Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1989 2
1990 2
1991 6
1992 2
1993 1
1994 1
1995 1
1997 1
2024 0

Text availability

Article attribute

Article type

Publication date

Search Results

16 results

Results by year

Filters applied: . Clear all
Page 1
Platelet-activating factor antagonists.
Negro Alvarez JM, Miralles López JC, Ortiz Martínez JL, Abellán Alemán A, Rubio del Barrio R. Negro Alvarez JM, et al. Allergol Immunopathol (Madr). 1997 Sep-Oct;25(5):249-58. Allergol Immunopathol (Madr). 1997. PMID: 9395010 Review.
Natural (Ginkgolides, Kadsurenone, Chantancin, Phomactin, Swietemohonin A, Prehispalone, THC-7-oic acid, Aglafoline, FR 900452, PCA 4248 and SCH 37370), and synthetic antagonists (CV-3988, CV-6209, SRI 63-072, SRI 63-441, UR-10324, UR-11353, E-5880, CL 184005, 6-Mono and Bis-aryl …
Natural (Ginkgolides, Kadsurenone, Chantancin, Phomactin, Swietemohonin A, Prehispalone, THC-7-oic acid, Aglafoline, FR 900452, PCA 4248 and …
Recovery of postischemic brain metabolism and function following treatment with a free radical scavenger and platelet-activating factor antagonists.
Gilboe DD, Kintner D, Fitzpatrick JH, Emoto SE, Esanu A, Braquet PG, Bazan NG. Gilboe DD, et al. J Neurochem. 1991 Jan;56(1):311-9. doi: 10.1111/j.1471-4159.1991.tb02597.x. J Neurochem. 1991. PMID: 1987322
We have studied the metabolic and functional effects of two new platelet-activating factor (PAF) antagonists (BN 50726 and BN 50739) and their diluent (dimethyl sulfoxide; DMSO) during reoxygenation of the 14-min ischemic isolated brain. ...PCr and CMRO2 values were …
We have studied the metabolic and functional effects of two new platelet-activating factor (PAF) antagonists (BN 50726 and BN …
Pharmacologic profile of BN 50739, a new PAF antagonist in vitro and in vivo.
Yue TL, Rabinovici R, Farhat M, Feuerstein G. Yue TL, et al. Prostaglandins. 1990 May;39(5):469-80. doi: 10.1016/0090-6980(90)90031-p. Prostaglandins. 1990. PMID: 2353116
The IC50 of BN 50739 for PAF (10 nM) induced [3H]-serotonin release was 3.67 nM. Under the same experimental condition, the IC50s of BN 50726, BN 50730, BN 50741, WEB 2086, SRI 63-441 and BN 52021 were 5.40, 4.61, 6.88, 5.98, 40.90 nM and 14.90 microM, respectively. …
The IC50 of BN 50739 for PAF (10 nM) induced [3H]-serotonin release was 3.67 nM. Under the same experimental condition, the IC50s of BN …
Inhibitory effect of new PAF antagonists on PAF-induced rabbit platelet aggregation in vitro and ex vivo.
Yue TL, Rabinovici R, Farhat M, Feuerstein G. Yue TL, et al. J Lipid Mediat. 1991 Jan-Feb;3(1):13-26. J Lipid Mediat. 1991. PMID: 1768837
The IC50 of BN 50739 for 2.5 nM PAF-induced platelet aggregation was 13.8 nM. Under the same condition, the IC50s of BN 50741, BN 50730, BN 50726, SRI 63-441 and BN 52021 were 18.3, 33.1, 63.4, 712 and 24,600 nM, respectively. ...
The IC50 of BN 50739 for 2.5 nM PAF-induced platelet aggregation was 13.8 nM. Under the same condition, the IC50s of BN 50741, BN 50730, …
Mechanisms of the platelet aggregation induced by activated neutrophils and inhibitory effect of specific PAF receptor antagonists.
Nguyên P, Petitfrère E, Potron G. Nguyên P, et al. Thromb Res. 1995 Apr 1;78(1):33-42. doi: 10.1016/0049-3848(95)00032-1. Thromb Res. 1995. PMID: 7778064
This activation involves the phosphoinositide metabolism. Specific PAF receptor antagonists gingkolides (BN 50726, BN 52021, BN 54068, BN 54062, BN 50730, BN 50749, BN 50744) and benzodiazepine Web2086 antagonize this neutrophil-induced platelet aggregation. ...
This activation involves the phosphoinositide metabolism. Specific PAF receptor antagonists gingkolides (BN 50726, BN 52021, B …
Prolonged effect of a new platelet-activating factor antagonist on ocular vascular permeability in an endotoxin model of uveitis.
Lin N, Bazan HE, Braquet P, Bazan NG. Lin N, et al. Curr Eye Res. 1991 Jan;10(1):19-24. doi: 10.3109/02713689109007607. Curr Eye Res. 1991. PMID: 1709399
Severe keratitis and anterior uveitis were induced in 3-4 days. BN 50726 was applied once subconjunctivally and then topically four times daily for 5 days in a blind-designed experiment. Vascular permeability was measured each day with an automated fluorophotometer …
Severe keratitis and anterior uveitis were induced in 3-4 days. BN 50726 was applied once subconjunctivally and then topically …
Platelet-activating factor (PAF) accumulation correlates with injury in the cornea.
Bazan HE, Reddy ST, Lin N. Bazan HE, et al. Exp Eye Res. 1991 Apr;52(4):481-91. doi: 10.1016/0014-4835(91)90046-h. Exp Eye Res. 1991. PMID: 2037028
The specificity of the aggregating bioactivity was ascertained from inhibition of platelet aggregation by selective PAF antagonists. BN 50726, a new synthetic PAF antagonist, applied in vivo topically or subconjunctivally, was effective in inhibiting PAF formation. …
The specificity of the aggregating bioactivity was ascertained from inhibition of platelet aggregation by selective PAF antagonists. BN …
The platelet-stimulating effect of adrenaline through alpha 2-adrenergic receptors requires simultaneous activation by a true stimulatory platelet agonist. Evidence that adrenaline per se does not induce human platelet activation in vitro.
Steen VM, Holmsen H, Aarbakke G. Steen VM, et al. Thromb Haemost. 1993 Sep 1;70(3):506-13. Thromb Haemost. 1993. PMID: 8259557
All experiments were performed with human gel-filtered platelets pretreated with acetylsalicylic acid to prevent endogenous stimulation by the arachidonate pathway. (1) Preliminary experiments demonstrated the presence of trace amounts of extracellular ADP (0.05-0.58 microM) in n …
All experiments were performed with human gel-filtered platelets pretreated with acetylsalicylic acid to prevent endogenous stimulation by t …
16 results