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Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1953 1
1958 2
1963 9
1964 19
1965 14
1969 1
1970 7
1971 10
1972 11
1973 10
1974 24
1975 20
1976 16
1977 17
1978 32
1979 18
1980 15
1981 32
1982 21
1983 29
1984 26
1985 32
1986 24
1987 43
1988 30
1989 31
1990 20
1991 18
1992 21
1993 13
1994 10
1995 16
1996 13
1997 15
1998 24
1999 14
2000 22
2001 20
2002 17
2003 16
2004 17
2005 24
2006 22
2007 33
2008 37
2009 33
2010 35
2011 35
2012 40
2013 27
2014 28
2015 29
2016 22
2017 29
2018 27
2019 31
2020 48
2021 34
2022 31
2023 31
2024 11

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1,288 results

Results by year

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Page 1
Bromhexine.
Sehgal SK, Mohan M. Sehgal SK, et al. Indian Pediatr. 1990 May;27(5):479-83. Indian Pediatr. 1990. PMID: 2276776 Review. No abstract available.
Mucolytics for bronchiectasis.
Wilkinson M, Sugumar K, Milan SJ, Hart A, Crockett A, Crossingham I. Wilkinson M, et al. Cochrane Database Syst Rev. 2014 May 2;2014(5):CD001289. doi: 10.1002/14651858.CD001289.pub2. Cochrane Database Syst Rev. 2014. PMID: 24789119 Free PMC article. Review.
A reduction in sputum production was noted with bromhexine (MD -21.5%, 95% CI -38.9 to -4.1 at day 16); again the quality of the evidence was rated as low. ...As the number of agents available on the market, such as RhDNase, acetylcysteine and bromhexine, is increas …
A reduction in sputum production was noted with bromhexine (MD -21.5%, 95% CI -38.9 to -4.1 at day 16); again the quality of the evid …
Mucolytics for bronchiectasis.
Crockett AJ, Cranston JM, Latimer KM, Alpers JH. Crockett AJ, et al. Cochrane Database Syst Rev. 2001;(1):CD001289. doi: 10.1002/14651858.CD001289. Cochrane Database Syst Rev. 2001. PMID: 11279712 Updated. Review.
There was also a reduction in sputum production with bromhexine (weighted mean difference -21.5%, 95% confidence interval -38.9 to -4.1 % at day 16). ...REVIEWER'S CONCLUSIONS: There is not enough evidence to evaluate the routine use of mucolytics for bronchiectasis. High …
There was also a reduction in sputum production with bromhexine (weighted mean difference -21.5%, 95% confidence interval -38.9 to -4 …
Effect of bromhexine in hospitalized patients with COVID-19.
Tolouian R, Mulla ZD, Jamaati H, Babamahmoodi A, Marjani M, Eskandari R, Dastan F. Tolouian R, et al. J Investig Med. 2023 Oct;71(7):691-699. doi: 10.1136/jim-2020-001747. J Investig Med. 2023. PMID: 33722999 Clinical Trial.
BACKGROUND: Bromhexine is a potent inhibitor of transmembrane serine protease 2 and appears to have an antiviral effect in controlling influenza and parainfluenza infection; however, its efficacy in COVID-19 is controversial. ...The potential prevention benefits of brom …
BACKGROUND: Bromhexine is a potent inhibitor of transmembrane serine protease 2 and appears to have an antiviral effect in controllin …
FARMER'S lung.
[No authors listed] [No authors listed] Lancet. 1953 May 9;1(6767):937. Lancet. 1953. PMID: 13045463 No abstract available.
Mucolytics for bronchiectasis.
Crockett AJ, Cranston JM, Latimer KM, Alpers JH. Crockett AJ, et al. Cochrane Database Syst Rev. 2000;(2):CD001289. doi: 10.1002/14651858.CD001289. Cochrane Database Syst Rev. 2000. PMID: 10796636 Updated. Review.
There was also a reduction in sputum production with bromhexine (weighted mean difference -21.5%, 95% confidence interval -38.9 to -4.1 at day 16). ...REVIEWER'S CONCLUSIONS: There is not enough evidence to evaluate the routine use of mucolytics for bronchiectasis. High do …
There was also a reduction in sputum production with bromhexine (weighted mean difference -21.5%, 95% confidence interval -38.9 to -4 …
Potential new treatment strategies for COVID-19: is there a role for bromhexine as add-on therapy?
Depfenhart M, de Villiers D, Lemperle G, Meyer M, Di Somma S. Depfenhart M, et al. Intern Emerg Med. 2020 Aug;15(5):801-812. doi: 10.1007/s11739-020-02383-3. Epub 2020 May 26. Intern Emerg Med. 2020. PMID: 32458206 Free PMC article. Review.
An effective prophylactic medication to prevent viral entry has to contain, at least, either a protease inhibitor or a competitive virus ACE2-binding inhibitor. Using bromhexine at a dosage that selectively inhibits TMPRSS2 and, in so doing, inhibits TMPRSS2-specific viral …
An effective prophylactic medication to prevent viral entry has to contain, at least, either a protease inhibitor or a competitive virus ACE …
Enhancement of lung levels of antibiotics by ambroxol and bromhexine.
Deretic V, Timmins GS. Deretic V, et al. Expert Opin Drug Metab Toxicol. 2019 Mar;15(3):213-218. doi: 10.1080/17425255.2019.1578748. Epub 2019 Feb 7. Expert Opin Drug Metab Toxicol. 2019. PMID: 30721101 Free PMC article. Review.
Areas covered: This review discusses preclinical and clinical studies of the effects of ambroxol (and its prodrug precursor bromhexine) co-treatment upon levels of antibiotics in lung tissue, sputum, and bronchoalveolar lavage fluid. ...
Areas covered: This review discusses preclinical and clinical studies of the effects of ambroxol (and its prodrug precursor bromhexine …
Predicting prognosis in idiopathic pulmonary fibrosis.
Barlo NP, van Moorsel CH, van den Bosch JM, Grutters JC. Barlo NP, et al. Sarcoidosis Vasc Diffuse Lung Dis. 2010 Jul;27(2):85-95. Sarcoidosis Vasc Diffuse Lung Dis. 2010. PMID: 21319590 Review.
Cyclodextrins: Efficient biocompatible solubilizing excipients for bromhexine liquid and semi-solid drug delivery systems.
Stojanov M, Nielsen HM, Larsen KL. Stojanov M, et al. Int J Pharm. 2012 Jan 17;422(1-2):349-55. doi: 10.1016/j.ijpharm.2011.10.023. Epub 2011 Oct 17. Int J Pharm. 2012. PMID: 22027391
Bromhexine hydrochloride (bromhexine) is a mucolytic agent with very low aqueous solubility. ...From phase solubility diagrams with alpha-, beta-, gamma- and SBE-beta-CD and bromhexine, it was determined that the solubility of bromhexine significantly …
Bromhexine hydrochloride (bromhexine) is a mucolytic agent with very low aqueous solubility. ...From phase solubility diagrams …
1,288 results