Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1993 1
1995 1
1996 1
1998 2
1999 2
2000 1
2001 2
2002 3
2003 2
2005 2
2006 2
2007 2
2008 6
2009 3
2010 1
2012 1
2014 1
2015 4
2016 2
2017 2
2020 1
2024 0

Text availability

Article attribute

Article type

Publication date

Search Results

40 results

Results by year

Filters applied: . Clear all
Page 1
Sensitization to 26 fragrances to be labelled according to current European regulation. Results of the IVDK and review of the literature.
Schnuch A, Uter W, Geier J, Lessmann H, Frosch PJ. Schnuch A, et al. Contact Dermatitis. 2007 Jul;57(1):1-10. doi: 10.1111/j.1600-0536.2007.01088.x. Contact Dermatitis. 2007. PMID: 17577350 Review.
The following frequencies of sensitization (rates in %, standardized for sex and age) were observed: tree moss (2.4%), HMPCC (2.3), oak moss (2.0), hydroxycitronellal (1.3), isoeugenol (1.1), cinnamic aldehyde (1.0), farnesol (0.9), cinnamic alcohol (0.6), citral (0.6), citronell …
The following frequencies of sensitization (rates in %, standardized for sex and age) were observed: tree moss (2.4%), HMPCC (2.3), oak moss …
Intra-laboratory study to determine the reproducibility of LLNA:BrdU-ELISA for the prediction of the skin sensitizing potential of chemicals.
Chen W, Xing C, Hou F. Chen W, et al. J Pharmacol Toxicol Methods. 2016 Nov-Dec;82:26-30. doi: 10.1016/j.vascn.2016.07.003. Epub 2016 Jul 22. J Pharmacol Toxicol Methods. 2016. PMID: 27456929
METHODS: Ten independent LLNA:BrdU-ELISAs with the preferred positive controls (PCs), i.e., 25% hexyl cinnamic aldehyde (HCA) and 25% eugenol, were conducted within a period of less than one year. ...
METHODS: Ten independent LLNA:BrdU-ELISAs with the preferred positive controls (PCs), i.e., 25% hexyl cinnamic aldehyde …
Skin sensitisation testing--new perspectives and recommendations.
Steiling W, Basketter D, Berthold K, Butler M, Garrigue JL, Kimber I, Lea L, Newsome C, Roggeband R, Stropp G, Waterman S, Wiemann C. Steiling W, et al. Food Chem Toxicol. 2001 Apr;39(4):293-301. doi: 10.1016/s0278-6915(00)00147-2. Food Chem Toxicol. 2001. PMID: 11295477 Review.
An optional scheme for the conduct of joint positive control studies within a co-ordinated group of laboratories is appropriate. Only one positive control chemical (alpha-hexyl cinnamic aldehyde) is necessary for the routine assessment of assay sensitivity. . …
An optional scheme for the conduct of joint positive control studies within a co-ordinated group of laboratories is appropriate. Only one po …
The suitability of hexyl cinnamic aldehyde as a calibrant for the murine local lymph node assay.
Dearman RJ, Wright ZM, Basketter DA, Ryan CA, Gerberick GF, Kimber I. Dearman RJ, et al. Contact Dermatitis. 2001 Jun;44(6):357-61. doi: 10.1034/j.1600-0536.2001.044006357.x. Contact Dermatitis. 2001. PMID: 11380546
This method has been endorsed recently as a stand alone test for the identification of contact allergens. We have now examined the suitability of hexyl cinnamic aldehyde (HCA), a recommended positive control for skin sensitization testing, as a calibrant for …
This method has been endorsed recently as a stand alone test for the identification of contact allergens. We have now examined the suitabili …
An improvement of LLNA:DA to assess the skin sensitization potential of chemicals.
Zhang H, Shi Y, Wang C, Zhao K, Zhang S, Wei L, Dong L, Gu W, Xu Y, Ruan H, Zhi H, Yang X. Zhang H, et al. J Toxicol Sci. 2017;42(2):129-136. doi: 10.2131/jts.42.129. J Toxicol Sci. 2017. PMID: 28321039 Free article.
