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1978 | 2 |
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Quoted phrase not found in phrase index: "methyl bicyclophosphate"
Page 1
Distribution and metabolic fate in mammals of the potent convulsant and GABA antagonist t-butyl-bicyclophosphate and its methyl analog.
Toxicol Appl Pharmacol. 1978 Nov;46(2):411-20. doi: 10.1016/0041-008x(78)90086-8.
Toxicol Appl Pharmacol. 1978.
PMID: 734670
No abstract available.
Isoguvacine, isonipecotic acid, muscimol and N-methyl isoguvacine on the GABA receptor in rat sympathetic ganglia.
Bowery NG, Collins JF, Hudson AL, Neal MJ.
Bowery NG, et al.
Experientia. 1978 Sep 15;34(9):1193-5. doi: 10.1007/BF01922953.
Experientia. 1978.
PMID: 214333
The GABA-mimetic activities of 4 analogues muscimol, isonipecotic acid, isoguvacine and N-methyl isoguvacine have been examined at the GABA receptor in the rat isolated superior cervical ganglion. ...The potency of isoguvacine was 0.23 +/- 0.026 and isonipecotic acid 0.011 …
The GABA-mimetic activities of 4 analogues muscimol, isonipecotic acid, isoguvacine and N-methyl isoguvacine have been examined at th …
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gamma-Aminobutyric acid- and benzodiazepine-induced modulation of [35S]-t-butylbicyclophosphorothionate binding to cerebellar granule cells.
Gallo V, Wise BC, Vaccarino F, Guidotti A.
Gallo V, et al.
J Neurosci. 1985 Sep;5(9):2432-8. doi: 10.1523/JNEUROSCI.05-09-02432.1985.
J Neurosci. 1985.
PMID: 4032005
Free PMC article.
t-Butylbicyclophosphorothionate (TBPS) is a bicyclophosphate derivative with potent picrotoxin-like convulsant activity that binds with high affinity and specificity to a Cl- channel-modulatory site of the gamma-aminobutyric acid (GABA)/benzodiazepine receptor complex. ...
t-Butylbicyclophosphorothionate (TBPS) is a bicyclophosphate derivative with potent picrotoxin-like convulsant activity that binds wi …
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Studies on the post-ictal rise in seizure threshold.
Nutt DJ, Cowen PJ, Green AR.
Nutt DJ, et al.
Eur J Pharmacol. 1981 May 8;71(2-3):287-95. doi: 10.1016/0014-2999(81)90031-5.
Eur J Pharmacol. 1981.
PMID: 6113969
Following an electroconvulsive shock (ECS) rats exhibited a raised seizure threshold to infusion of the GABA antagonist drugs, pentylenetetrazol, bicuculline and isopropyl-bicyclophosphate, but not to the glycine antagonist strychnine or the 5-HT agonist, quipazine. ...The …
Following an electroconvulsive shock (ECS) rats exhibited a raised seizure threshold to infusion of the GABA antagonist drugs, pentylenetetr …
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