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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1953 1
1959 2
1960 1
1962 1
1963 1
1965 2
1969 2
1970 2
1971 2
1972 1
1973 1
1974 1
1975 1
1976 2
1977 2
1978 2
1979 4
1980 6
1981 1
1982 3
1983 7
1984 3
1985 8
1986 9
1987 6
1988 12
1989 8
1990 14
1991 11
1992 6
1993 9
1994 21
1995 19
1996 18
1997 21
1998 31
1999 39
2000 50
2001 38
2002 49
2003 66
2004 79
2005 82
2006 93
2007 106
2008 116
2009 95
2010 139
2011 142
2012 164
2013 179
2014 187
2015 172
2016 196
2017 222
2018 248
2019 246
2020 338
2021 374
2022 496
2023 454
2024 196

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4,299 results

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Page 1
Naringenin attenuates non-alcoholic fatty liver disease by down-regulating the NLRP3/NF-kappaB pathway in mice.
Wang Q, Ou Y, Hu G, Wen C, Yue S, Chen C, Xu L, Xie J, Dai H, Xiao H, Zhang Y, Qi R. Wang Q, et al. Br J Pharmacol. 2020 Apr;177(8):1806-1821. doi: 10.1111/bph.14938. Epub 2020 Jan 30. Br J Pharmacol. 2020. PMID: 31758699 Free PMC article.
Treating the HepG2 cells with naringenin or NLRP3 inhibitor MCC950 reduced lipid accumulation. Naringenin inhibited activation of the NLRP3/NF-kappaB pathway stimulated by OA together with LPS. In KCs isolated from WT mice, naringenin inhibited NLRP3 expressi …
Treating the HepG2 cells with naringenin or NLRP3 inhibitor MCC950 reduced lipid accumulation. Naringenin inhibited activation …
Naringenin: A potential flavonoid phytochemical for cancer therapy.
Motallebi M, Bhia M, Rajani HF, Bhia I, Tabarraei H, Mohammadkhani N, Pereira-Silva M, Kasaii MS, Nouri-Majd S, Mueller AL, Veiga FJB, Paiva-Santos AC, Shakibaei M. Motallebi M, et al. Life Sci. 2022 Sep 15;305:120752. doi: 10.1016/j.lfs.2022.120752. Epub 2022 Jun 29. Life Sci. 2022. PMID: 35779626 Review.
Collected data from in vitro and in vivo studies show the inactivation of carcinogens after treatment with pure naringenin, naringenin-loaded nanoparticles, and also naringenin in combination with anti-cancer agents in various malignancies, such as colon canc …
Collected data from in vitro and in vivo studies show the inactivation of carcinogens after treatment with pure naringenin, naring …
Naringenin alleviates nonalcoholic steatohepatitis in middle-aged Apoe(-/-)mice: role of SIRT1.
Hua YQ, Zeng Y, Xu J, Xu XL. Hua YQ, et al. Phytomedicine. 2021 Jan;81:153412. doi: 10.1016/j.phymed.2020.153412. Epub 2020 Nov 18. Phytomedicine. 2021. PMID: 33234364
BACKGROUND: Naringenin is naturally isolated from citrus fruits possessing many pharmacological activities. However, little is known about the effect of naringenin on nonalcoholic steatohepatitis (NASH) in the model of metabolic syndrome. ...
BACKGROUND: Naringenin is naturally isolated from citrus fruits possessing many pharmacological activities. However, little is known …
Naringenin as a potential immunomodulator in therapeutics.
Zeng W, Jin L, Zhang F, Zhang C, Liang W. Zeng W, et al. Pharmacol Res. 2018 Sep;135:122-126. doi: 10.1016/j.phrs.2018.08.002. Epub 2018 Aug 3. Pharmacol Res. 2018. PMID: 30081177 Review.
The mechanism of action of naringenin is not completely understood but recent mechanistic studies revealed that naringenin suppresses inflammatory cytokine production through both transcriptional and post-transcriptional mechanisms. ...Therefore, naringenin m …
The mechanism of action of naringenin is not completely understood but recent mechanistic studies revealed that naringenin sup …
A Scoping Review of the Skeletal Effects of Naringenin.
Nor Muhamad ML, Ekeuku SO, Wong SK, Chin KY. Nor Muhamad ML, et al. Nutrients. 2022 Nov 16;14(22):4851. doi: 10.3390/nu14224851. Nutrients. 2022. PMID: 36432535 Free PMC article. Review.
