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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1946 12
1947 5
1948 3
1949 5
1950 1
1951 2
1952 1
1954 1
1960 3
1961 2
1962 3
1963 1
1969 2
1971 1
1972 1
1976 4
1977 3
1978 3
1979 1
1980 2
1981 6
1983 2
1984 12
1985 6
1986 3
1987 2
1988 4
1989 4
1990 6
1991 7
1992 6
1993 5
1994 4
1995 7
1996 2
1997 4
1998 8
1999 7
2000 3
2001 12
2002 7
2003 8
2004 9
2005 10
2006 14
2007 7
2008 13
2009 8
2010 17
2011 29
2012 24
2013 29
2014 40
2015 37
2016 42
2017 34
2018 37
2019 47
2020 36
2021 52
2022 41
2023 36
2024 13

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711 results

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Page 1
8-Aminoquinoline Therapy for Latent Malaria.
Baird JK. Baird JK. Clin Microbiol Rev. 2019 Jul 31;32(4):e00011-19. doi: 10.1128/CMR.00011-19. Print 2019 Sep 18. Clin Microbiol Rev. 2019. PMID: 31366609 Free PMC article. Review.
The technical genesis and practice of 8-aminoquinoline therapy of latent malaria offer singular scientific, clinical, and public health insights. ...After 40 years of fitful development, in 2018 the U.S. Food and Drug Administration registered the 8-aminoq …
The technical genesis and practice of 8-aminoquinoline therapy of latent malaria offer singular scientific, clinical, and publ …
Remote C-H Functionalization of 8-Aminoquinoline Ring.
Xu Z, Yang X, Yin SF, Qiu R. Xu Z, et al. Top Curr Chem (Cham). 2020 Jun 10;378(4):42. doi: 10.1007/s41061-020-00303-9. Top Curr Chem (Cham). 2020. PMID: 32524210 Review.
8-Aminoquinoline is a common nitrogen-containing heterocyclic framework in many natural products, functional materials and useful drugs. It has been developed as a powerful bidentate directing group or ligand auxiliary in the field of C-H bond activation/functionali …
8-Aminoquinoline is a common nitrogen-containing heterocyclic framework in many natural products, functional materials and use …
Tafenoquine: a toxicity overview.
Chu CS, Hwang J. Chu CS, et al. Expert Opin Drug Saf. 2021 Mar;20(3):349-362. doi: 10.1080/14740338.2021.1859476. Epub 2021 Jan 4. Expert Opin Drug Saf. 2021. PMID: 33306921 Free PMC article.
Tafenoquine for the treatment of Plasmodium vivax malaria.
Llanos-Cuentas A, Manrrique P, Rosas-Aguirre A, Herrera S, Hsiang MS. Llanos-Cuentas A, et al. Expert Opin Pharmacother. 2022 May;23(7):759-768. doi: 10.1080/14656566.2022.2058394. Epub 2022 Apr 13. Expert Opin Pharmacother. 2022. PMID: 35379070 Review.
P. vivax is characterized by the production of liver hypnozoites that cause clinical relapses upon periodic activation. Primaquine, an 8-aminoquinoline drug, has been the standard of care for decades to treat liver-stage P. vivax malaria; however, it requires long t …
P. vivax is characterized by the production of liver hypnozoites that cause clinical relapses upon periodic activation. Primaquine, an 8 …
Metal-Free C-5 Hydroxylation of 8-Aminoquinoline Amide.
Mondal S, Hajra A. Mondal S, et al. J Org Chem. 2018 Sep 21;83(18):11392-11398. doi: 10.1021/acs.joc.8b01635. Epub 2018 Aug 23. J Org Chem. 2018. PMID: 30095252
Diacetoxyiodobenzene-mediated remote hydroxylation of 8-aminoquinoline amide at the C-5 position has been developed. ...
Diacetoxyiodobenzene-mediated remote hydroxylation of 8-aminoquinoline amide at the C-5 position has been developed. ...
Methaemoglobinaemia and the radical curative efficacy of 8-aminoquinoline antimalarials.
White NJ, Watson JA, Baird JK. White NJ, et al. Br J Clin Pharmacol. 2022 Jun;88(6):2657-2664. doi: 10.1111/bcp.15219. Epub 2022 Jan 27. Br J Clin Pharmacol. 2022. PMID: 34997616 Free PMC article. Review.
Methaemoglobin results from the oxidation of ferrous to ferric iron in the centre of the haem moiety of haemoglobin. The production of dose-dependent methaemoglobinaemia by 8-aminoquinoline antimalarial drugs appears to be associated with, but is not directly linked …
Methaemoglobin results from the oxidation of ferrous to ferric iron in the centre of the haem moiety of haemoglobin. The production of dose- …
Iron-Catalyzed C-H Functionalizations under Triazole-Assistance.
Lanzi M, Cera G. Lanzi M, et al. Molecules. 2020 Apr 15;25(8):1806. doi: 10.3390/molecules25081806. Molecules. 2020. PMID: 32326406 Free PMC article. Review.
Very recently, triazoles DGs were demonstrated to be more than an excellent alternative to the commonly employed 8-aminoquinoline (AQ) DG, as a result of their modular synthesis as well as the mild reaction conditions applied for their removal. ...
Very recently, triazoles DGs were demonstrated to be more than an excellent alternative to the commonly employed 8-aminoquinoline …
The Role of 8-Amidoquinoline Derivatives as Fluorescent Probes for Zinc Ion Determination.
Mohamad NS, Zakaria NH, Daud N, Tan LL, Ta GC, Heng LY, Hassan NI. Mohamad NS, et al. Sensors (Basel). 2021 Jan 5;21(1):311. doi: 10.3390/s21010311. Sensors (Basel). 2021. PMID: 33466407 Free PMC article. Review.
Introducing various carboxamide groups into an 8-aminoquinoline molecule to create 8-amidoquinoline derivatives to improve water solubility and cell membrane permeability is also a recent trend. This review aims to present a general overview of the fluorophore 8 …
Introducing various carboxamide groups into an 8-aminoquinoline molecule to create 8-amidoquinoline derivatives to improve wat …
Primaquine-induced haemolysis in females heterozygous for G6PD deficiency.
Chu CS, Bancone G, Nosten F, White NJ, Luzzatto L. Chu CS, et al. Malar J. 2018 Mar 2;17(1):101. doi: 10.1186/s12936-018-2248-y. Malar J. 2018. PMID: 29499733 Free PMC article. Review.
Two recent studies (in 2017) have provided precisely such data; and the need has emerged for the development of point of care quantitative testing of G6PD activity. Another priority is exploring alternative 8-aminoquinoline dosing regimens that are practical and imp …
Two recent studies (in 2017) have provided precisely such data; and the need has emerged for the development of point of care quantitative t …
711 results