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Quoted phrase not found in phrase index: "Phospho Lean"
Page 1
Adipocyte-derived extracellular vesicles increase insulin secretion through transport of insulinotropic protein cargo.
Kulaj K, Harger A, Bauer M, Caliskan ÖS, Gupta TK, Chiang DM, Milbank E, Reber J, Karlas A, Kotzbeck P, Sailer DN, Volta F, Lutter D, Prakash S, Merl-Pham J, Ntziachristos V, Hauner H, Pfaffl MW, Tschöp MH, Müller TD, Hauck SM, Engel BD, Gerdes JM, Pfluger PT, Krahmer N, Stemmer K. Kulaj K, et al. Nat Commun. 2023 Feb 9;14(1):709. doi: 10.1038/s41467-023-36148-1. Nat Commun. 2023. PMID: 36759608 Free PMC article.
Notably, insulinotropic effects were restricted to AdEVs isolated from obese and insulin resistant, but not lean mice, which was consistent with differential protein loads and AdEV luminal morphologies. Likewise, in vivo pre-treatment with AdEVs from obese but not lean …
Notably, insulinotropic effects were restricted to AdEVs isolated from obese and insulin resistant, but not lean mice, which was cons …
Targeting Neutrophil α9 Improves Functional Outcomes After Stroke in Mice With Obesity-Induced Hyperglycemia.
Patel RB, Dhanesha N, Sutariya B, Ghatge M, Doddapattar P, Barbhuyan T, Kumskova M, Leira EC, Chauhan AK. Patel RB, et al. Stroke. 2023 Sep;54(9):2409-2419. doi: 10.1161/STROKEAHA.123.042714. Epub 2023 Jul 14. Stroke. 2023. PMID: 37449422 Free article.
Infarct volume (magnetic resonance imaging) and postreperfusion thrombo-inflammation (thrombi, fibrin, neutrophil, phospho-nuclear factor kappa B [p-NFkappaB], TNF [tumor necrosis factor]-alpha, and IL [interleukin]-1beta levels, markers of neutrophil extracellular traps) …
Infarct volume (magnetic resonance imaging) and postreperfusion thrombo-inflammation (thrombi, fibrin, neutrophil, phospho-nuclear fa …
Adipocyte coculture induces a pro-inflammatory, fibrotic, angiogenic, and proliferative microenvironment in uterine leiomyoma cells.
Afrin S, El Sabah M, Manzoor A, Miyashita-Ishiwata M, Reschke L, Borahay MA. Afrin S, et al. Biochim Biophys Acta Mol Basis Dis. 2023 Jan 1;1869(1):166564. doi: 10.1016/j.bbadis.2022.166564. Epub 2022 Sep 29. Biochim Biophys Acta Mol Basis Dis. 2023. PMID: 36181981 Free PMC article.
Other protein abundances were determined using western blots. The expression levels of TNF-alpha, MCP-1, phospho-NF-kappaB, TGFbeta3 and VEGF-A in lean and obese in different leiomyoma patients were determined by immunofluorescence staining. ...Obese leiomyoma patie …
Other protein abundances were determined using western blots. The expression levels of TNF-alpha, MCP-1, phospho-NF-kappaB, TGFbeta3 …
Disruption of STIM1-mediated Ca(2+) sensing and energy metabolism in adult skeletal muscle compromises exercise tolerance, proteostasis, and lean mass.
Wilson RJ, Lyons SP, Koves TR, Bryson VG, Zhang H, Li T, Crown SB, Ding JD, Grimsrud PA, Rosenberg PB, Muoio DM. Wilson RJ, et al. Mol Metab. 2022 Mar;57:101429. doi: 10.1016/j.molmet.2021.101429. Epub 2021 Dec 31. Mol Metab. 2022. PMID: 34979330 Free PMC article.
Inducible tissue-specific deletion of STIM1 (iSTIM1 KO) in adult muscle led to diminished lean mass, reduced exercise capacity, and perturbed fuel selection in the settings of energetic stress, without affecting whole-body glucose tolerance. Proteomics and phospho-p …
Inducible tissue-specific deletion of STIM1 (iSTIM1 KO) in adult muscle led to diminished lean mass, reduced exercise capacity, and p …
Obesity decreases B cell responses in young and elderly individuals.
Frasca D, Ferracci F, Diaz A, Romero M, Lechner S, Blomberg BB. Frasca D, et al. Obesity (Silver Spring). 2016 Mar;24(3):615-25. doi: 10.1002/oby.21383. Epub 2016 Feb 9. Obesity (Silver Spring). 2016. PMID: 26857091 Free PMC article.
