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1990 1
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Page 1
[Pharmacological properties of (+/-)-4-[2-hydroxy-3-(3-(2-methoxyphenoxy)-2-propylamino)propoxy]-1(2H) -isoquinolinone (N-1518), a new combined alpha- and beta-adrenoceptor blocking drug].
Sugai T. Sugai T. Nihon Yakurigaku Zasshi. 1990 Sep;96(3):117-27. doi: 10.1254/fpj.96.3_117. Nihon Yakurigaku Zasshi. 1990. PMID: 1980255 Japanese.
As judged by pA2 values and DR10 values, N-1518 was as potent as labetalol in blocking alpha- and beta-adrenoceptors. ...N-1518 has no intrinsic sympathomimetic activity in reserpinized rats and has no local anesthetic activity in guinea pigs. ...
As judged by pA2 values and DR10 values, N-1518 was as potent as labetalol in blocking alpha- and beta-adrenoceptors. ...N …
Impact of Diabetes Mellitus on Adverse Outcomes After Meningioma Surgery.
Randhawa KS, Choi CB, Shah AD, Parray A, Fang CH, Liu JK, Baredes S, Eloy JA. Randhawa KS, et al. World Neurosurg. 2021 Aug;152:e429-e435. doi: 10.1016/j.wneu.2021.05.101. Epub 2021 May 29. World Neurosurg. 2021. PMID: 34062298
RESULTS: After selecting for patients with primary diagnosis of meningioma who underwent a resection procedure, 7745 individuals were identified and divided into diabetic (n = 1518) and nondiabetic (n = 6227) cohorts. Demographics, hospital characteristics, and como …
RESULTS: After selecting for patients with primary diagnosis of meningioma who underwent a resection procedure, 7745 individuals were identi …
Theory of mind in schizophrenia: meta-analysis.
Sprong M, Schothorst P, Vos E, Hox J, van Engeland H. Sprong M, et al. Br J Psychiatry. 2007 Jul;191:5-13. doi: 10.1192/bjp.bp.107.035899. Br J Psychiatry. 2007. PMID: 17602119 Review.
METHOD: Twenty-nine studies of mentalising in schizophrenia (combined n=1518), published between January 1993 and May 2006, were included to estimate overall effect size. ...
METHOD: Twenty-nine studies of mentalising in schizophrenia (combined n=1518), published between January 1993 and May 2006, we …
Plasma protein N-glycosylation is associated with cardiovascular disease, nephropathy, and retinopathy in type 2 diabetes.
Memarian E, 't Hart LM, Slieker RC, Lemmers RFL, van der Heijden AA, Rutters F, Nijpels G, Schoep E, Lieverse AG, Sijbrands EJG, Wuhrer M, van Hoek M, Dotz V. Memarian E, et al. BMJ Open Diabetes Res Care. 2021 Oct;9(1):e002345. doi: 10.1136/bmjdrc-2021-002345. BMJ Open Diabetes Res Care. 2021. PMID: 34645615 Free PMC article.
Here, we assessed TPNG in relation to type 2 diabetes complications in subsamples of two Dutch cohorts using mass spectrometry (n=1815 in DiaGene and n=1518 in Hoorn Diabetes Care System). RESEARCH DESIGN AND METHODS: Blood plasma samples and technical replicates we …
Here, we assessed TPNG in relation to type 2 diabetes complications in subsamples of two Dutch cohorts using mass spectrometry (n=1815 in Di …
Factors Associated With the Intention to Receive the COVID-19 Vaccine: Cross-sectional National Study.
Kasting ML, Macy JT, Grannis SJ, Wiensch AJ, Lavista Ferres JM, Dixon BE. Kasting ML, et al. JMIR Public Health Surveill. 2022 Nov 14;8(11):e37203. doi: 10.2196/37203. JMIR Public Health Surveill. 2022. PMID: 36219842 Free PMC article.
RESULTS: The majority of participants were male (n=974, 59.3%), White (n=1347, 82.0%), and non-Hispanic (n=1518, 92.4%) and reported they had already received a COVID-19 vaccine or definitely would when it was available to them (n=1306, 79.5%). ...
RESULTS: The majority of participants were male (n=974, 59.3%), White (n=1347, 82.0%), and non-Hispanic (n=1518, 92.4%) and re …
Discussions between health professionals and smokers about nicotine vaping products: results from the 2016 ITC Four Country Smoking and Vaping Survey.
