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1967 1
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Page 1
Pharmacokinetics and metabolism study of isoboldine, a major bioactive component from Radix Linderae in male rats by UPLC-MS/MS.
Li Y, Zeng RJ, Chen JZ, Wu YB, Chou GX, Gao Y, Shao JW, Cai HZ, Jia L. Li Y, et al. J Ethnopharmacol. 2015 Aug 2;171:154-60. doi: 10.1016/j.jep.2015.05.042. Epub 2015 Jun 6. J Ethnopharmacol. 2015. PMID: 26055342
MATERIALS AND METHODS: In this study, a sensitive and simple UPLC-MS/MS method was developed and validated for determination of isoboldine in rat plasma. Isoboldine in plasma was recovered by liquid-liquid extraction using 1 mL of methyl tert-butyl ether. ...A total …
MATERIALS AND METHODS: In this study, a sensitive and simple UPLC-MS/MS method was developed and validated for determination of isoboldin …
Isoboldine and lupenone from Neolitsea fuscata.
Leslie Gunatilaka AA, Sotheeswaran S, Sriyani B, Balasubramaniam S. Leslie Gunatilaka AA, et al. Planta Med. 1981 Nov;43(11):309-10. doi: 10.1055/s-2007-971517. Planta Med. 1981. PMID: 17402053 No abstract available.
Anti-inflammatory principles from Lindera aggregata.
Kuo PC, Wu YH, Hung HY, Lam SH, Ma GH, Kuo LM, Hwang TL, Kuo DH, Wu TS. Kuo PC, et al. Bioorg Med Chem Lett. 2020 Jul 1;30(13):127224. doi: 10.1016/j.bmcl.2020.127224. Epub 2020 Apr 27. Bioorg Med Chem Lett. 2020. PMID: 32359855
Among the tested compounds, linderaggredin C (3), (+)-N-methyllaurotetanine, and (+)-isoboldine displayed the significant inhibition of superoxide anion generation in human neutrophils with IC(50) values of 7.45 0.74, 8.36 0.11, and 5.81 0.59 muM, respectively....
Among the tested compounds, linderaggredin C (3), (+)-N-methyllaurotetanine, and (+)-isoboldine displayed the significant inhibition …
Opium alkaloids. IV. Isolation of isoboldine.
Brochmann-Hanssen E, Nielsen B, Hirai K. Brochmann-Hanssen E, et al. J Pharm Sci. 1967 Jun;56(6):754-6. doi: 10.1002/jps.2600560621. J Pharm Sci. 1967. PMID: 6034811 No abstract available.
[Chemical constituents in chloroform fraction of Houttuynia cordata].
Yang XL, Yang YP, Ge YW, Meng J. Yang XL, et al. Zhongguo Zhong Yao Za Zhi. 2019 Jan;44(2):314-318. doi: 10.19540/j.cnki.cjcmm.2019.0007. Zhongguo Zhong Yao Za Zhi. 2019. PMID: 30989951 Chinese.
Nine compounds were isolated from chloroform fraction of Houttuynia cordata,and the isolates were identified as follows:( S)-5,6,6 a,7-tetrahydro-2,10-dimethoxy-4 H-dibenzo [DE,G] quinoline-1,9-diol( 1),( +)-isoboldine beta-N-oxide( 2),liriotulipiferine( 3),telitoxinone( 4 …
Nine compounds were isolated from chloroform fraction of Houttuynia cordata,and the isolates were identified as follows:( S)-5,6,6 a,7-tetra …
Alkaloids from Corydalis bulbosa.
Kiryakov HG, Iskrenova E, Kuzmanov B, Evstatieva L. Kiryakov HG, et al. Planta Med. 1981 Sep;43(1):51-5. doi: 10.1055/s-2007-971472. Planta Med. 1981. PMID: 17402008
Dc (Papaveraceae), together with dehydronantenine, (-)-stylopine, (+)-bicuculline, (-)-adlumidine, (+)-nantenine, (+)-bulbocapnine, protopine (-)-domesticine, (+)-corydine, predicentrine, oxonantenine, (+)-isoboldine and nandazurine. Glaucine and thaliporphine were detecte …
Dc (Papaveraceae), together with dehydronantenine, (-)-stylopine, (+)-bicuculline, (-)-adlumidine, (+)-nantenine, (+)-bulbocapnine, protopin …
Rat CYP2D2, not 2D1, is functionally conserved with human CYP2D6 in endogenous morphine formation.
Grobe N, Kutchan TM, Zenk MH. Grobe N, et al. FEBS Lett. 2012 Jun 21;586(13):1749-53. doi: 10.1016/j.febslet.2012.05.021. Epub 2012 May 26. FEBS Lett. 2012. PMID: 22641033 Free PMC article.
In addition, CYP2D2 incubated with (R)-reticuline generated four products corytuberine, pallidine, salutaridine and isoboldine while rat CYP2D1 was completely inactive. This intramolecular phenol-coupling reaction follows the same mechanism as observed for CYP2D6. ...
In addition, CYP2D2 incubated with (R)-reticuline generated four products corytuberine, pallidine, salutaridine and isoboldine while …
Additional alkaloids of Pachygone ovata.
El-Kawi MA, Slatkin DJ, Schiff PL Jr, Dasgupta S, Chattopadhyay SK, Ray AB. El-Kawi MA, et al. J Nat Prod. 1984 May-Jun;47(3):459-64. doi: 10.1021/np50033a010. J Nat Prod. 1984. PMID: 6481360
Chromatography of the extract of the roots resulted in the reisolation of the alkaloids liriodenine, coclaurine, trilobine (1), and magnoflorine and the isolation of stepholidine, coreximine, isoboldine, norjuziphine, and nortrilobine (2). Nortrilobine (2) is a new dibenzo …
Chromatography of the extract of the roots resulted in the reisolation of the alkaloids liriodenine, coclaurine, trilobine (1), and magnoflo …
36 results