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Page 1
A new parasiticidal compound in T. solium cysticercosis.
Hernández-Bello R, Escobedo G, Carrero JC, Cervantes-Rebolledo C, Dowding C, Frincke J, Reading C, Morales-Montor J. Hernández-Bello R, et al. Biomed Res Int. 2013;2013:505240. doi: 10.1155/2013/505240. Epub 2012 Dec 20. Biomed Res Int. 2013. PMID: 23509732 Free PMC article.
16-bromoepiandrosterone, an activator of the mammalian immune system, inhibits glucose 6-phosphate dehydrogenase from Trypanosoma cruzi and is toxic to these parasites grown in culture.
Cordeiro AT, Thiemann OH. Cordeiro AT, et al. Bioorg Med Chem. 2010 Jul 1;18(13):4762-8. doi: 10.1016/j.bmc.2010.05.008. Epub 2010 May 7. Bioorg Med Chem. 2010. PMID: 20570159 Free article.
In the present work, we investigated the in vitro effect of DHEA derivatives on the proliferation of T. cruzi epimastigotes and their inhibitory effect on a recombinant form of the parasite's G6PDH (TcG6PDH). Our results show that DHEA and its derivative epiandrosterone (E …
In the present work, we investigated the in vitro effect of DHEA derivatives on the proliferation of T. cruzi epimastigotes and their inhibi …
Dehydroepiandrosterone and 16 alpha-bromo-epiandrosterone: inhibitors of Epstein-Barr virus-induced transformation of human lymphocytes.
Henderson E, Schwartz A, Pashko L, Abou-Gharbia M, Swern D. Henderson E, et al. Carcinogenesis. 1981;2(7):683-6. doi: 10.1093/carcin/2.7.683. Carcinogenesis. 1981. PMID: 6268330
DHEA is now shown to inhibit Epstein-Barr virus (EBV)-induced morphologic transformation and stimulation of DNA synthesis in human lymphocytes. 16 alpha-Br-epiandrosterone, a DHEA analog that is about 60 times as potent as DHEA as an inhibitor of G6PDH, is much more effect …
DHEA is now shown to inhibit Epstein-Barr virus (EBV)-induced morphologic transformation and stimulation of DNA synthesis in human lymphocyt …
13 results