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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1950 1
1952 2
1955 1
1959 2
1960 3
1961 4
1962 3
1963 6
1964 5
1965 4
1966 5
1967 8
1968 9
1969 3
1970 10
1971 7
1972 7
1973 7
1974 5
1975 14
1976 12
1977 4
1978 7
1979 9
1980 5
1981 8
1982 5
1983 7
1984 7
1985 6
1986 4
1987 10
1988 20
1989 31
1990 52
1991 31
1992 30
1993 25
1994 35
1995 34
1996 25
1997 32
1998 36
1999 26
2000 30
2001 23
2002 34
2003 39
2004 59
2005 69
2006 91
2007 78
2008 80
2009 93
2010 96
2011 101
2012 136
2013 112
2014 99
2015 106
2016 102
2017 118
2018 106
2019 93
2020 103
2021 100
2022 93
2023 99
2024 39

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2,396 results

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Page 1
D-Serine as a sensor and effector of the kidney.
Kimura T, Sakai S, Isaka Y. Kimura T, et al. Clin Exp Nephrol. 2023 Nov;27(11):891-900. doi: 10.1007/s10157-023-02384-4. Epub 2023 Jul 27. Clin Exp Nephrol. 2023. PMID: 37498348 Free PMC article. Review.
D-Serine, a rare enantiomer of serine, is a biomarker of kidney disease and function. ...This feedback system strictly controls D-serine levels in the body. The function of D-serine as a biomarker and modulator of kidney function will be …
D-Serine, a rare enantiomer of serine, is a biomarker of kidney disease and function. ...This feedback system strictly control …
D-Serine: A Cross Species Review of Safety.
Meftah A, Hasegawa H, Kantrowitz JT. Meftah A, et al. Front Psychiatry. 2021 Aug 10;12:726365. doi: 10.3389/fpsyt.2021.726365. eCollection 2021. Front Psychiatry. 2021. PMID: 34447324 Free PMC article. Review.
Based on studies in rats, concerns of nephrotoxicity have limited D-serine research in humans, particularly using high doses. A review of D-serine's safety is timely and pertinent, as D-serine remains under active study for schizophrenia, …
Based on studies in rats, concerns of nephrotoxicity have limited D-serine research in humans, particularly using high doses. …
D-Serine: Potential Therapeutic Agent and/or Biomarker in Schizophrenia and Depression?
MacKay MB, Kravtsenyuk M, Thomas R, Mitchell ND, Dursun SM, Baker GB. MacKay MB, et al. Front Psychiatry. 2019 Feb 6;10:25. doi: 10.3389/fpsyt.2019.00025. eCollection 2019. Front Psychiatry. 2019. PMID: 30787885 Free PMC article. Review.
Clinical studies have been conducted in schizophrenia patients to evaluate body fluid levels of D-serine and/or to use D-serine alone or in combination with antipsychotics to determine its effectiveness as a therapeutic agent. ...Clinical studies have …
Clinical studies have been conducted in schizophrenia patients to evaluate body fluid levels of D-serine and/or to use D …
Utility of d-serine monitoring in kidney disease.
Kimura T, Hesaka A, Isaka Y. Kimura T, et al. Biochim Biophys Acta Proteins Proteom. 2020 Sep;1868(9):140449. doi: 10.1016/j.bbapap.2020.140449. Epub 2020 May 22. Biochim Biophys Acta Proteins Proteom. 2020. PMID: 32450146 Review.
d-Serine, a long-term undetected enantiomer of serine, is now showing its potential as a biomarker for kidney diseases. ...Thus, widespread adoption of d-serine as a biomarker can resolve the long-standing clinical challenge of the early detection and …
d-Serine, a long-term undetected enantiomer of serine, is now showing its potential as a biomarker for kidney diseases. ...Thu …
The Neurobiology of d-Serine Signaling.
