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Page 1
Interaction of pyrethroids with the Na+ channel in mammalian neuronal cells in culture.
Jacques Y, Romey G, Cavey MT, Kartalovski B, Lazdunski M. Jacques Y, et al. Biochim Biophys Acta. 1980 Aug 14;600(3):882-97. doi: 10.1016/0005-2736(80)90491-5. Biochim Biophys Acta. 1980. PMID: 6250606
However, they stimulate 22Na+ entry when used in conjunction with other toxins specific for the gating system of the channel. These include batrachotoxin, veratridine, dihydrograyanotoxin II or polypeptide toxins like sea anemone and scorpion toxins. ...The synergis …
However, they stimulate 22Na+ entry when used in conjunction with other toxins specific for the gating system of the channel. These include …
Effect of grayanotoxin on the frog neuromuscular junction.
Zushi S, Miyagawa J, Yamamoto M, Kataoka K, Seyama I. Zushi S, et al. J Pharmacol Exp Ther. 1983 Jul;226(1):269-75. J Pharmacol Exp Ther. 1983. PMID: 6864545
The effect of alpha-dihydrograyanotoxin II (alpha-H2-GTX II) on the neuromuscular junction of the frog was examined by the intracellular microelectrode technique. alpha-H2-GTX II (6 microM), with a latency of about 20 min, caused a depolarization of both the end-pla …
The effect of alpha-dihydrograyanotoxin II (alpha-H2-GTX II) on the neuromuscular junction of the frog was examined by the int …
The effects of grayanotoxin I and alpha-dihydrograyanotoxin II on guinea-pig myocardium.
Ku DD, Akera T, Frank M, Brody TM, Iwasa J. Ku DD, et al. J Pharmacol Exp Ther. 1977 Feb;200(2):363-72. J Pharmacol Exp Ther. 1977. PMID: 138734
In order to determine whether this effect of GTX I is related to the reported action of this compound to increase the sodium permeability of cytoplasmic membranes, the effect of GTX I and alpha-dihydrograyanotoxin II (alpha-2H-GTX II) on electrical and mechanical pr …
In order to determine whether this effect of GTX I is related to the reported action of this compound to increase the sodium permeability of …
Evidence that alpha-dihydrograyanotoxin II does not bind to the sodium gate.
Soeda Y, O'Brien RD, Yeh JZ, Narahashi T. Soeda Y, et al. J Membr Biol. 1975 Aug 11;23(1):91-101. doi: 10.1007/BF01870246. J Membr Biol. 1975. PMID: 1165582
The basis for the ability of alpha-dihydrograyanotoxin II (alpha-2HG-II) to promote Na+ conductance in axons was sought. ...
The basis for the ability of alpha-dihydrograyanotoxin II (alpha-2HG-II) to promote Na+ conductance in axons was sought. ...
Modulation of nerve membrane sodium channels by chemicals.
Narahashi T. Narahashi T. J Physiol (Paris). 1981 May;77(9):1093-101. J Physiol (Paris). 1981. PMID: 6286960
Modulations of sodium channel kinetics by grayanotoxins and pyrethroids have been studied using voltage clamped, internally perfused giant axons from crayfish and squid. 2. Grayanotoxin I and alpha-dihydrograyanotoxin II greatly depolarize the nerve membrane through …
Modulations of sodium channel kinetics by grayanotoxins and pyrethroids have been studied using voltage clamped, internally perfused giant a …
Sensitivity of excitable and inexcitable membranes to alpha-dihydrograyanotoxin II.
Starkus JG, Narahashi T. Starkus JG, et al. Am J Physiol. 1978 Nov;235(5):C204-11. doi: 10.1152/ajpcell.1978.235.5.C204. Am J Physiol. 1978. PMID: 727243
A variety of excitable and inexcitable preparations have been examined for their sensitivity to the depolarizing action of alpha-dihydrograyanotoxin II. alpha-Dihydrograyanotoxin II was effective in producing membrane depolarization in giant axons from …
A variety of excitable and inexcitable preparations have been examined for their sensitivity to the depolarizing action of alpha-dihydrog
Kinetics of grayanotoxin evoked modification of sodium channels in squid giant axons.
Yakehiro M, Seyama I, Narahashi T. Yakehiro M, et al. Pflugers Arch. 1997 Feb;433(4):403-12. Pflugers Arch. 1997. PMID: 9082327
Kinetics of modification of the sodium channel by alpha-dihydrograyanotoxin II (GTX) were studied with voltage-clamped squid giant axons. ...
Kinetics of modification of the sodium channel by alpha-dihydrograyanotoxin II (GTX) were studied with voltage-clamped squid g …