Gravely S, Thrasher JF, Cummings KM, Ouimet J, McNeill A, Meng G, Lindblom EN, Loewen R, O'Connor RJ, Thompson ME, Hitchman SC, Hammond D, Heckman BW, Borland R, Yong HH, Elton-Marshall T, Bansal-Travers M, Gartner C, Fong GT. Gravely S, et al. Addiction. 2019 Oct;114 Suppl 1(Suppl 1):71-85. doi: 10.1111/add.14527. Epub 2019 Mar 7. Addiction. 2019. PMID: 30548374 Free PMC article.
PARTICIPANTS: A total of 6615 adult smokers who reported having visited an HP in the last year (drawn from the total sample of 12 294 4CV1 respondents, of whom 9398 reported smoking cigarettes daily or weekly). Respondents were from the United States (n = 1518), Eng …
PARTICIPANTS: A total of 6615 adult smokers who reported having visited an HP in the last year (drawn from the total sample of 12 294 4CV1 r …
Mortality in youth-onset type 1 and type 2 diabetes: The SEARCH for Diabetes in Youth study.
Reynolds K, Saydah SH, Isom S, Divers J, Lawrence JM, Dabelea D, Mayer-Davis EJ, Imperatore G, Bell RA, Hamman RF. Reynolds K, et al. J Diabetes Complications. 2018 Jun;32(6):545-549. doi: 10.1016/j.jdiacomp.2018.03.015. Epub 2018 Apr 4. J Diabetes Complications. 2018. PMID: 29685480 Free PMC article.
METHODS: We included 8358 individuals newly-diagnosed with type 1 (n = 6840) or type 2 (n = 1518) diabetes from 1/1/2002-12/31/2008. We searched the National Death Index through 12/31/2010. ...
METHODS: We included 8358 individuals newly-diagnosed with type 1 (n = 6840) or type 2 (n = 1518) diabetes from 1/1/2002-12/31 …
Long-term outcome of fusion for degenerative disc disease in the lumbar spine.
Endler P, Ekman P, Berglund I, Möller H, Gerdhem P. Endler P, et al. Bone Joint J. 2019 Dec;101-B(12):1526-1533. doi: 10.1302/0301-620X.101B12.BJJ-2019-0427.R1. Bone Joint J. 2019. PMID: 31786998
Patient-reported outcome data were available preoperatively (n = 2874) and at one year (n = 2274), two years (n = 1958), and a mean of 6.9 years (n = 1518) postoperatively and consisted of global assessment and visual analogue scales of leg and back pain, Oswestry D …
Patient-reported outcome data were available preoperatively (n = 2874) and at one year (n = 2274), two years (n = 1958), and a mean of 6.9 y …
Metformin and statin use associate with plasma protein N-glycosylation in people with type 2 diabetes.
Singh SS, Naber A, Dotz V, Schoep E, Memarian E, Slieker RC, Elders PJM, Vreeker G, Nicolardi S, Wuhrer M, Sijbrands EJG, Lieverse AG, 't Hart LM, van Hoek M. Singh SS, et al. BMJ Open Diabetes Res Care. 2020 Jul;8(1):e001230. doi: 10.1136/bmjdrc-2020-001230. BMJ Open Diabetes Res Care. 2020. PMID: 32616483 Free PMC article.
RESEARCH DESIGN AND METHODS: After enzymatic release from glycoproteins, N-glycans were measured by matrix-assisted laser desorption/ionization mass spectrometry in the DiaGene (n=1815) and Hoorn Diabetes Care System (n=1518) cohorts. Multiple linear regression was …
RESEARCH DESIGN AND METHODS: After enzymatic release from glycoproteins, N-glycans were measured by matrix-assisted laser desorption/ionizat …
Real-world outcomes in metastatic HR+/HER2-, HER2+ and triple negative breast cancer after start of first-line therapy.
W DeClue R, Fisher MD, Gooden K, Walker MS, Le TK. W DeClue R, et al. Future Oncol. 2023 Apr;19(13):909-923. doi: 10.2217/fon-2022-0894. Epub 2023 May 16. Future Oncol. 2023. PMID: 37191097 Free article.
Aim: We evaluated outcomes of first-line (1L) treatment of metastatic breast cancer by biomarker subtype in the community setting over the last decade. Methods: Eligible patients (n = 1518) were female, 18 years, diagnosed with metastatic breast cancer 2010 or later …
Aim: We evaluated outcomes of first-line (1L) treatment of metastatic breast cancer by biomarker subtype in the community setting over the l …
51 results