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Identification of ent-16 beta, 17-dihydroxykauran-19-oic acid as an anti-HIV principle and isolation of the new diterpenoids annosquamosins A and B from Annona squamosa.
J Nat Prod. 1996 Jun;59(6):635-7. doi: 10.1021/np960416j.
J Nat Prod. 1996.
PMID: 8786370
Phytochemical analysis of the fruits of Annona squamosa yielded 12 known kaurane derivatives (1-11, 13) and two new kaurane diterpenoids, which have been named annosquamosin A (16 beta-hydroxy-17-acetoxy-ent-kauran-19-al) (12) and annosquamosin B (19-nor-ent-kaurane …
Phytochemical analysis of the fruits of Annona squamosa yielded 12 known kaurane derivatives (1-11, 13) and two new kaurane diterpenoids, wh …
[Constituents from the bark of Annona squamosa and their anti-tumor activity].
Sun L, Zhu H, Gan L, Mo J, Feng F, Zhou C.
Sun L, et al.
Zhongguo Zhong Yao Za Zhi. 2012 Jul;37(14):2100-4.
Zhongguo Zhong Yao Za Zhi. 2012.
PMID: 23126192
Chinese.
The structures were determined as: annosquamosin C(1),15, 16-epoxy-17-hydroxy-ent-kau-ran-19-oic acid (2),16,17-dihydroxy-ent-kau-ran-19-oic acid(3), annosquamosin A(4), ent-kaur-16-en-19-oic acid (5), 19-nor-ent-kauran4-ol-17-oic acid (6),16-hydroxy ent-kau ran-19-oic acid (7), …
The structures were determined as: annosquamosin C(1),15, 16-epoxy-17-hydroxy-ent-kau-ran-19-oic acid (2),16,17-dihydroxy-ent-kau-ran-19-oic …
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Annosquacin B induces mitochondrial apoptosis in multidrug resistant human breast cancer cell line MCF-7/ADR through selectively modulating MAPKs pathways.
Yuan F, Bai G, Miao Y, Chen Y, Li X, Chen J.
Yuan F, et al.
Pharm Biol. 2016 Dec;54(12):3040-3045. doi: 10.1080/13880209.2016.1200634. Epub 2016 Jul 22.
Pharm Biol. 2016.
PMID: 27450387
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