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3'-Deoxy-3'-fluoroinosine as a potent antileishmanial agent. The metabolism and selective cytotoxic effect of 3'-deoxy-3'-fluoroinosine against Leishmania tropica and L. donovani in vitro and in vivo.
Shin IS, Tanifuji H, Arata Y, Morizawa Y, Nakayama T, Wataya Y. Shin IS, et al. Parasitol Res. 1995;81(7):622-6. doi: 10.1007/BF00932030. Parasitol Res. 1995. PMID: 7479655
We studied the antileishmanial activity of 3'-deoxy-3'-fluoroinosine (3'-FI) against Leishmania tropica and L. donovani. ...
We studied the antileishmanial activity of 3'-deoxy-3'-fluoroinosine (3'-FI) against Leishmania tropica and L. d …
Invention of anti-Leishmania drugs on the basis of the nucleoside structures.
Wataya Y, Tanifuji H, Kubochi F, Yoshioka-Hiramoto A, Morishige K, Ishii A, Morizawa Y, Nakayama T, Yasuda A, Matsuda A, et al. Wataya Y, et al. Nucleic Acids Symp Ser. 1990;(22):23-4. Nucleic Acids Symp Ser. 1990. PMID: 2101903
3'-Deoxy-3'-fluoroinosine is a potent inhibitor for the growth of the promastigote form of Leishmania tropica and Leishmania donovani. ...This metabolic conversion provides a mechanism for the parasite-selective toxicity of 3'-deoxy-3
3'-Deoxy-3'-fluoroinosine is a potent inhibitor for the growth of the promastigote form of Leishmania tropica an