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Counteractive effect of Paeonia lactiflora root constituent mudanpioside E against suppressive effect of Shoseiryuto-extract on passive cutaneous anaphylaxis reaction in mice.
Tsukamoto K, Yamamoto K, Makino T. Tsukamoto K, et al. J Ethnopharmacol. 2014 May 14;153(3):884-9. doi: 10.1016/j.jep.2014.03.053. Epub 2014 Apr 1. J Ethnopharmacol. 2014. PMID: 24704488
Among the eight crude drugs comprising SST, Asiasarum root, Pinellia tuber, and Glycyrrhiza contributed positively, and Peony root contributed negatively to the anti-allergic effects of SST. We isolated mudanpioside E from the extract of Peony root as the counteract …
Among the eight crude drugs comprising SST, Asiasarum root, Pinellia tuber, and Glycyrrhiza contributed positively, and Peony root contribut …
Revealing metabolomic variations in Cortex Moutan from different root parts using HPLC-MS method.
Xiao C, Wu M, Chen Y, Zhang Y, Zhao X, Zheng X. Xiao C, et al. Phytochem Anal. 2015 Jan-Feb;26(1):86-93. doi: 10.1002/pca.2539. Epub 2014 Sep 17. Phytochem Anal. 2015. PMID: 25230378
Higher levels of malic acid, gallic acid and mudanoside-B were mainly observed in the second lateral roots, whereas dihydroxyacetophenone, benzoyloxypaeoniflorin, suffruticoside-A, kaempferol dihexoside, mudanpioside E and mudanpioside J accumulated in the first lat …
Higher levels of malic acid, gallic acid and mudanoside-B were mainly observed in the second lateral roots, whereas dihydroxyacetophenone, b …
Chemical constituents with anti-allergic activity from the root of Edulis Superba, a horticultural cultivar of Paeonia lactiflora.
Shi YH, Zhu S, Tamura T, Kadowaki M, Wang Z, Yoshimatsu K, Komatsu K. Shi YH, et al. J Nat Med. 2016 Apr;70(2):234-40. doi: 10.1007/s11418-016-0966-4. Epub 2016 Jan 30. J Nat Med. 2016. PMID: 26833191
The chemical structure of the new compound was elucidated on the basis of spectroscopic and chemical evidences. Among the isolated compounds, mudanpioside E (5) with paeoniflorin-type skeleton and quercetin (16) showed potent inhibitory activity against a degranulat …
The chemical structure of the new compound was elucidated on the basis of spectroscopic and chemical evidences. Among the isolated compounds …
Suffruyabiosides A and B, two new monoterpene diglycosides from moutan cortex.
Furuya R, Hu H, Zhang Z, Shigemori H. Furuya R, et al. Molecules. 2012 Apr 30;17(5):4915-23. doi: 10.3390/molecules17054915. Molecules. 2012. PMID: 22547314 Free PMC article.
An increase in the number of phenolic hydroxyl groups produced a more effective radical scavenging effect [8 > mudanpioside E (6) > oxypaeoniflorin (5)]. Comparison of the effects of 4 and 5 showed that o-substitution with a phenolic hydroxyl group was more ef …
An increase in the number of phenolic hydroxyl groups produced a more effective radical scavenging effect [8 > mudanpioside E