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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1972 1
1974 21
1975 70
1976 76
1977 60
1978 81
1979 71
1980 108
1981 56
1982 54
1983 56
1984 39
1985 44
1986 16
1987 25
1988 22
1989 24
1990 15
1991 14
1992 20
1993 17
1994 10
1995 23
1996 28
1997 13
1998 24
1999 17
2000 11
2001 8
2002 12
2003 13
2004 8
2005 7
2006 5
2007 6
2008 10
2009 18
2010 8
2011 16
2012 29
2013 36
2014 36
2015 35
2016 34
2017 53
2018 63
2019 48
2020 56
2021 43
2022 48
2023 37
2024 20

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1,570 results

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Page 1
Comparison of subcutaneous sedation with alfaxalone or alfaxalone-midazolam in pet guinea pigs (Cavia porcellus) of three different age groups.
Álvarez ER, Solé LV, de Carellán Mateo AG. Álvarez ER, et al. J Am Vet Med Assoc. 2022 Mar 24;260(9):1024-1030. doi: 10.2460/javma.21.02.0104. J Am Vet Med Assoc. 2022. PMID: 35333744 Free article.
PROCEDURES: The study design was a randomized, crossover, blinded, clinical trial with a washout period of at least 7 days between protocols. Guinea pigs were sedated SC with alfaxalone (5 mg/kg; group A) or alfaxalone (5 mg/kg) and midazolam (0.5 mg/kg; group A + M …
PROCEDURES: The study design was a randomized, crossover, blinded, clinical trial with a washout period of at least 7 days between protocols …
Intramuscular alfaxalone with or without buprenorphine or hydromorphone provides sedation with minimal adverse effects in healthy rabbits (Oryctolagus cuniculus) in a randomized blinded controlled trial.
Costa RS, Ciotti-McClallen M, Tilley R, Perry S, Maki L, Starks D, Stein AB. Costa RS, et al. J Am Vet Med Assoc. 2022 Dec 15;261(2):223-228. doi: 10.2460/javma.22.10.0463. J Am Vet Med Assoc. 2022. PMID: 36520651
OBJECTIVE: To evaluate the effects of alfaxalone administered IM with or without buprenorphine or hydromorphone in healthy rabbits (Oryctolagus cuniculus). ...CLINICAL RELEVANCE: All 3 treatments provided reliable sedation; however, alfaxalone (4 mg/kg, IM) combined …
OBJECTIVE: To evaluate the effects of alfaxalone administered IM with or without buprenorphine or hydromorphone in healthy rabbits (O …
Effects of midazolam before or after alfaxalone for co-induction of anaesthesia in healthy dogs.
Zapata A, Laredo FG, Escobar M, Agut A, Soler M, Belda E. Zapata A, et al. Vet Anaesth Analg. 2018 Sep;45(5):609-617. doi: 10.1016/j.vaa.2018.04.002. Epub 2018 Jun 19. Vet Anaesth Analg. 2018. PMID: 30077556 Clinical Trial.
OBJECTIVE: To study the effect of alternating the order of midazolam and alfaxalone administration on the incidence of behavioural changes, alfaxalone induction dose and some cardiorespiratory variables in healthy dogs. ...The control group (CA) was administered nor …
OBJECTIVE: To study the effect of alternating the order of midazolam and alfaxalone administration on the incidence of behavioural ch …
Alfaxalone alone or combined with midazolam or ketamine in dogs: intubation dose and select physiologic effects.
Muñoz KA, Robertson SA, Wilson DV. Muñoz KA, et al. Vet Anaesth Analg. 2017 Jul;44(4):766-774. doi: 10.1016/j.vaa.2017.01.004. Epub 2017 Mar 6. Vet Anaesth Analg. 2017. PMID: 28756063 Clinical Trial.
Additional alfaxalone (0.25 mg kg(-1) increments) was administered as required to permit endotracheal intubation. ...CONCLUSIONS AND CLINICAL RELEVANCE: Midazolam and ketamine reduced the alfaxalone dose required for endotracheal intubation. Serum glucose and insuli …
Additional alfaxalone (0.25 mg kg(-1) increments) was administered as required to permit endotracheal intubation. ...CONCLUSIONS AND …
A review of the pharmacology and clinical application of alfaxalone in cats.
Warne LN, Beths T, Whittem T, Carter JE, Bauquier SH. Warne LN, et al. Vet J. 2015 Feb;203(2):141-8. doi: 10.1016/j.tvjl.2014.12.011. Epub 2014 Dec 16. Vet J. 2015. PMID: 25582797 Free article. Review.
