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1980 2
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New antitumor imidazole derivative, 5-carbamoyl-1H-imidazol-4-yl piperonylate, as an inhibitor of purine synthesis and its activation by adenine phosphoribosyltransferase.
Fukui M, Inaba M, Tsukagoshi S, Sakurai Y. Fukui M, et al. Cancer Res. 1982 Mar;42(3):1098-102. Cancer Res. 1982. PMID: 6120758
The mechanism of action of 5-carbamoyl-1H-imidazol-4-yl piperonylate (SL-1250), which has a broad antitumor spectrum, was examined by in vitro cell culture and enzymatic studies. ...Thus, SL-1250 might b …
The mechanism of action of 5-carbamoyl-1H-imidazol-4-yl piperonylate (SL-1250 …
Collateral sensitivity of 6-mercaptopurine-resistant sublines of P388 and L1210 leukemia to the new purine antagonists, 5-carbamoyl-1H-imidazol-4-yl piperonylate and 4-carbamoylimidazolium 5-olate.
Inaba M, Fukui M, Yoshida N, Tsukagoshi S, Sakurai Y. Inaba M, et al. Cancer Res. 1982 Mar;42(3):1103-6. Cancer Res. 1982. PMID: 6277474
Two new purine antagonists, 5-carbamoyl-1H-imidazol-4-yl piperonylate (SL-1250) and 4-carbamoylimidazolium 5-olate (SM-108), were investigated for their antitumor activities against 6-mercaptopurine (6-MP)-resistant s …
Two new purine antagonists, 5-carbamoyl-1H-imidazol-4-yl piperonylate (SL-1250 …
Antitumor activities of newly synthesized 5-carbamoyl-1 H-imidazol-4yl 1-adamantanecarboxylate and 5-carbamoyl-1H-imidazol-4yl piperonylate.
Yoshida N, Kiyohara T, Fukui M, Atsumi T, Ogino S, Inaba M, Tsukagoshi S, Sakurai Y. Yoshida N, et al. Cancer Res. 1980 Oct;40(10):3810-4. Cancer Res. 1980. PMID: 7438064
In synthetic studies on the chemical modification of the nucleoside antibiotic bredinin, two new derivatives, 5-carbamoyl-1H-imidazol-4-yl 1-adamantanecarboxylate and 5-carbamoyl-1H-imidazol-4-yl piperonylate, were found to possess …
In synthetic studies on the chemical modification of the nucleoside antibiotic bredinin, two new derivatives, 5-carbamoyl-1H-imidazol-4-yl 1 …