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Pharmacological studies of furo [3,2-b] indole derivatives. I. Analgesic, anti-pyretic and anti-inflammatory effects of FI-302, N-(3-piperidinopropyl)-4-methyl-6-trifluoromethyl-furo [3,2-b]indole-2-carboxamide, in experimental animals.
Kameyama T, Amanuma F, Okuyama S, Higuchi S, Aihara H. Kameyama T, et al. J Pharmacobiodyn. 1985 Jun;8(6):477-86. doi: 10.1248/bpb1978.8.477. J Pharmacobiodyn. 1985. PMID: 3877158
FI-302 showed potent analgesic and antipyretic effects in the various models used. ...Moreover, FI-302 had little or no ulcerogenic activity. From these results, it is conceivable that the spectrum of FI-302's activities is similar to tho …
FI-302 showed potent analgesic and antipyretic effects in the various models used. ...Moreover, FI-302 had littl …
Pharmacological studies of furo [3,2-b]indole derivatives. II. Analgesic effect of FI-302, N-(3-piperidinopropyl)-4-methyl-6-trifluoromethyl-furo[3,2-b]ind ole-2-carboxamide, in experimental animals.
Amanuma F, Okuyama S, Aihara H, Kameyama T. Amanuma F, et al. J Pharmacobiodyn. 1985 Aug;8(8):687-93. doi: 10.1248/bpb1978.8.687. J Pharmacobiodyn. 1985. PMID: 3878869
However, the analgesic effect of FI-302 was not antagonized by levallorphan. From these results, it appears that FI-302 has potent analgesic effects which may be produced by both peripheral and central mechanisms, but it is a non-narcotic compound. Con …
However, the analgesic effect of FI-302 was not antagonized by levallorphan. From these results, it appears that FI- …