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Metabolism and transport of oxazaphosphorines and the clinical implications.
Zhang J, Tian Q, Yung Chan S, Chuen Li S, Zhou S, Duan W, Zhu YZ. Zhang J, et al. Drug Metab Rev. 2005;37(4):611-703. doi: 10.1080/03602530500364023. Drug Metab Rev. 2005. PMID: 16393888 Review.
These derivatives include mafosfamide (NSC 345842), glufosfamide (D19575, beta-D-glucosylisophosphoramide mustard), NSC 612567 (aldophosphamide perhydrothiazine), and NSC 613060 (aldophosphamide thiazolidine). ...However, those newly synthesized oxazaphosphorine der …
These derivatives include mafosfamide (NSC 345842), glufosfamide (D19575, beta-D-glucosylisophosphoramide mustard), NSC 612567 …
Design of new oxazaphosphorine anticancer drugs.
Liang J, Huang M, Duan W, Yu XQ, Zhou S. Liang J, et al. Curr Pharm Des. 2007;13(9):963-78. doi: 10.2174/138161207780414296. Curr Pharm Des. 2007. PMID: 17430192 Review.
These include mafosfamide (NSC 345842), glufosfamide (D19575, beta-D-glucosylisophosphoramide mustard), S-(-)-bromofosfamide (CBM-11), NSC 612567 (aldophosphamide perhydrothiazine) and NSC 613060 (aldophosphamide thiazolidine). ...
These include mafosfamide (NSC 345842), glufosfamide (D19575, beta-D-glucosylisophosphoramide mustard), S-(-)-bromofosfamide (CBM-11), NS …
Thiazolidinyl- and perhydrothiazinylphosphamidesters: toxicity and preliminary antitumour evaluation.
Voelcker G, Bielicki L, Hohorst HJ. Voelcker G, et al. J Cancer Res Clin Oncol. 1997;123(11-12):623-31. doi: 10.1007/s004320050116. J Cancer Res Clin Oncol. 1997. PMID: 9620221
This goal is facilitated by the rapid transfer of 4-OH-CP released from the perhyrothiazine derivative NSC 612567 to protein SH groups, as shown by protein-binding studies. ...The acute toxicity determined in mice was 2400 mg/kg for NSC 613060 and 1900 mg/kg for …
This goal is facilitated by the rapid transfer of 4-OH-CP released from the perhyrothiazine derivative NSC 612567 to protein S …