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Year Number of Results
1977 2
1979 1
1981 2
1982 2
1983 2
1985 1
2000 1
2024 0

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Page 1
Synthesis and pharmacological activity of befuraline (N-benzo[b]furan-2-ylcarbonyl-N'-benzylpiperazine), a new antidepressant compound.
Boksay IJ, Popendiker K, Weber RO, Söder A. Boksay IJ, et al. Arzneimittelforschung. 1979;29(2):193-204. Arzneimittelforschung. 1979. PMID: 582130
The methods of synthesis and the pharmacological evaluation of a new non-tricyclic antidepressant drug, N-benzo[b]furan-2-ylcarbonyl-N'-benzylpiperazine (befuraline), are reported. The chemical structure of befuraline is clearly different from that of the tricyclic …
The methods of synthesis and the pharmacological evaluation of a new non-tricyclic antidepressant drug, N-benzo[b]furan-2-ylcarbonyl-N'-benz …
Befuraline, its safety and efficacy in depressed inpatients.
Gastpar M, Gastpar G, Gilsdorf U. Gastpar M, et al. Pharmacopsychiatry. 1985 Nov;18(6):351-5. doi: 10.1055/s-2007-1017396. Pharmacopsychiatry. 1985. PMID: 4089015
Befuraline, a new antidepressant drug, was studied in twenty-nine inpatients with unipolar endogenous depression. The evaluation of patients' condition was made on four different study periods by two assessors using the HDRS, the Beck depression inventory and von Zerssen d …
Befuraline, a new antidepressant drug, was studied in twenty-nine inpatients with unipolar endogenous depression. The evaluation of p …
[Open study of befuraline (DIV 154) in 64 depressive patients (author's transl)].
Clemens R, Clemens U. Clemens R, et al. Arzneimittelforschung. 1977;27(12):2416-21. Arzneimittelforschung. 1977. PMID: 341906 Clinical Trial. German.
Improvement was found in 33 cases (= 52%) under a daily dose of 150 mg befuraline; 31 of these patients improved within the first 8 days of treatment. Patients with endogenous depression responded favourably to the befuraline therapy, 23 (= 70%) of these (33) patien …
Improvement was found in 33 cases (= 52%) under a daily dose of 150 mg befuraline; 31 of these patients improved within the first 8 d …
Behavioural and neurochemical studies of the action of atypical antidepressants.
Valdman AV, Avdulov NA, Rozganets VV, Rusacov DY. Valdman AV, et al. Acta Physiol Pharmacol Bulg. 1983;9(3):3-10. Acta Physiol Pharmacol Bulg. 1983. PMID: 6142583
Unlike the tricyclic antidepressants which inhibit the NA, DA and 5-HT uptake, the atypical antidepressants studied (azaphen, befuraline, pirlindol, inkazan) were less active and inhibited the uptake of only one or two monoamines. ...
Unlike the tricyclic antidepressants which inhibit the NA, DA and 5-HT uptake, the atypical antidepressants studied (azaphen, befuraline …
[Synthesis and antidepressive activity study of aryl and heteroaryl carboxamides of benzylpiperazine].
Younes-El-Hage S, Labssita Y, Baziard-Mouysset G, Payard M, Caignard DH, Rubat C. Younes-El-Hage S, et al. Ann Pharm Fr. 2000 Jul;58(4):254-9. Ann Pharm Fr. 2000. PMID: 10915973 French.
The synthesis of 44 original amide derivatives of benzylpiperazine and some analogues of befuraline and piberaline is reported. All compounds have been tested as antidepressive agents. ...
The synthesis of 44 original amide derivatives of benzylpiperazine and some analogues of befuraline and piberaline is reported. All c …
11 results