In the second stage, sodium lauryl sulphate and xylene were classified as weak sensitizers. a-hexyl cinnamic aldehyde and eugenol were moderate sensitizers. Benzalkonium chloride and glyoxal were strong sensitizers, and phthalic anhydride was an extreme sensi …
In the second stage, sodium lauryl sulphate and xylene were classified as weak sensitizers. a-hexyl cinnamic aldehyde a …
Performance standard-based validation study for local lymph node assay: 5-bromo-2-deoxyuridine-flow cytometry method.
Ahn I, Kim TS, Jung ES, Yi JS, Jang WH, Jung KM, Park M, Jung MS, Jeon EY, Yeo KU, Jo JH, Park JE, Kim CY, Park YC, Seong WK, Lee AY, Chun YJ, Jeong TC, Jeung EB, Lim KM, Bae S, Sohn S, Heo Y. Ahn I, et al. Regul Toxicol Pharmacol. 2016 Oct;80:183-94. doi: 10.1016/j.yrtph.2016.06.009. Epub 2016 Jun 16. Regul Toxicol Pharmacol. 2016. PMID: 27318101
Transferability was demonstrated through successfully producing stimulation index (SI) values for 25% hexyl cinnamic aldehyde (HCA) consistently greater than 3, a predetermined threshold, by all participating laboratories. ...
Transferability was demonstrated through successfully producing stimulation index (SI) values for 25% hexyl cinnamic aldehy …
Temporal stability of local lymph node assay responses to hexyl cinnamic aldehyde.
Dearman RJ, Hilton J, Evans P, Harvey P, Basketter DA, Kimber I. Dearman RJ, et al. J Appl Toxicol. 1998 Jul-Aug;18(4):281-4. doi: 10.1002/(sici)1099-1263(199807/08)18:4<281::aid-jat506>3.0.co;2-4. J Appl Toxicol. 1998. PMID: 9719428
It was the purpose of the investigations described here to consider this issue and, to this end, responses provoked in the local lymph node assay by hexyl cinnamic aldehyde (HCA)--a skin sensitizing chemical of moderate potency--were assessed in five separate …
It was the purpose of the investigations described here to consider this issue and, to this end, responses provoked in the local lymph node …
Suitability of macrophage inflammatory protein-1beta production by THP-1 cells in differentiating skin sensitizers from irritant chemicals.
Lim YM, Moon SJ, An SS, Lee SJ, Kim SY, Chang IS, Park KL, Kim HA, Heo Y. Lim YM, et al. Contact Dermatitis. 2008 Apr;58(4):193-8. doi: 10.1111/j.1600-0536.2007.01311.x. Contact Dermatitis. 2008. PMID: 18353026
RESULTS AND CONCLUSION: When the threshold MIP-1beta production rate used was 100% or 105% of dimethyl sulfoxide, all the sensitizing chemicals tested (dinitrochlorobenzene, hexyl cinnamic aldehyde, eugenol, hydroquinone, dinitrofluorobenzene, benzocaine, nic …
RESULTS AND CONCLUSION: When the threshold MIP-1beta production rate used was 100% or 105% of dimethyl sulfoxide, all the sensitizing chemic …
Gene expression profiles in auricle skin as a possible additional endpoint for determination of sensitizers: A multi-endpoint evaluation of the local lymph node assay.
Tsuchiyama H, Maeda A, Nakajima M, Kitsukawa M, Takahashi K, Miyoshi T, Mutsuga M, Asaoka Y, Miyamoto Y, Oshida K. Tsuchiyama H, et al. Toxicol Lett. 2017 Oct 5;280:133-141. doi: 10.1016/j.toxlet.2017.08.009. Epub 2017 Aug 18. Toxicol Lett. 2017. PMID: 28826779
In search of a potential endpoint to enhance the specificity of existing endpoints, we evaluated 3 contact sensitizers; (hexyl cinnamic aldehyde [HCA], oxazolone [OXA], and 2,4-dinitrochlorobenzene [DNCB]), 1 respiratory sensitizer (toluene 2,4-diisocyanate [ …
In search of a potential endpoint to enhance the specificity of existing endpoints, we evaluated 3 contact sensitizers; (hexyl cin …
40 results