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Antioxidant, Anti-Inflammatory, Anti-Menopausal, and Anti-Cancer Effects of Lignans and Their Metabolites.
Jang WY, Kim MY, Cho JY. Jang WY, et al. Int J Mol Sci. 2022 Dec 7;23(24):15482. doi: 10.3390/ijms232415482. Int J Mol Sci. 2022. PMID: 36555124 Free PMC article. Review.
Among many therapeutic candidates, lignans, absorbed from various plant sources, represent a type of phytoestrogen classified into secoisolariciresionol (Seco), pinoresinol (Pino), matairesinol (Mat), medioresinol (Med), sesamin (Ses), syringaresinol (Syr), and lariciresin …
Among many therapeutic candidates, lignans, absorbed from various plant sources, represent a type of phytoestrogen classified into secoisola …
[Phytoestrogens].
Zittermann A. Zittermann A. Zentralbl Gynakol. 2003 Jun;125(6):195-201. doi: 10.1055/s-2003-42601. Zentralbl Gynakol. 2003. PMID: 14556117 Review. German.
The soy-isoflavones genistein and daidzein and the flaxseed-lignans secoisolariciresinol and matairesinol belong to the group of phytoestrogens. Epidemiological data suggest that phytoestrogens have a preventive effect against various estrogen-related diseases/symptoms suc …
The soy-isoflavones genistein and daidzein and the flaxseed-lignans secoisolariciresinol and matairesinol belong to the group of phyt …
Anti-osteoclastogenic activity of matairesinol via suppression of p38/ERK-NFATc1 signaling axis.
Choi SW, Park KI, Yeon JT, Ryu BJ, Kim KJ, Kim SH. Choi SW, et al. BMC Complement Altern Med. 2014 Jan 21;14:35. doi: 10.1186/1472-6882-14-35. BMC Complement Altern Med. 2014. PMID: 24444335 Free PMC article.
BACKGROUND: Matairesinol is a plant lignan present in a wide variety of foodstuffs such as seeds, vegetables and fruits. ...Ectopic overexpression of NFATc1 blunted the anti-osteoclastogenic effect of matairesinol implicating NFATc1 in the action of matairesinol …
BACKGROUND: Matairesinol is a plant lignan present in a wide variety of foodstuffs such as seeds, vegetables and fruits. ...Ectopic o …
Matairesinol Nanoparticles Restore Chemosensitivity and Suppress Colorectal Cancer Progression in Preclinical Models: Role of Lipid Metabolism Reprogramming.
Wu S, Wang J, Fu Z, Familiari G, Relucenti M, Aschner M, Li X, Chen H, Chen R. Wu S, et al. Nano Lett. 2023 Mar 8;23(5):1970-1980. doi: 10.1021/acs.nanolett.3c00035. Epub 2023 Feb 20. Nano Lett. 2023. PMID: 36802650
Herein, the metabolic profiles in the plasma between CRC patients and paired healthy controls were compared using metabolomics assays. Matairesinol downregulation was evident in CRC patients, and matairesinol supplementation significantly represses CRC tumorigenesis …
Herein, the metabolic profiles in the plasma between CRC patients and paired healthy controls were compared using metabolomics assays. Ma …
Bioavailability of phyto-oestrogens.
Rowland I, Faughnan M, Hoey L, Wähälä K, Williamson G, Cassidy A. Rowland I, et al. Br J Nutr. 2003 Jun;89 Suppl 1:S45-58. doi: 10.1079/BJN2002796. Br J Nutr. 2003. PMID: 12725656 Review.
The term phyto-oestrogen encompasses isoflavone compounds, such as genistein and daidzein, found predominantly in soya products and the lignans, such as matairesinol and secoisolariciresinol, found in many fruits, cereals and in flaxseed. ...
The term phyto-oestrogen encompasses isoflavone compounds, such as genistein and daidzein, found predominantly in soya products and the lign …
Phytoestrogens and risk of prostate cancer: an updated meta-analysis of epidemiologic studies.