Wolosker H. Wolosker H. Adv Pharmacol. 2018;82:325-348. doi: 10.1016/bs.apha.2017.08.010. Epub 2017 Nov 8. Adv Pharmacol. 2018. PMID: 29413526 Review.
d-Serine is a physiological coagonist of NMDA receptors involved in synaptic plasticity, neurodevelopment, and neurodegeneration. d-Serine is synthesized by the enzyme serine racemase, which converts l- to d-serine. ...Serine racemase and …
d-Serine is a physiological coagonist of NMDA receptors involved in synaptic plasticity, neurodevelopment, and neurodegenerati …
D-serine: physiology and pathology.
Radzishevsky I, Sason H, Wolosker H. Radzishevsky I, et al. Curr Opin Clin Nutr Metab Care. 2013 Jan;16(1):72-5. doi: 10.1097/MCO.0b013e32835a3466. Curr Opin Clin Nutr Metab Care. 2013. PMID: 23041616 Review.
Recent data indicate that like glial D-serine, neuronal D-serine is required for NMDAR-dependent, long-term potentiation at the hippocampal CA1-CA3 synapses and proper synapse formation in the cerebral cortex. ...SUMMARY: D-Serine is now …
Recent data indicate that like glial D-serine, neuronal D-serine is required for NMDAR-dependent, long-term pote …
D-Serine in the aging hippocampus.
Billard JM. Billard JM. J Pharm Biomed Anal. 2015 Dec 10;116:18-24. doi: 10.1016/j.jpba.2015.02.013. Epub 2015 Feb 16. J Pharm Biomed Anal. 2015. PMID: 25740810 Review.
This review aims at compelling recent studies characterizing the role of D-serine in changes in functional plasticity that occur in the aging hippocampus since deficits are rescued by D-serine supplementation. ...Interestingly, neither SR expression, …
This review aims at compelling recent studies characterizing the role of D-serine in changes in functional plasticity that occ …
D-serine and schizophrenia: an update.
Nunes EA, MacKenzie EM, Rossolatos D, Perez-Parada J, Baker GB, Dursun SM. Nunes EA, et al. Expert Rev Neurother. 2012 Jul;12(7):801-12. doi: 10.1586/ern.12.65. Expert Rev Neurother. 2012. PMID: 22853788 Review.
A glutamatergic deficit has been proposed to underlie many of the symptoms typically observed in schizophrenia, particularly the negative and cognitive symptoms (which are less likely to respond to current treatments). D-serine is an important coagonist of the gluta …
A glutamatergic deficit has been proposed to underlie many of the symptoms typically observed in schizophrenia, particularly the negative an …
D-Serine in neurobiology: CNS neurotransmission and neuromodulation.
Bardaweel SK, Alzweiri M, Ishaqat AA. Bardaweel SK, et al. Can J Neurol Sci. 2014 Mar;41(2):164-76. doi: 10.1017/s031716710001653x. Can J Neurol Sci. 2014. PMID: 24534026 Review.
However, D- amino acids were recently detected in various living organisms, including mammals. Of these D-amino acids, D-serine has been most extensively studied. D-Serine was found to play an important role as a neurotransmitter in the human central n …
However, D- amino acids were recently detected in various living organisms, including mammals. Of these D-amino acids, D-serine …
The role of D-serine in peripheral tissues.
Montesinos Guevara C, Mani AR. Montesinos Guevara C, et al. Eur J Pharmacol. 2016 Jun 5;780:216-23. doi: 10.1016/j.ejphar.2016.03.054. Epub 2016 Mar 31. Eur J Pharmacol. 2016. PMID: 27038518 Review.
A considerable level of D-serine (a free D-amino acid) was discovered, surprisingly, in the mammalian brain in the early 1990s. Since then, D-serine has been considered to be a co-agonist of glutamate at the glycine site of NMDA receptors. ...
A considerable level of D-serine (a free D-amino acid) was discovered, surprisingly, in the mammalian brain in the early 1990s …
2,396 results