Leptin increased phospho-STAT3, crucial for TNF-alpha production, and decreased phospho-AMPK, the energy sensing enzyme upstream of phospho-p38 MAPK and E47. Leptin-induced phospho-STAT3 and phospho-AMPK levels were similar to those in B cells f …
Leptin increased phospho-STAT3, crucial for TNF-alpha production, and decreased phospho-AMPK, the energy sensing enzyme upstre …
Bone health and body composition in transgender adults before gender-affirming hormonal therapy: data from the COMET study.
Ceolin C, Scala A, Dall'Agnol M, Ziliotto C, Delbarba A, Facondo P, Citron A, Vescovi B, Pasqualini S, Giannini S, Camozzi V, Cappelli C, Bertocco A, De Rui M, Coin A, Sergi G, Ferlin A, Garolla A; Gender Incongruence Interdisciplinary Group (GIIG). Ceolin C, et al. J Endocrinol Invest. 2024 Feb;47(2):401-410. doi: 10.1007/s40618-023-02156-7. Epub 2023 Jul 14. J Endocrinol Invest. 2024. PMID: 37450195 Free PMC article.

AFAB transgender people had more total fat mass, while AMAB transgender individuals had reduced total lean mass as compared to cisgender people (53.94 7.74 vs 58.38 6.91, p < 0.05). ...Fat Mass Index (FMI) was correlated with lumbar and femur BMD both in transgender ind

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AFAB transgender people had more total fat mass, while AMAB transgender individuals had reduced total lean mass as compared to cisgen …
Lipid-induced insulin resistance is prevented in lean and obese myotubes by AICAR treatment.
Bikman BT, Zheng D, Reed MA, Hickner RC, Houmard JA, Dohm GL. Bikman BT, et al. Am J Physiol Regul Integr Comp Physiol. 2010 Jun;298(6):R1692-9. doi: 10.1152/ajpregu.00190.2009. Epub 2010 Apr 14. Am J Physiol Regul Integr Comp Physiol. 2010. PMID: 20393162 Free PMC article.
To better understand the divergent response to lipid exposure between lean and obese, we incubated primary human muscle cells from lean [body mass index (BMI) <25 kg/m(2)] and morbidly obese (BMI >40 kg/m(2)) subjects with the saturated fatty acid palmitate. . …
To better understand the divergent response to lipid exposure between lean and obese, we incubated primary human muscle cells from …
Analytical and computational workflow for in-depth analysis of oxidized complex lipids in blood plasma.
Criscuolo A, Nepachalovich P, Garcia-Del Rio DF, Lange M, Ni Z, Baroni M, Cruciani G, Goracci L, Blüher M, Fedorova M. Criscuolo A, et al. Nat Commun. 2022 Nov 1;13(1):6547. doi: 10.1038/s41467-022-33225-9. Nat Commun. 2022. PMID: 36319635 Free PMC article.
The developed methodology is used to identify epilipidomics signatures of lean and obese individuals with and without type 2 diabetes. The characteristic signature of lipid modifications in lean individuals, dominated by the presence of modified octadecanoid acyl ch …
The developed methodology is used to identify epilipidomics signatures of lean and obese individuals with and without type 2 diabetes …
Cardioprotective Effect of Glycyrrhizin on Myocardial Remodeling in Diabetic Rats.
Thakur V, Alcoreza N, Delgado M, Joddar B, Chattopadhyay M. Thakur V, et al. Biomolecules. 2021 Apr 13;11(4):569. doi: 10.3390/biom11040569. Biomolecules. 2021. PMID: 33924458 Free PMC article.
Our study demonstrates that hyperglycemia can elevate cardiac atrophy in diabetic animals. Type 2 diabetic fatty and the lean control rats were evaluated for cardiac damage and inflammation at 8-12 weeks after the development of diabetes. ...We also observed an increase in …
Our study demonstrates that hyperglycemia can elevate cardiac atrophy in diabetic animals. Type 2 diabetic fatty and the lean control …
Obesity causes PGC-1α deficiency in the pancreas leading to marked IL-6 upregulation via NF-κB in acute pancreatitis.
Pérez S, Rius-Pérez S, Finamor I, Martí-Andrés P, Prieto I, García R, Monsalve M, Sastre J. Pérez S, et al. J Pathol. 2019 Jan;247(1):48-59. doi: 10.1002/path.5166. Epub 2018 Dec 11. J Pathol. 2019. PMID: 30221360 Free article.
Lean and obese Zucker rats and lean and obese C57BL6 mice were used first; subsequently, wild-type and PGC-1alpha knockout (KO) mice with cerulein-induced pancreatitis were used to assess the inflammatory response and expression of target genes. ...The lack of PGC-1 …
Lean and obese Zucker rats and lean and obese C57BL6 mice were used first; subsequently, wild-type and PGC-1alpha knockout (KO …
63 results