Zhang Q, Feng H, Qluwakemi B, Wang J, Yao S, Cheng G, Xu H, Qiu H, Zhu L, Yuan M. Zhang Q, et al. Int J Food Sci Nutr. 2017 Feb;68(1):28-42. doi: 10.1080/09637486.2016.1216525. Epub 2016 Aug 9. Int J Food Sci Nutr. 2017. PMID: 27687296 Review.
Analytical results showed that daidzein (OR = 0.85; 95% CI: 0.75-0.96), genistein (OR = 0.87; 95% CI: 0.78-0.98), and glycitein (OR = 0.89; 95% CI: 0.81-0.98) were associated with a reduction of prostate cancer risk, but total isoflavones (OR = 0.93; 95% CI: 0.84-1.04), equol (OR …
Analytical results showed that daidzein (OR = 0.85; 95% CI: 0.75-0.96), genistein (OR = 0.87; 95% CI: 0.78-0.98), and glycitein (OR = 0.89; …
Effects of in vitro exposure of sheep ovarian tissue to zearalenone and matairesinol on preantral follicles.
Brito DCC, Silva IP, Ferreira ACA, Sá NAR, Guedes MIF, Rodrigues APR, Santos RR, Figueiredo JR. Brito DCC, et al. Zygote. 2022 Jun;30(3):419-422. doi: 10.1017/S0967199421000794. Epub 2021 Oct 25. Zygote. 2022. PMID: 34689852
The aim of this study was to evaluate the effect of 1 mol/l zearalenone (ZEN) and 1 mol/l matairesinol (MAT), alone or in combination, on the morphology of in vitro-cultured ovarian preantral follicles. ...
The aim of this study was to evaluate the effect of 1 mol/l zearalenone (ZEN) and 1 mol/l matairesinol (MAT), alone or in combination …
IgE-suppressive activity of (-)-matairesinol and its structure-activity relationship.
Kawahara S, Iwata I, Fujita E, Yamawaki M, Nishiwaki H, Sugahara T, Yamauchi S, Akiyama K, Kishida T. Kawahara S, et al. Biosci Biotechnol Biochem. 2010;74(9):1878-83. doi: 10.1271/bbb.100275. Epub 2010 Sep 7. Biosci Biotechnol Biochem. 2010. PMID: 20834158 Free article.
The IgE-suppressive activity of (-)-matairesinol is demonstrated, and the structure-activity relationship of (-)-matairesinol clarified. 3',4-Dihydroxy-3,4'-dimethoxylignano-9,9'-lactone showed higher IgE-suppressive activity than (-)-matairesinol without any …
The IgE-suppressive activity of (-)-matairesinol is demonstrated, and the structure-activity relationship of (-)-matairesinol …
Origin of Wine Lignans.
Dadáková K, Jurasová L, Kašparovský T, Průšová B, Baroň M, Sochor J. Dadáková K, et al. Plant Foods Hum Nutr. 2021 Dec;76(4):472-477. doi: 10.1007/s11130-021-00928-1. Epub 2021 Oct 9. Plant Foods Hum Nutr. 2021. PMID: 34626324
Generally, white wines aged in stainless steel tanks contained only low amounts of isolariciresinol and matairesinol. Qvevri wines and red wine aged in stainless steel tank contained up to five lignan compounds and in wine aged in oak barrel, six different lignans were ide …
Generally, white wines aged in stainless steel tanks contained only low amounts of isolariciresinol and matairesinol. Qvevri wines an …
Cytotoxicity of arctigenin and matairesinol against the T-cell lymphoma cell line CCRF-CEM.
Su S, Cheng X, Wink M. Su S, et al. J Pharm Pharmacol. 2015 Sep;67(9):1316-23. doi: 10.1111/jphp.12426. Epub 2015 Apr 29. J Pharm Pharmacol. 2015. PMID: 25922263
OBJECTIVES: Arctigenin and matairesinol possess a diversity of bioactivities. Here we investigated the cytotoxicity of arctigenin and matairesinol against a T-cell lymphoma cell line CCRF-CEM and the underlying mechanisms that have not been explored before. ...CONCL …
OBJECTIVES: Arctigenin and matairesinol possess a diversity of bioactivities. Here we investigated the cytotoxicity of arctigenin and …
315 results