. PMID: 37250042 Free PMC article.
METHODS: CICC21484 were passaged in medium with and without sarafloxacin and obtain sarafloxacin- susceptible Salmonella Typhimurium (SAR-S) and sarafloxacin resistant Salmonella Typhimurium (SAR-R), respectively. ...RESULTS: We confirmed that exogenous L-leu …
METHODS: CICC21484 were passaged in medium with and without sarafloxacin and obtain sarafloxacin- susceptible Salmonella Typhi …
Potential toxicity of sarafloxacin to catalase: spectroscopic, ITC and molecular docking descriptions.
Cao Z, Liu R, Yang B. Cao Z, et al. Spectrochim Acta A Mol Biomol Spectrosc. 2013 Nov;115:457-63. doi: 10.1016/j.saa.2013.06.093. Epub 2013 Jul 2. Spectrochim Acta A Mol Biomol Spectrosc. 2013. PMID: 23871971
The interaction between sarafloxacin and catalase (CAT) was studied by fluorescence spectroscopy, UV-visible absorption spectroscopy, circular dichroism (CD) spectroscopy, isothermal titration microcalorimetry (ITC) and molecular docking method. After deducting the inner f …
The interaction between sarafloxacin and catalase (CAT) was studied by fluorescence spectroscopy, UV-visible absorption spectroscopy, …
Antibiotic discovery against Piscirickettsia salmonis using a combined in silico and in vitro approach.
Beltrán JF, Yáñez A, Herrera-Belén L, Contreras FP, Blanco JA, Flores-Martin SN, Zamorano M, Farias JG. Beltrán JF, et al. Microb Pathog. 2023 Jul;180:106122. doi: 10.1016/j.micpath.2023.106122. Epub 2023 Apr 22. Microb Pathog. 2023. PMID: 37094756
The in silico results of this work showed that flumequine (-6.6 kcal/mol), finafloxacin (-7.2 kcal/mol), rosoxacin (-6.6 kcal/mol), elvitegravir (-6.4 kcal/mol), sarafloxacin (-8.3 kcal/mol), orbifloxacin (-7.9 kcal/mol), and sparfloxacin (-7.2 kcal/mol) are docked with go …
The in silico results of this work showed that flumequine (-6.6 kcal/mol), finafloxacin (-7.2 kcal/mol), rosoxacin (-6.6 kcal/mol), elvitegr …
Simultaneous determination of chlortetracycline, ampicillin and sarafloxacin in milk using capillary electrophoresis with electrochemiluminescence detection.
Long C, Deng B, Sun S, Meng S. Long C, et al. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2017 Jan;34(1):24-31. doi: 10.1080/19440049.2016.1254820. Epub 2016 Nov 17. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2017. PMID: 27805474
The correlation coefficients of chlortetracycline, ampicilline and sarafloxacin were determined as 0.9997, 0.9952 and 0.9978, respectively. Detection limits (S/N = 3) of chlortetracycline, ampicilline and sarafloxacin were found as 0.017, 0.018 and 0.0013 mug ml(-1) …
The correlation coefficients of chlortetracycline, ampicilline and sarafloxacin were determined as 0.9997, 0.9952 and 0.9978, respect …
Pharmacokinetics of sarafloxacin in pigs and broilers following intravenous, intramuscular, and oral single-dose applications.
Ding HZ, Zeng ZL, Fung KF, Chen ZL, Qiao GL. Ding HZ, et al. J Vet Pharmacol Ther. 2001 Oct;24(5):303-8. doi: 10.1046/j.1365-2885.2001.00348.x. J Vet Pharmacol Ther. 2001. PMID: 11696079
Pharmacokinetics of sarafloxacin, a fluoroquinolone antibiotic, was determined in pigs and broilers after intravenous (i.v.), intramuscular (i.m.), or oral (p.o.) administration at a single dose of 5 (pigs) or 10 mg/kg (broilers). ...Areas under the curve (AUC), mean resid …
Pharmacokinetics of sarafloxacin, a fluoroquinolone antibiotic, was determined in pigs and broilers after intravenous (i.v.), intramu …
291 results