Two automated locomotor activity tests for dopamine autoreceptor agonists.
Schreur PJ, Nichols NF.
Schreur PJ, et al.
Pharmacol Biochem Behav. 1986 Jul;25(1):255-61. doi: 10.1016/0091-3057(86)90263-7.
Pharmacol Biochem Behav. 1986.
PMID: 2875471
Apomorphine HCl, NPA, and (+)3-PPP antagonized amphetamine-stimulated locomotor behavior (total distance) without antagonizing apomorphine-stimulated behavior, suggesting a presynaptic dopamine autoreceptor agonism. EMD 23448 gave equivocal activity. On the other ha …
Apomorphine HCl, NPA, and (+)3-PPP antagonized amphetamine-stimulated locomotor behavior (total distance) without antagonizing apomorphine-s …