Alfaxalone-2-hydroxpropyl-beta-cyclodextrin (alfaxalone-HPCD) was first marketed for veterinary use in Australia in 2001 and has since progressively became available throughout the world, including the USA, where in 2012 Food and Drug Administration (FDA) registrati …
Alfaxalone-2-hydroxpropyl-beta-cyclodextrin (alfaxalone-HPCD) was first marketed for veterinary use in Australia in 2001 and h …
Pharmacokinetics and sedative effects of alfaxalone with or without dexmedetomidine in rabbits.
Marín P, Belda E, Laredo FG, Torres CA, Hernandis V, Escudero E. Marín P, et al. Res Vet Sci. 2020 Apr;129:6-12. doi: 10.1016/j.rvsc.2019.12.015. Epub 2019 Dec 19. Res Vet Sci. 2020. PMID: 31901533
Dexmedetomidine enhanced and increase the duration of the sedative effects of alfaxalone. In conclusion, alfaxalone administered in rabbits provides rapid and smooth onset of sedation. After IV and IM injections of alfaxalone combined with dexmedetomidine, a …
Dexmedetomidine enhanced and increase the duration of the sedative effects of alfaxalone. In conclusion, alfaxalone administer …
Alfaxalone anaesthesia in Lemur catta following dexmedetomidine-butorphanol-midazolam sedation.
Gaudio E, Voltan L, De Benedictis GM. Gaudio E, et al. Vet Anaesth Analg. 2018 May;45(3):351-356. doi: 10.1016/j.vaa.2018.01.004. Epub 2018 Feb 3. Vet Anaesth Analg. 2018. PMID: 29625917
OBJECTIVE: To evaluate the clinical effects and quality of sedation, induction, maintenance and recovery in Lemur catta after dexmedetomidine-butorphanol-midazolam sedation and alfaxalone anaesthesia. STUDY DESIGN: Prospective, observational study. ...Alfaxalone con …
OBJECTIVE: To evaluate the clinical effects and quality of sedation, induction, maintenance and recovery in Lemur catta after dexmedetomidin …
Comparison of Sedative Effects of Alfaxalone-Ketamine and Alfaxalone-Midazolam Administered Intramuscularly in Chickens.
Chang S, Legg-St Pierre CB, Ambros B. Chang S, et al. J Avian Med Surg. 2022 May;36(1):21-27. doi: 10.1647/20-00111. J Avian Med Surg. 2022. PMID: 35526161
A prospective, randomized blinded crossover study design with a 7-day washout period was used. Nine adult layer hens received alfaxalone 15 mg/kg with ketamine 5 mg/kg IM (treatment AK) or alfaxalone 15 mg/kg with midazolam 1 mg/kg IM (treatment AM). ...Further inve …
A prospective, randomized blinded crossover study design with a 7-day washout period was used. Nine adult layer hens received alfaxalone …
Clinical review of the pharmacological and anaesthetic effects of alfaxalone in dogs.
Martín Bellido V, Vettorato E. Martín Bellido V, et al. J Small Anim Pract. 2022 May;63(5):341-361. doi: 10.1111/jsap.13454. Epub 2021 Dec 10. J Small Anim Pract. 2022. PMID: 34893985 Review.
Furthermore, quality of induction and recovery after alfaxalone administration, the use of alfaxalone for total intravenous anaesthesia, and its effects on the cardio-respiratory system, on laryngeal motion, on intraocular pressure and tear production have been eval …
Furthermore, quality of induction and recovery after alfaxalone administration, the use of alfaxalone for total intravenous an …
A randomized clinical trial on effects of alfaxalone combined with medetomidine and midazolam in preventing stress-related neurohormonal and metabolic responses of isoflurane-anesthetized cats undergoing surgery.
Kamohara H, Kamohara T, Hikasa Y. Kamohara H, et al. Am J Vet Res. 2022 Sep 19;83(11):1-10. doi: 10.2460/ajvr.22.03.0041. Am J Vet Res. 2022. PMID: 36103386 Free article.
PROCEDURES: For each type of surgery, cats were assigned to 1 of 6 premedication protocols groups, with 6 cats/group: physiologic saline (0.9% NaCl) solution (0.5 mL, IM) and alfaxalone (5 mg/kg, IV); physiologic saline solution (0.5 mL, IM) and alfaxalone (5 mg/kg, …
PROCEDURES: For each type of surgery, cats were assigned to 1 of 6 premedication protocols groups, with 6 cats/group: physiologic saline (0. …
1,570 results