Various natural compounds can positively influence the skeletal remodelling process, of which naringenin is a candidate. Naringenin is an anti-inflammatory and antioxidant compound found in citrus fruits and grapefruit. ...Naringenin also inhibited osteoclast …
Various natural compounds can positively influence the skeletal remodelling process, of which naringenin is a candidate. Naringeni …
Network pharmacology and bioinformatics analysis identifies potential therapeutic targets of Naringenin against COVID-19/LUSC.
Wu WY, Jiao X, Song WX, Wu P, Xiao PQ, Huang XF, Wang K, Zhan SF. Wu WY, et al. Front Endocrinol (Lausanne). 2023 Jun 6;14:1187882. doi: 10.3389/fendo.2023.1187882. eCollection 2023. Front Endocrinol (Lausanne). 2023. PMID: 37347115 Free PMC article.
Patients with LUSC could be at risk for COVID-19, We conducted this study to examine the potential for naringenin to develop into an ideal medicine and investigate the underlying action mechanisms of naringenin in COVID-19 and LUSC due to the anti-viral, anti-tumor, …
Patients with LUSC could be at risk for COVID-19, We conducted this study to examine the potential for naringenin to develop into an …
Naringenin ameliorates collagen-induced arthritis through activating AMPK-mediated autophagy in macrophages.
Zhang W, Zhang Y, Zhang J, Deng C, Zhang C. Zhang W, et al. Immun Inflamm Dis. 2023 Oct;11(10):e983. doi: 10.1002/iid3.983. Immun Inflamm Dis. 2023. PMID: 37904715 Free PMC article.
The study also involved lipopolysaccharides (LPS)-induced RAW264.7 cells to further evaluate the effects of Naringenin. Mechanistic studies were conducted to elucidate the signaling pathways involved in Naringenin's actions. ...Further exploration revealed that N …
The study also involved lipopolysaccharides (LPS)-induced RAW264.7 cells to further evaluate the effects of Naringenin. Mechanistic s …
Naringenin enhances anti-proliferation effect of 1-ferrocenyl-3-(4-methylsulfonylphenyl) propen-1-one on two different cells via targeting calmodulin signaling pathway.
Rajabi S, Noori S, Ashrafi MR, Movahed MA, Farzaneh S, Zarghi A. Rajabi S, et al. Mol Biol Rep. 2022 Feb;49(2):1027-1036. doi: 10.1007/s11033-021-06923-8. Epub 2022 Jan 14. Mol Biol Rep. 2022. PMID: 35028851
RESULTS: The combination of FMSP and naringenin had more inhibitory effects on CaM structure than FMSP and naringenin alone. ...FMSP and naringenin synergistically increased Km values at a higher level compared to FMSP or naringenin alone. ...
RESULTS: The combination of FMSP and naringenin had more inhibitory effects on CaM structure than FMSP and naringenin alone. . …
Pharmacokinetic, pharmacodynamic and formulations aspects of Naringenin: An update.
Joshi R, Kulkarni YA, Wairkar S. Joshi R, et al. Life Sci. 2018 Dec 15;215:43-56. doi: 10.1016/j.lfs.2018.10.066. Epub 2018 Nov 1. Life Sci. 2018. PMID: 30391464 Review.
Furthermore, the review also focuses on molecular level mechanisms of Naringenin for its therapeutic effect. Various attempts have been made to formulate advanced dosage forms to address issue of solubility of Naringenin. Systematic review of data published on formu …
Furthermore, the review also focuses on molecular level mechanisms of Naringenin for its therapeutic effect. Various attempts have be …
Naringenin and naringin in cardiovascular disease prevention: A preclinical review.
Heidary Moghaddam R, Samimi Z, Moradi SZ, Little PJ, Xu S, Farzaei MH. Heidary Moghaddam R, et al. Eur J Pharmacol. 2020 Nov 15;887:173535. doi: 10.1016/j.ejphar.2020.173535. Epub 2020 Sep 8. Eur J Pharmacol. 2020. PMID: 32910944 Review.
In this review, based on the latest evidence, we present a summary of the impact of naringin, and naringenin on cardiovascular disease, and analyze and discuss the basic roles of naringin and naringenin and their mechanisms of actions in cardiovascular disease and o …
In this review, based on the latest evidence, we present a summary of the impact of naringin, and naringenin on cardiovascular diseas …
4,299 results