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Page 1
Repurposing some of the Well-known Non-steroid Anti-inflammatory Drugs (NSAIDs) for Cancer Treatment.
Sousa SM, Xavier CPR, Vasconcelos MH, Palmeira A. Sousa SM, et al. Curr Top Med Chem. 2023;23(13):1171-1195. doi: 10.2174/1568026623666230130150029. Curr Top Med Chem. 2023. PMID: 36717997 Review.
Indeed, several commercial anti-inflammatory drugs, including aspirin, ibuprofen, diclofenac, celecoxib, tepoxalin and cyclovalone, naproxen, and indomethacin have presented antitumor activity, and some of them are already in clinical trials for cancer treatment. ...
Indeed, several commercial anti-inflammatory drugs, including aspirin, ibuprofen, diclofenac, celecoxib, tepoxalin and cyclovalone, n …
Elucidation of the relationships between H-bonding patterns and excited state dynamics in cyclovalone.
Lamperti M, Maspero A, Tønnesen HH, Bondani M, Nardo L. Lamperti M, et al. Molecules. 2014 Aug 28;19(9):13282-304. doi: 10.3390/molecules190913282. Molecules. 2014. PMID: 25170950 Free PMC article.
Cyclovalone is a synthetic curcumin derivative in which the keto-enolic system is replaced by a cyclohexanone ring. ...Moreover, we discuss steady state and time-resolved fluorescence data that aim at characterizing the excited-state dynamics of cyclovalone, and we …
Cyclovalone is a synthetic curcumin derivative in which the keto-enolic system is replaced by a cyclohexanone ring. ...Moreover, we d …
[Portal hypertension and hypervitaminosis A. Apropos of 2 cases and review of the literature].
Dubois A, Balducchi JP, Barbuat C, Fabre J, Flaisler F, Joujoux JM, Pignodel C, Jourdan J, Fourcade J. Dubois A, et al. Rev Med Interne. 1991 Jul-Aug;12(4):295-8. doi: 10.1016/s0248-8663(05)82867-x. Rev Med Interne. 1991. PMID: 1759070 Review. French.
In the second case, a 43-year old woman had absorbed Plethoryl (a combination of tiratricol, cyclovalone and retinol) in order to lose weight. Both patients had histological hepatic lesions, such as hypertrophic Ito cells, perisinusoidal cirrhosis and spontaneous autofluor …
In the second case, a 43-year old woman had absorbed Plethoryl (a combination of tiratricol, cyclovalone and retinol) in order to los …
Type II [3H]estradiol binding site antagonists: inhibition of normal and malignant prostate cell growth and proliferation.
Markaverich BM, Alejandro MA. Markaverich BM, et al. Int J Oncol. 1998 May;12(5):1127-35. doi: 10.3892/ijo.12.5.1127. Int J Oncol. 1998. PMID: 9538139
Therefore, we assessed the effects of 2,6-bis((3-methoxy-4-hydroxyphenyl)-methylene)-cyclohexanone (BMHPC) on normal and malignant prostatic cell growth and proliferation in vitro and in vivo. This cyclovalone is designed to bind to type II sites with high affinity and mim …
Therefore, we assessed the effects of 2,6-bis((3-methoxy-4-hydroxyphenyl)-methylene)-cyclohexanone (BMHPC) on normal and malignant prostatic …
[Probable side effects caused by plethoryl. Common acute hepatitis, anicteric hepatitis, cirrhosis due to hypervitaminosis A, inflammatory arthralgias].
Maroy B, Moullot P, Constantin JM. Maroy B, et al. Presse Med. 1989 Mar 18;18(11):567-70. Presse Med. 1989. PMID: 2523055 French.
Plethoryl is a combination of triatricol, cyclovalone and vitamin A normally prescribed in the treatment of hypercholesterolaemia. ...
Plethoryl is a combination of triatricol, cyclovalone and vitamin A normally prescribed in the treatment of hypercholesterolaemia. .. …
[Substituted methoxyphenol with antioxidative activity: correlation between physicochemical and biological results].
Souchard JP, Limasset B, Michel F, Crastes de Paulet A, Labidalle S, Nepveu F. Souchard JP, et al. C R Seances Soc Biol Fil. 1995;189(6):1171-81. C R Seances Soc Biol Fil. 1995. PMID: 8763040 French.
Platelet cycloxygenase activity was inhibited by curcumin and cyclovalone. ESR studies showed a better ROS scavenging activity for vanillin, methyl ferulate and curcumin. ...
Platelet cycloxygenase activity was inhibited by curcumin and cyclovalone. ESR studies showed a better ROS scavenging activity for va …
11 results